Adp-Ribosylation in Animal Tissues: Structure, Function, and Biology of Mono (Adp-Ribosyl) Transferases and Related Enzymes: 419 - Rilegato

International Workshop On The Biological Significance Of Mono Adp-ribo

 
9780306455100: Adp-Ribosylation in Animal Tissues: Structure, Function, and Biology of Mono (Adp-Ribosyl) Transferases and Related Enzymes: 419

Sinossi

Documents the first conference on the topic, called in response to opportunities opened by the molecular characterization of the first mammalian mono(ADP-ribosyl)transferase enzyme from rabbit skeletal muscles, and the subsequent realization that one had already been to hand in a well-studied surface membrane protein of T cells, RT6. After introductions to the emerging gene families, the history of ADT- Ribose, and ADP-Ribosylation cycles, the 59 papers cover lessons from procaryotes, molecular approaches to studies in eucaryotes, the enzyme in the immune system and other animal tissues, the physiology of membrane proteins anchored by GPI, NAD+glycohydrolases and ADP-ribosylcyclases, and contemplation of the evolution of the enzyme in the context of the immune system. Appended is a proposal for a unified nomenclature for the relevant vertebrate gene family. Annotation c. by Book News, Inc., Portland, Or.

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Contenuti

Introduction. Mono(ADP-ribosyl)Transferases and Related Enzymes: Emerging Gene Families; F. Koch-Nolte, F. Haag. Mono-ADP-ribosylation in Prokaryotes. Crystal Structure of Diphtheria Toxin Bound to Nicotinamide Adenine Dinucleotide; C.E. Bell, D. Eisenberg. Molecular Approaches to Eukaryotic Mono(ADP-ribosyl)Transferases. Sequence and Structural Links Between Distant ADp-ribosyltransferase Families; F. Bazan, F. Koch-Nolte. Moni(ADP-ribosyl)Transferases in the Immune System. Regulation of Cytotoxic T Cell Functions by a GPI-anchored Ecto-ADP-ribosyltransferase; J. Wang, et al. Mono-ADP-ribosylation in Other Animal Tissues. An ADP-Ribosyltransferase from Bovine Erythrocytes Apparently Specific for Cysteine Residues; S. van Heyningen, B. Saxty. Physiology of GPI-Anchored Proteins. Cell Surface Dynamics of GPI-anchored Proteins; F.R. Maxfield, S. Mayor. Relationship of ADP-Ribosyltransferases to NAD+ Glycohydrolases and ADP-ribosyl Cyclases. ADp-Ribose in Glycation and Glycoxidation Reactions; E.L. Jacobson, et al. Special Lecture Commemorating the Retirement of Professor Heinz-Günter Thiele. Appendix. 28 Additional Lectures. 24 Poster Reports. Index.

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Altre edizioni note dello stesso titolo

9781461346524: ADP-Ribosylation in Animal Tissues: Structure, Function, and Biology of Mono (ADP-ribosyl) Transferases and Related Enzymes: 419

Edizione in evidenza

ISBN 10:  1461346525 ISBN 13:  9781461346524
Casa editrice: Springer, 2012
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