Formulation, Characterization, and Stability of Protein Drugs: Case Histories: 9 - Rilegato

 
9780306453328: Formulation, Characterization, and Stability of Protein Drugs: Case Histories: 9

Sinossi

Leading scientists offer detailed profiles of ten protein drugs currently in development. An invaluable aid in the rapid identification of potential `hot spots' in proteins, this accessible compilation allows for inspection of the protein's primary structure and preparation of a hydroflex plot.

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Contenuti

A Compendium and Hydropathy/Flexibility Analysis of Common Reactive Sites in Proteins: Reactivity at Asn, Asp, Gin and Met Motifs in Neutral pH Solution; M. Powell. Characterization, Stability, and Formulations of Basic Fibroblast Growth Factor; Y.J. Wang, et al. The Characterization, Stabilization, and Formulation of Acidic Fibroblast Growth Factor; D.B. Volkin, C.R. Middaugh. Stability, Characterization, Formulation, and Delivery System Development for Transforming Growth Factor-Beta1; W.R. Gombotz, et al. Stability and Characterization of Recombinant Human Relaxin; T.H. Nguyen, S.J. Shire. Interferon-£Ii£-1b (Betaserson): A Model for Hydrophobic Therapeutic Proteins; L.S. Lin, et al. Characterization, Formulation, and Stability of Neupogen (Filgrastim): A Recombinant Human Granulocyte Colony Stimulating Factor; A.C. Herman, et al. Development and Shelflife Determination of Recombinant Human Granulocytemacrophage Colonystimulating Factor (Leukin, GMCSF); J. Geigert, B.F.D. Ghrist. Formulation Development of an Antifibrin Monoclonal Antibody Radiopharmaceutical; M. Kamat, et al. Biophysical Characterization and Formulation of TP40: A Chimeric Protein which Requires a pHdependent Conformational Change for Its Biological Activity; G. Sanyal, et al. Stability Characterization and Formulation Development of Recombinant Human Deoxyribonuclease I [Pulmozyme, (Dornase Alpha)]; S.J. Shire. Index.

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9781475770476: Formulation, Characterization, and Stability of Protein Drugs: Case Histories: 9

Edizione in evidenza

ISBN 10:  1475770472 ISBN 13:  9781475770476
Casa editrice: Springer, 2013
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