Quantitative structure activity relationship (64 risultati)

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Taschenbuch. Condizione: Neu. QSAR Modeling on Some Anti-Diabetic Analogs | Quantitative Structure Activity Relationship (QSAR) Studies of Some Antidiabetic Analogs | Vaijinath A. Verma | Taschenbuch | Englisch | 2019 | LAP LAMBERT Academic Publishing | EAN 9786200505040 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Condizione: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Diabetes mellitus is a disease in which the body is unable to produce or unable to properly use and store glucose (a form of sugar). Glucose backs up in the bloodstream causing ones blood glucose or "sugar" to raise too high. The diabetes Mellitus having their own historical aspect in 1552 B.C. earliest known of diabetes mentioned on 3rd dynasty Egyptian papyrus by physician mention polyuria (frequent Urination) as a symptom. It has some important landmarks as 1869, German medical student Pual Langerhance discovered that pancreas contains two distinct groups of cells-Acinar cells and islets (cells that are clustered in islands). Quantitative Structure Activity Relationship (QSAR) studies represent the non-experimental part of drug design, including investigation of both structure-activity and structure-property relationship. This is an intellectual exercise comprising assembling, manipulating and inspecting information got from physical, chemical and biological experiments and correlating these to biological activity.…

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Hardcover. Condizione: new. Hardcover. Generally speaking, quantitative-structure activity relationship (QSAR) is a technique which correlates the biological activities of a set of compounds to their structures using a mathematical equation represented in its general form by Biological Activity = f (x1, ., xn), where f is a mathematical function and x1, ., xn are n molecular descriptors. Since the introduction of the initial concept of QSAR in the early 1960s, numerous advances have been introduced into the field transforming it into an essential tool in drug discovery and medicinal chemistry. Quantitative Structure Activity Relationship: A Practical Approach provides a detailed overview of computational approaches in QSAR studies. It covers the applications of different algorithms in various steps of a QSAR analysis and shows clear examples. Each chapter introduces the tools and software involved. Moreover, challenges and issues which may be faced in any step of the analysis are thoroughly broken down based on the OECD guidelines, enabling the reader to familiarize themselves with potential end results. The book was kept concise, making it suitable for students (pharmacy, chemistry and biological science) and lecturers, as well as researchers in the field. Quantitative structureactivity relationship (QSAR) is a computational approach for mathematically connecting structural features of compounds to their biological activities. This unique volume provides the essence of QSAR analysis in a practical manner. It illustrates the basic principles essential for assisting readers in performing analyses. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

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