springer us okt 2006 (45 risultati)

Buch. Condizione: Neu. Neuware - We offer here a non-conventional approach to muhivariate ima- structured data for which the basis is well tested but the analytical ramifi cations are still unfolding. Although we do not formally pursue them, there are several parallels with the nature of neural networks. We employ a systematic set of statistical heuristics for modeling multivariate image data in a quasi-perceptual manner. When the human eye perceives a scene, the elements of the scene are segregated heuristically into compo nents according to similarity and dissimilarity, and then the relationships among the components are interpreted. Similarly, we segregate or seg ment the scene into hierarchically organized components that are subject to subsequent statistical analysis in many modes for interpretive purposes. We refer to the segregated scene segments as patterns, since they provide a basis for perception of pattern. Since they are also hierarchically organ ized, we refer to them further as polypatterns. This leads us to our acro nym of Progressively Segmented Image Modeling As Poly-Patterns (PSIMAPP). Likewise, we formalize our approach in terms of pattern processes and segmentation sequences. In alignment with the terminology of image analysis, we refer to our multivariate measures as being signal bands.

Buch. Condizione: Neu. Neuware - A large number of information systems use many different individual schemas to represent data. Semantically linking these schemas is a necessary precondition to establish interoperability between agents and services. Consequently, ontology alignment and mapping for data integration has becomecentral to building a world-wide semantic web.Ontology Alignment: Bridging the Semantic Gap introduces novel methods and approaches for semantic integration. In addition to developing new methods for ontology alignment, the author provides extensive explanations of up-to-date case studies. The topic of this book, coupled with the application-focused methodology, will appeal to professionals from a number of different domains.Designed for practitioners and researchers in industry, Ontology Alignment: Bridging the Semantic Web Gap is also suitable for advanced-level students in computer science and electrical engineering.

Buch. Condizione: Neu. Neuware - In the last decade, ontologies have received much attention within computer science and related disciplines, most often as the semantic web. Ontology Learning and Population from Text: Algorithms, Evaluation and Applications discusses ontologies for the semantic web, as well as knowledge management, information retrieval, text clustering and classification, as well as natural language processing.Ontology Learning and Population from Text: Algorithms, Evaluation and Applications is structured for research scientists and practitioners in industry. This book is also suitable for graduate-level students in computer science.

Buch. Condizione: Neu. Neuware - Saul Gass has been a leading contributor to the field of Operations Research for more than 50 years. He has been affiliated with the Robert H. Smith School of Business at the University of Maryland for more than 30 years. On February 25, 2006, 'Operations Research in the 21st Century: A Symposium in Honor of Professor Saul Gass' 80th Birthday,' was held on our campus. Opening remarks by Deans Howard Prank and Rudy Lamone were followed by talks by Alfred Blumstein, Karla Hoffman, Richard Larson, Christoph Witzgall, Thomas Magnanti, Rakesh Vohra, and Bruce Golden. The celebration continued into the evening with dinner in the Executive Din ing Room of Van Munching Hall, followed by numerous toasts to Saul. It was a special day for all of us who were in attendance, but it was especially memorable for Saul and his family. This Festschrift companion to the Symposium includes articles from each of the Symposium distinguished speakers plus 16 other articles from friends, colleagues, and several of Saul's former students. The book is divided into three sections. The first section comprises eight articles focusing on the field of Operations Research from a historical or professional perspective. The second section contains nine articles whose theme is optimization and heuristic search, while the third section includes six articles in the general area of modeling and decision making. Collectively, these articles pay tribute to Saul Gass' major interests in the field of Operations Research.

Buch. Condizione: Neu. Neuware - As the world proceeds quickly into the Information Age, it encounters both successes and challenges, and it is well recognized that Intelligent Information Processing provides the key to the Information Age and to mastering many of these challenges. Intelligent Information Processing supports the most advanced productive tools that are said to be able to change human life and the world itself. However, the path is never a straight one and every new technology brings with it a spate of new research problems to be tackled by researchers. As such, the demand for Information Processing research is ever-increasing.This bookpresents the proceedings of the 4th IFIP International Conference on Intelligent Information Processing.This conference provides a forum for engineers and scientists in academia, university and industry to present their latest research findings in all aspects of Intelligent Information Processing.

Buch. Condizione: Neu. Neuware - Latency is a fascinating property of herpesviruses which ensures the maintenance of their genetic information in their hosts for an extended period in the absence of productive virus replication. Focusing on human herpesviruses and animal models of herpesvirus-associated human diseases, this is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion 'tricks' blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation. Latency Strategies of Herpesviruses is an ideal book for researchers, scientists and graduate students in the fields of virology, immunology, microbiology, bacteriology, and veterinary medicine.

Buch. Condizione: Neu. Neuware - Laser ablation describes the interaction of intense optical fields with matter, in which atoms are selectively driven off by thermal or nonthermal mechanisms. The field of laser ablation physics is advancing so rapidly that its principal results are seen only in specialized journals and conferences. This will be the first book that combines the most recent results in this rapidly advancing fieldwith authoritative treatment of laser ablation and its applications, including the physics of high-power laser-matter interaction. Many practical applications exist, ranging from inertial confinement fusion to propulsion of aerostats for pollution monitoring to laser ignition of hypersonic engines to laser cleaning nanoscale contaminants in high-volume computer hard drive manufacture to direct observation of the electronic or dissociative states in atoms and molecules, to studying the properties of materials during 200kbar shocks developed in 200fs.

Buch. Condizione: Neu. Neuware - Semiconductor Modeling: For Simulating Signal, Power, and Electromagnetic Integrity assists engineers - both recent graduates and working product designers - in designing high-speed circuits. The authors apply circuit theory, circuit simulation tools, and practical experience to help the engineer understand semiconductor modeling as applied to high-speed digital designs. The emphasis is on semiconductor modeling, with PCB transmission line effects, equipment enclosure effects, and other modeling issues discussed as needed. The text addresses many practical considerations, including process variation, model accuracy, validation and verification, signal integrity, and design flow. Readers will benefit from its survey of modeling for semiconductors, packages, and interconnects, along with usable advice on how to get complex, high-speed prototypes to work on the first try.Highlights include:- Presents a very complete and well-balanced treatment of modeling of semiconductors, packages, and interconnects. Facilitates reader comprehension of the whole field of high-speed modeling, including digital and RF circuits.- Combines practical modeling techniques with the latest EDA tools for simulation and successful high-speed digital design. Facilitates resolution of practical, every-day problems.- Presents modeling from its historical roots to current state of the art. Facilitates keeping abreast of the latest modeling developments as they continue to unfold.

Buch. Condizione: Neu. Neuware - Stroke is a global health problem affecting approximately 15 million people annually in the world and about 700,000 in the United States. It is the third leading cause of death and the most common cause of disability in most developed countries.Acute Ischemic Injury and Repair in the Nervous System is intended to provide the most up-to-date knowledge of the mechanisms of neuronal death and repair after stroke. It is our belief that this volume of the Handbook of Neurochemistry and Molecular Neurobiology provides an excellent review of the tremendous advances of the past decades in the neurochemical and molecular biological aspects of cerebral ischemia. It is hoped that these advances will provide an impetus for basic scientists and clinicians to further their translational research and to promote the insights for development of therapeutic interventions for stroke.

Buch. Condizione: Neu. Neuware - Lemurs: Ecology and Adaptation brings together information from recent research, and provides new insight into the study of lemur origins, and the ecology and adaptation of both extant and recently extinct lemurs. In addition, it addresses issues of primate behavioral ecology and how environment can play a major role in explaining species variation. Moreover, in a larger context, the information contained in this volume expands our knowledge of primate ecology and allows us further insight into mammalian adaptations to unusual and often harsh environmental conditions that arise from both natural and anthropogenic factors.The book is divided into two sections. The first section is a background to lemurs and their ecology and it includes chapters on origins of lemurs, history of ecological studies on lemurs in Madagascar, theories relating to the evolution of lemur traits, and ecology of the recently extinct (sub-fossil) lemurs. Section two is comprised of chapters focusing on the ecology and adaptations of many species of extant lemurs to the diverse habitats found on Madagascar, and in some cases, adaptations to extreme climatic variability and natural disasters.

Buch. Condizione: Neu. Neuware - From the early examples of what was to be called MRI, extending the te- nique to higher fields than those of less than 0. 1 T used in the first large-volume instruments was a goal, but the way there was unclear. The practical success of large superconducting magnets was a surprise, and the astonishment continued as they developed fields from 0. 3 T to 0. 6 T to 1. 5 T, and even more, up to the now common 3T systems, and a few 4T machines, and now to about 100 times the fields used in the first medium- and large-bore devices. In the early machines, low radiofrequencies of 4 MHz or so meant that RF coil designs were simple (even inexperienced undergraduates could design and build such circuits with little knowledge of more than DC electrical circuits), and the forces on gradient coils were small. The effects of magnetic susceptibility in- mogeneity in and around the object being imaged were negligible, and RF penet- tion depths were not a problem for human-scale samples. Everything began to change as higher fields and higher frequencies came into use, and the earlier idyllic simplicities began to seem quaint. The trend continued, however, driven by the increased signal-to-noise ratios and the resultant higher resolutions and speed available, and sophisticated engineering became more and more essential, not only for magnets but for gradient systems and radiofrequency transmitters and receivers, but also for better software for modeling and correcting distortions.

Buch. Condizione: Neu. Neuware - Shared resources, such as the Internet, have created a highly interconnected cyber-infrastructure. Critical infrastructures in domains such as medical, power, telecommunications, and finance are highly dependent on information systems. These two factors have exposed our critical infrastructures to malicious attacks and accidental failures. Many malicious attacks are achieved by malicious code or malware, such as viruses and worms. Given the deleterious affects of malware on our cyber infrastructure, identifying malicious programs is an important goal. Unfortunately, malware detectors have not kept pace with the evasion techniques commonly used by hackers, i.e., the good guys are falling behind in the arms race.Malware Detection captures the state of the art research in the area of malicious code detection, prevention and mitigation.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Individuals and enterprises are looking for optimal solutions for the problems they face. Most problems can be expressed in mathematical terms, and so the methods of optimization render a significant aid. This book details the latest achievements in optimization. It offers comprehensive coverage on Differential Evolution, presenting revolutionary ideas in population-based optimization and shows the best known metaheuristics through the prism of Differential Evolution. 208 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The most practical and clinical reasons for attempting to understand the immunology of infections and disease revolves around the CD137 and CD137/41BB receptor and ligand molecules. This book covers all aspects of CD137/4-1BB pathway research from microbiology, infectious disease, molecular biology, biochemistry, and genetics to immune responses and potential applications in the diagnosis and treatment of human diseases. This pathway is emerging as one of the most important targets for manipulation of immune responses for disease diagnosis and treatment. This book is written by the man who discovered the CD-137 and B7H1 molecules in 1999. 152 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This atlas examines the benefits and limitations of immunocytochemistry (ICC) in contemporary cytology. The text addresses offers practical advice on choice of markers, and illustrates the use of ICC in fine needle aspiration and body cavity fluid cytology. This practical handbook will allow for quick reference in the selection and interpretation of markers in specific differential diagnostic in the daily practice of diagnostic cytology. Includes 299 color illustrations. 316 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Radio Frequency IDentification (RFID) is an automatic identification method, relying on storing and remotely retrieving data using devices called RFID tags or transponders. An RFID tag is a small object that can be attached toor incorporated into a product, animal or person. An RFID tag contains an antenna to enable it to receive and respond to Radio-Frequency (RF) queries from an RFID reader or interrogator. Passive tags require no internal power source, whereas active tags require a power source.As of today (2006), the concepts of ubiquitous computing and ambient intelligence are becoming widespread. In order for these to become a reality, a number of key technologies are required. In brief, these technologies need to be sensitive, responsive, interconnected, contextualised, transparent and intelligent. RFID, and in particular passive RFID tags, are such a technology. In order to deliver the necessary characteristics that could lead to ambient intelligence, however, there are some challenges that need to be addressed.Remote powering of the tags is probably the most important challenge. Issues concerning the antenna-tag interface and the rectifier design, that allow the RF signal to be converted to Direct Current (DC) are top priorities. Secondly, the communication link and the reader should be optimized. The RF signal that contains the tag data suffers from a power of four decay with the distance between tag and reader. As a result, both the reader sensitivity and the tag backscattered power efficiency have to be maximized. Long-range powering, as well as sufficient communication quality, are the guidelines of this work.This work proposes a linear two-port model for an N-stage modified-Greinacher full wave rectifier. It predicts the overall conversion efficiency at low power levels where the diodes are operating near their threshold voltage. The output electrical behavior of the rectifier is calculated as a function of the received power and the antenna parameters. Moreover, the two-port parameter values are computed for particular input voltages and output currents for the complete N-stage rectifier circuit, using only the measured I-V and C-V characteristics of a single diode.Also presented in this work is an experimental procedure to measure how the impedance modulation at the tag side affects the signal at the reader. The method allows the tag designer to efficiently predict the effect of a modulator design at the system level and gives a useful instrument to choose the most appropriate impedances.Finally, the design of a fully-integrated, remotely powered and addressable RFID tag working at 2.45GHz is described. The achieved operating range at a 4W Effective Isotropically Radiated Power (EIRP) reader transmit power is at most 12 m. The Integrated Circuit (IC) is implemented in a 0.5 um silicon-on-sapphire technology. A state-of-the-art rectifier design is embedded to supply energy to the transponder. Inductive matching and a folded-dipole antenna are key elements for achieving this performance. 148 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is designed to provide insight into the roles of English in and for Europe. The starting point for this comparative study is recognition of the increasing importance of communication with peoples from other cultures and countries. The book contributes to discussions of the possibilities of transnational media offerings, and facilitates a better understanding of the influence of media in foreign language acquisition. 184 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As organizations today are linking their systems across enterprise-wide networks and VPNs as well as increasing their exposure to customers, competitors, browsers and hackers on the Internet, it becomes increasingly imperative for Web professionals to be trained in techniques for effectively protecting their sites from internal and external threats. Each connection magnifies the vulnerability to attack. With the increased connectivity to the Internet and the wide availability of automated cracking tools, organizations can no longer simply rely on operating system security to protect their valuable corporate data. Furthermore, the exploding use of Web technologies for corporate intranets and Internet sites has escalated security risks to corporate data and information systems.Practical Internet Security reveals how the Internet is paving the way for secure communications within organizations and on the public Internet. This book provides the fundamental knowledge needed to analyze risks to a system and to implement a security policy that protects information assets from potential intrusion, damage, or theft. It provides dozens of real-life scenarios and examples, as well as hands-on instruction in securing Web communications and sites. You will learn the common vulnerabilities of Web sites; as well as, how to carry out secure communications across unsecured networks. All system administrators and IT security managers will find this book an essential practical resource. 560 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Computational and Instrumental Methods in EPR is devoted to both instrumentation and computation aspects of EPR, while addressing applications such as spin relaxation time measurements. However, this is the first comprehensive volume to offer practical, non-invasive spectroscopic methods of analyzing the rheology of biopolymers: comparative studies of polymer fluidity using traditional methods (e.g. viscosity) and nuclear magnetic resonance. 232 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book offers an autobiographical reflexive approach to foreign language education. It offers unique ways of developing vocational language teaching as an integrated holistic approach combining language contents with vocationally relevant topics and the interactive, dialogical processes of working in language classes. It is presented in a 'common sense' way and accessible to non-native English readers. 248 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is an original and comprehensive examination of brewing from the perspective of a real brewer. The book departs from the traditional sequential approach to pursue brewing in the manner a brew master approaches the process. It is structured to look down the length of the process for causes and effects. Each essay discusses a problem, a beer component, or a flavor, by following how this one item arises and how it changes along the way. This is a crucial feature to bear in mind when reading the book because this organization brings together information and ideas that are not usually presented side-by-side. 192 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Customer-Oriented Optimization in Public Transportation develops models, results and algorithms for optimizing public transportation from a customer-oriented point of view. The methods used are based on graph-theoretic approaches and integer programming. The specific topics are all motivated by real-world examples which occurred in practical projects. An appendix summarizes some of the basics of optimization needed to interpret the material in the book.In detail, the topics the book covers in its three parts are as follows:1. Stop location. Does it make sense to open new stations along existing bus or railway lines If yes, in which locations The problem is modeled as a continuous covering problem. To solve it the author develops a finite dominating set and shows that efficient methods are possible if the special structure of the covering matrix is used.2. Delay management. Should a train wait for delayed feeder trains or should it depart in time The author builds up two different integer programming models and a model based on project planning methods. Properties and solution methods are developed.3. Tariff planning. Part 3 deals with the design of zone tariff systems, in which the fare is determined by the number of zones used by the passengers. The author presents a model for this problem and approaches based on clustering theory. 284 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The discipline of landscape ecology has matured rapidly over the past few decades, generating a wealth of knowledge that can be used to enhance forest policy development and management. However, much of this knowledge has yet to be applied in practice.Forest Landscape Ecology: Transferring Knowledge to Practice is the first book to introduce landscape ecologists to the discipline of knowledge transfer. The book considers knowledge transfer in general, critically examines aspects of transfer that are unique to forest landscape ecology, and reviews several case studies of successful applications for policy developers and forest managers in North America. Readers are encouraged to recognize the value of sharing their knowledge, and to understand their role in active knowledge transfer. The intent is to connect, as seamlessly and effectively as possible, ecological principles to policy and practice.This book is written for researchers, academics and students in landscape ecology and related fields, as well as policymakers and land and resource managers who are interested in landscape-level approaches. The discipline of landscape ecology has matured rapidly over the past few decades, generating a wealth of knowledge that can be used to enhance forest policy development and management. However, much of this knowledge has yet to be applied in practice.'Forest Landscape Ecology: Transferring Knowledge to Practice' is the first book to introduce landscape ecologists to the discipline of knowledge transfer. The book considers knowledge transfer in general, critically examines aspects of transfer that are unique to forest landscape ecology, and reviews several case studies of successful applications for policy developers and forest managers in North America. Readers are encouraged to recognize the value of sharing their knowledge, and to understand their role in active knowledge transfer. The intent is to connect, as seamlessly and effectively as possible, ecological principles to policy and practice.This book is written for researchers, academics and students in landscape ecology and related fields, as well as policymakers and land and resource managers who are interested in landscape-level approaches. 240 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In recent years, cytology has played an increasingly important role in the diagnosis of disease, particularly those of neoplastic origin. It is not unusual for cytologic specimens to be the only diagnostic samples available from patients with cancer. Many ancillary tests traditionally performed on histologic material are now being performed on cytologic specimens. One such technique, immunocytochemistry (ICC), has already proved to be important in diagnostic tumor pathology.This atlas examines the value of ICC as well as its limitations in contemporary cytology. Methods have been refined and high-quality reagents are now available. As a result, technical problems no longer present a major concern in this field. This volume will briefly address the technical aspects of ICC by providing practical advice for the users and analytical aspects of ICC, including correct selection of markers for specific differential diagnoses and incorporation of results in final cytologic interpretation; illustrate the utilization of ICC in the resolution of some common diagnostic problems in fine needle aspiration and body cavity fluid cytology. ICC of undifferentiated malignant neoplasms, carcinomas of unknown origin, and most importantly its utilization in specific differential diagnoses that are based on cytomorpholoy and patient¿s clinical history is also discussed. This practical handbook will allow for quick reference in the selection and interpretation of markers in specific differential diagnostic in the daily practice of diagnostic cytology.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 316 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -It is still hard to believe that manipulation of a single protein on the cell surface or an interaction of two or more proteins, which at times is collectively referred to as a ¿pathway,¿ could have such a profound effect on our immune system. At present, a number of such proteins or pathways have been identi ed. These observations could only be interpreted in a way that, although tens of thousand of proteins are required for a perfectly healthy immune system, many of these pathways may work in either interconnected or linear fashion. Therefore, the combined understanding of each pathway, their interactions with other pathways, and the functional c- sequence, is a cornerstone for our interpretation of pathological basis of diseases and future treatments. It is important to stay abreast on the pace of progress, which I refer to as periodic summary of incremental and breakthrough discoveries in each pathway by the experts and the leader in the eld. The CD137 Pathway: Immunology and Diseases represents such an effort and this is the rst attempt to summarize our understanding of the CD137 pathway. The following chapters cover the majority of active areas of research in this pathway and also provide an essential resource to both the nonexperts and experts in the eld.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 148 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book will help readers to better manage supply chains in emerging economics. It addresses a host of issues and challenges, from infrastructure constraints and the logistics inefficiencies to contributing to the social and environmental developments of emerging economies. Innovative approaches are outlined and illustrated with examples of real-world experiences by progressive companies and thought leaders. 488 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is the second of two volumes addressing the design challenges associated with new generations of semiconductor technology. The various chapters are compiled from tutorials presented at workshops in recent years by prominent authors from all over the world. Technology, productivity and quality are the main aspects under consideration to establish the major requirements for the design and test of upcoming systems on a chip. 244 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -he hedgehog signalling pathway is highly conserved and seen in organisms ranging from Drosophila to humans. This pathway is Tcritical in determining cell fate decisions in a variety of different cell types. There are several vertebrate analogues of the Drosophila hedgehog protein of which the most widely studied is Sonic hedgehog (Shh). Shh signalling classically involves the Gli family of zinc-fmger transcription factors. The Shh signalling pathway is well characterised in the develop ment of a number of vertebrate organ systems. It could indeed be argued that the Shh and Gli signalling may well be involved at some stage in the development of all the major organ systems in vertebrates. This volume rep resents a concerted drive to bring together \*state of the art' reviews by lead ing experts in the field of Shh and Gli signalling in development from all over the world. The chapters span vertebrate organisms from zebrafish to humans and cover development of the multiple organ systems in which the Shh signalling pathway is crucial for normal development. There are chap ters on the development of the central nervous system, skeletal struc tures, visceral organs, prostate, lung, immune system and the structures of the human face. The authors themselves span three major continents and multiple nationalities which admirably illustrates the worldwide nature of the science. 172 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents a new method for assessing spatial pattern in raster land cover maps based on satellite imagery in a way that incorporates multiple pixel resolutions. This is combined with more conventional single-resolution measurements of spatial pattern and simple non-spatial land cover proportions to assess predictability of both surface water quality and ecological integrity within watersheds of the state of Pennsylvania (USA). 152 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Medical science and practice have undergone fundamental changes in the last 5 years, as large-scale genome projects have resulted in the sequencing of a number of important microbial, plant and animal genomes. This book aims to combine industry standard software engineering and design principles with genomics, bioinformatics and cancer research. Rather than an exercise in learning a programming platform, the text focuses on useful analytical tools for the scientific community. 364 pp. Englisch.