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Lingua: Inglese
Editore: LAP LAMBERT Academic Publishing, 2010
ISBN 10: 3838323947 ISBN 13: 9783838323947
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. NON-PROTEIN-CODING RNAS MEDIATE FINE-TUNED GENE EXPRESSION | VOLUME ONE: REGULATORY ROLES OF NATURAL ANTISENSE TRANSCRIPTS | Mohammad Ali Faghihi | Taschenbuch | 128 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838323947 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.
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Lingua: Inglese
Editore: LAP Lambert Academic Publishing, 2009
ISBN 10: 3838323947 ISBN 13: 9783838323947
Da: Revaluation Books, Exeter, Regno Unito
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Aggiungi al carrelloPaperback. Condizione: Brand New. 128 pages. 8.66x5.91x0.28 inches. In Stock.
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Aggiungi al carrelloCondizione: Sehr gut. Zustand: Sehr gut | Seiten: 412 | Sprache: Englisch | Produktart: Bücher | The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows ¿RNA¿ Nobels for splicing and RNA catalysis, highlights just one class of recently discovered non-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life. The resulting understanding of the physical and chemical processes at the molecular level is critical to our ability to harness RNA for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.
Da: One Planet Books, Columbia, MO, U.S.A.
paperback. Condizione: Like New. Ships in a BOX from Central Missouri! Like Brand NEW. No tears, highlighting or writing because it's never been used! May have minor shelf wear. UPS shipping for most packages, (Priority Mail for AK/HI/APO/PO Boxes). Softcover reprint of hardcover 1st ed. 2009.
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paperback. Condizione: New. Ships in a BOX from Central Missouri! UPS shipping for most packages, (Priority Mail for AK/HI/APO/PO Boxes). Softcover reprint of hardcover 1st ed. 2009.
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Aggiungi al carrelloCondizione: As New. Unread book in perfect condition.
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Lingua: Inglese
Editore: Springer, Springer International Publishing, 2026
ISBN 10: 3032085292 ISBN 13: 9783032085290
Da: AHA-BUCH GmbH, Einbeck, Germania
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Aggiungi al carrelloBuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book explores the intricate world of epigenetics and its pivotal role in precision medicine and the identification of epigenetic biomarkers for patient stratification, highlighting the importance of non-coding RNAs (ncRNAs), DNA methylation and histone modifications. The book discusses various epigenetic drugs, such as HDAC inhibitors and DNA methyltransferase inhibitors, targeting specific pathways to provide new therapeutic avenues.An important part in each chapter is dedicated to in silico analysis in epigenetics, including genome-wide association studies to identify correlations between genetic variations and epigenetic changes. It also covers computational models that simulate the effects of epigenetic modifications on cellular behaviour, providing insights into clinical trials with prodrugs in various types of cancer.The book focuses on the crucial role of gut microorganisms in hormone metabolism, synthesis of bioactive compounds and maintenance of the immune response, influencing endocrine homeostasis. It explores the interplay between gut microbiota, ncRNAs and endocrine regulation, focusing on endocrine-related cancers. The impact of the gut microbiome on host health through epigenetic changes is examined in depth, with a particular focus on the role of ncRNAs in host-microbe interactions.Advances in liver cell epigenetics are discussed, showing how epigenetic changes contribute to liver disorders and the potential for epigenetic-based therapeutic approaches. The book also addresses the impact of epigenetic modifications in colorectal cancer and breast cancer highlighting their role in inflammation, vascular function and lipid metabolism.Special attention is given to the importance of epigenetics and precision medicine in the context of rare cancers, blood disorders and immune-related diseases. The book reviews current literature, clinical trials and case studies, providing an overview of therapeutic potentials and innovations. It emphasises the importance of patient-centred approaches, collaborative research networks and ethical considerations in advancing the field.This book synthesises findings on the contributions of epigenetics and precision medicine to the treatment of various diseases, advocating interdisciplinary research and continuing education to improve patient care and outcomes.
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. Non-Protein Coding RNAs | Nils Walter (u. a.) | Taschenbuch | xi | Englisch | 2010 | Springer | EAN 9783642089800 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Condizione: New. pp. xi + 398.
Lingua: Inglese
Editore: Springer Berlin Heidelberg, 2010
ISBN 10: 3642089801 ISBN 13: 9783642089800
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows 'RNA' Nobels for splicing and RNA catalysis, highlights just one class of recently discovered non-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life. The resulting understanding of the physical and chemical processes at the molecular level is critical to our ability to harness RNA for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.
Lingua: Inglese
Editore: Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2008
ISBN 10: 3540708332 ISBN 13: 9783540708339
Da: AHA-BUCH GmbH, Einbeck, Germania
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Aggiungi al carrelloBuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The 2006 Nobel Prize in Physiology or Medicine was awarded to the discoverers of RNA interference, Andrew Fire and Craig Mello. This prize, which follows 'RNA' Nobels for splicing and RNA catalysis, highlights just one class of recently discovered non-protein coding RNAs. Remarkably, non-coding RNAs are thought to outnumber protein coding genes in mammals by perhaps as much as four-fold. In fact, it appears that the complexity of an organism correlates with the fraction of its genome devoted to non-protein coding RNAs. Essential biological processes as diverse as cell differentiation, suppression of infecting viruses and parasitic tra- posons, higher-level organization of eukaryotic chromosomes, and gene expression are found to be largely directed by non-protein coding RNAs. Currently, bioinformatic, high-throughput sequencing, and biochemical approaches are identifying an increasing number of these RNAs. Unfortunately, our ability to characterize the molecular details of these RNAs is significantly lacking. The biophysical study of these RNAs is an emergent field that is unraveling the molecular underpinnings of how RNA fulfills its multitude of roles in sustaining cellular life. The resulting understanding of the physical and chemical processes at the molecular level is critical to our ability to harness RNA for use in biotechnology and human therapy, a prospect that has recently spawned a multi-billion dollar industry.
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Aggiungi al carrelloHardcover. Condizione: Brand New. 250 pages. 9.25x6.10x9.49 inches. In Stock.
Lingua: Inglese
Editore: Springer Berlin Heidelberg, 2010
ISBN 10: 3642089801 ISBN 13: 9783642089800
Da: Revaluation Books, Exeter, Regno Unito
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Aggiungi al carrelloPaperback. Condizione: Brand New. 409 pages. 9.00x6.00x0.97 inches. In Stock.
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Aggiungi al carrelloHardcover. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
Lingua: Inglese
Editore: LAP LAMBERT Academic Publishing Sep 2010, 2010
ISBN 10: 3838323947 ISBN 13: 9783838323947
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Natural antisense transcripts: The human genome sequencing projects revealed that the human genome consist of over 3 billion DNA base pairs, but only contain 20,000 25,000 genes that are encoding proteins. Recent studies have revealed that eukaryotic genomes are almost entirely transcribed, generating an enormous number of non-protein-coding RNAs. Several classes of functional non-protein-coding RNAs have been identified in recent years. One prominent and complex class of regulatory RNAs is natural antisense transcripts. Mammalian genomes encode numerous natural antisense transcripts, but the function of these transcripts is not well understood. Functional validation studies indicate that antisense transcripts are not a uniform regulatory RNA group, but instead belong to multiple categories with some common features. Recent evidence presented in this book indicates that antisense transcripts are frequently functional and use diverse transcriptional and post- transcriptional gene regulatory mechanisms to carry out a wide variety of biological roles. 128 pp. Englisch.
Lingua: Inglese
Editore: LAP LAMBERT Academic Publishing, 2010
ISBN 10: 3838323947 ISBN 13: 9783838323947
Da: moluna, Greven, Germania
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Aggiungi al carrelloCondizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Faghihi Mohammad AliMohammad Ali Faghihi received his M.D. from the Shiraz University of Medical Sciences, Iran. He received his Ph.D. working with Claes Wahlestedt at Karolinska Institute, Sweden. He then moved to The Scripps Resea.
Lingua: Inglese
Editore: LAP LAMBERT Academic Publishing Sep 2010, 2010
ISBN 10: 3838323947 ISBN 13: 9783838323947
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Natural antisense transcripts: The human genome sequencing projects revealed that the human genome consist of over 3 billion DNA base pairs, but only contain 20,000-25,000 genes that are encoding proteins. Recent studies have revealed that eukaryotic genomes are almost entirely transcribed, generating an enormous number of non-protein-coding RNAs. Several classes of functional non-protein-coding RNAs have been identified in recent years. One prominent and complex class of regulatory RNAs is natural antisense transcripts. Mammalian genomes encode numerous natural antisense transcripts, but the function of these transcripts is not well understood. Functional validation studies indicate that antisense transcripts are not a uniform regulatory RNA group, but instead belong to multiple categories with some common features. Recent evidence presented in this book indicates that antisense transcripts are frequently functional and use diverse transcriptional and post- transcriptional gene regulatory mechanisms to carry out a wide variety of biological roles.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 128 pp. Englisch.
Lingua: Inglese
Editore: LAP LAMBERT Academic Publishing, 2009
ISBN 10: 3838323947 ISBN 13: 9783838323947
Da: AHA-BUCH GmbH, Einbeck, Germania
EUR 59,00
Quantità: 1 disponibili
Aggiungi al carrelloTaschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Natural antisense transcripts: The human genome sequencing projects revealed that the human genome consist of over 3 billion DNA base pairs, but only contain 20,000 25,000 genes that are encoding proteins. Recent studies have revealed that eukaryotic genomes are almost entirely transcribed, generating an enormous number of non-protein-coding RNAs. Several classes of functional non-protein-coding RNAs have been identified in recent years. One prominent and complex class of regulatory RNAs is natural antisense transcripts. Mammalian genomes encode numerous natural antisense transcripts, but the function of these transcripts is not well understood. Functional validation studies indicate that antisense transcripts are not a uniform regulatory RNA group, but instead belong to multiple categories with some common features. Recent evidence presented in this book indicates that antisense transcripts are frequently functional and use diverse transcriptional and post- transcriptional gene regulatory mechanisms to carry out a wide variety of biological roles.