"The science and practice of medicine has undergone a fundamental change as a result of large-scale genome projects that led to the sequencing of a number of important microbial, plant and animal genomes in the last 5 years. This book aims to combine industry standard software engineering and design principles, genomics and bioinformatics and cancer research. It focuses on creating and integrating practical, useful tools for the scientific community in the context of real-life, real-value biomedical problems that researchers face on a routine basis, rather than being just a didactic exercise in learning a programming platform. The book leverages technologies for molecular biology, genomics and bioinformatics and cancer research developed by the NIH, NCI-Center for Bioinformatics (NCICB), the National Center for Biotechnology Information (NCBI, a division of the National Library of Medicine (NLM) at the NIH) and Stanford University."--Publisher.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Java for Bioinformatics and Biomedical Applications describes the work of the U.S. National Cancer Institute (NCI, National Institutes of Health, U.S. Department of Health and Human Services) and a large number of cancer centers across the U.S. under the caBIG (cancer Biomedical Informatics Grid) program, as well as standard bioinformatics applications. The goal of NCI caBIG is to create a standards based, interoperable network of individuals, applications and data to enhance the pace of cancer research. CaBIG uses J2EE and open source standards for all software development work. This book examines the tools and technologies being developed under caBIG to meet the goal of eliminating suffering and death from cancer by 2015 as formulated by the former NCI Director, Dr. Andrew von Eschenbach.In doing so, it provides a vignette into the efforts of thousands of people molecular biologists, medical practitioners, software developers, to name a few - across the country to bring the promise of translational research to individuals with cancer.
From a software perspective, a functional approach is used to teach the Java platform and its features for enterprise-level application development. Under this approach, the various syntactical and operative elements of the language and any software libraries that have been used (for example, BioJava, Apache, etc.) are taught not in isolation but in the context of discrete definable research problems that enable the user to relate how the different parts of the language fit together in the big picture. All examples are derived from practical problems faced in biomedical/clinical data retrieval and analysis during routine bioinformatics and cancer research. Further, the book illustrates how individual bioinformatics applications (such as BLAST and Genscan) can be stitched together into a pipeline so that users can direct the output of one tool (for example, gene predictions using Genscan) to perform further analysis (say, homology searching using BLAST).
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
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Condizione: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions. Codice articolo Z1-U-033-00818
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Condizione: Good. Exact ISBN match. Immediate shipping. No funny business. Codice articolo 9780387372358
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. There are no other books that deal with the topic of J2EE for Bioinformatics or biomedical software development, and no books are available on caBIGae and associated NCI/NCICB technologies such as caCORE and caBIOThere are no other books that d. Codice articolo 5910232
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Medical science and practice have undergone fundamental changes in the last 5 years, as large-scale genome projects have resulted in the sequencing of a number of important microbial, plant and animal genomes. This book aims to combine industry standard software engineering and design principles with genomics, bioinformatics and cancer research. Rather than an exercise in learning a programming platform, the text focuses on useful analytical tools for the scientific community. 364 pp. Englisch. Codice articolo 9780387372358
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
Buch. Condizione: Neu. Neuware -April 2006 Introduction Bioinformatics is at a crossroads. We work in a field that is changing every day, increasingly moving from specific solutions created by single researchers working alone or in small groups to larger, often geographically dispersed programs enabled by collaborative computing and open software. This book represents an important development, giving the reader an opportunity to discover how the use of open and reusable Java code can solve large bioinformatics problems in a software engineered and robust way. I work with one of the authors of this book every day, on the National Cancer Institute's cancer Biomedical Informatics Grid (caBIG¿) project, and I can attest that they are well suited to share with their readers both their experience in the development and use of bioinformatics software, as well as their interest in solid software engineering and interoperability. Background and history In its short history, bioinformatics has become an increasingly important part of how scientists involved in biological research go about their work. This has lead to an explosion of interest in the subject, and a similar explosion in tools and data resources for researchers to learn and use in their work. Historically, tools for bioinformatics have been idiosyncratic and are custom-developed by the end-users (or those close to them) in an iterative fashion until the specific immediate problem is solved. This has led to a balkanization of informatics systems, sometimes yielding multiple, incompatible systems at a single institution for a single application.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 364 pp. Englisch. Codice articolo 9780387372358
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - April 2006 Introduction Bioinformatics is at a crossroads. We work in a field that is changing every day, increasingly moving from specific solutions created by single researchers working alone or in small groups to larger, often geographically dispersed programs enabled by collaborative computing and open software. This book represents an important development, giving the reader an opportunity to discover how the use of open and reusable Java code can solve large bioinformatics problems in a software engineered and robust way. I work with one of the authors of this book every day, on the National Cancer Institute's cancer Biomedical Informatics Grid (caBIG(TM)) project, and I can attest that they are well suited to share with their readers both their experience in the development and use of bioinformatics software, as well as their interest in solid software engineering and interoperability. Background and history In its short history, bioinformatics has become an increasingly important part of how scientists involved in biological research go about their work. This has lead to an explosion of interest in the subject, and a similar explosion in tools and data resources for researchers to learn and use in their work. Historically, tools for bioinformatics have been idiosyncratic and are custom-developed by the end-users (or those close to them) in an iterative fashion until the specific immediate problem is solved. This has led to a balkanization of informatics systems, sometimes yielding multiple, incompatible systems at a single institution for a single application. Codice articolo 9780387372358
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