Articoli correlati a Metals and Genetics
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During the past few years, major scientific discoveries have greatly contributed to our understanding of the relationship between metals and genetics. The fields which have contrib uted to this area range from Clinical Medicine and Genetics to Biochemistry and Chemistry. The aim of this book is to bring together investigators from these diverse fields to reflect on the broad implications of direct and indirect interactions of metals and genetic components. The volume begins with a tribute to the late Karen Wetterhahn, an outstanding scien tist in the field, who will be sadly missed by her friends and colleagues because of her un timely death. The book has 28 chapters contributed by scientists who are internationally known for their expertise and outstanding research. The subject matters are divided into five major sections. The first section discusses genetic response to environmental expo sure to metals. Potentially devastating health crises have been reported in recent years from several parts of the world, which stem from environmental exposure to metals. In this section, authors report their findings on the effects and influence of metals in gene ex pression and their consequences to human health. The section on metal carcinogenesis and metal caused DNA damage, presents the latest advances in our knowledge of the molecu lar mechanisms of metal-induced mutagenesis and carcinogenesis. This topic is at the very heart of our understanding of how cancer may be caused by various metals.
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Metals and Genetics
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Condizione: New. In English. Codice articolo ria9780306461019_new
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Metals and Genetics
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Kluwer Academic Publishers Group, 1999
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ISBN 13: 9780306461019
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Metals and Genetics
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Gebunden. Condizione: New. This book covers significant discoveries in the rapidly advancing field of metals and genetics. The aim of this volume is to bring together investigators from diverse fields of clinical medicine, genetics, biochemistry, and chemistry to reflect on the broad. Codice articolo 897689218
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Metals and Genetics
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Buch. Condizione: Neu. Neuware - This book covers significant discoveries in the rapidly advancing field of metals and genetics. The aim of this volume is to bring together investigators from diverse fields of clinical medicine, genetics, biochemistry, and chemistry to reflect on the broad implications of direct and indirect interactions of metals and genetic components. The volume is divided into five sections. The first discusses genetic response to environmental exposure to metals. The section on metal carcinogenesis and metal caused DNA damage presents the latest advances in our knowledge of the molecular mechanisms of metal-induced mutagenis and carcinogenesis. A section is devoted to metals and neurodegenerative diseases. The identification of several disease genes related to metals is a major breakthrough in recent years. The section on genetics and biochemistry of metal-related diseases presents authoritative accounts of current information on both inherited and acquired metal-related diseases. They have discussed the genetics and pathophysiology of these diseases and reported the cloning, expression, purification, and characterization of gene products. Exciting results have been reported recently describing regulation of gene expression by metals. Chapters in this section on metals and gene regulation report recent advances dealing with the mechanism of metal-mediated regulation and control of gene expression. Codice articolo 9780306461019
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