Articoli correlati a Evolving Methods for Macromolecular Crystallography:...
Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanisms of Action of CBRN Agents: The ... the Mechanism of Action of CBRN Agents: 245 - Rilegato
This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems.
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"The book is a summary of the proceedings on ‘Evolving Methods for Macromolecular Crystallography’ held in 2005. ... it is a welcome addition to the crystallographer’s bookshelf with contributions by a number of experts in their field." (Miroslav Papiz, Crystallography Reviews, Vol. 15 (2), 2009)
Preface. Succeeding with Seeding: some practical Advice; T. Bergfors.- Expression, Purification and Crystallisation of membrane Proteins; Bernadette Byrne.- Macromolecular Cryo-Crystallography; E. Garinan.- Processing Diffraction Data with Mosfim; A.G. W. Leslie and H.R. Powell.- SAD Phasing: basic Concepts and High-Throughput; G.M. Sheldrick.- Likelihood-based experimental phasing in Phaser; A.J. McCoy, L. C. Storoni and R. J. Read.- Stochastic molecular Replacement; N. M. Glykos.- Likelihood-based molecular Replacement in Phaser; R. J. Read et al.- Automated Structure Determination with PHENIX ; P. D. Adam et al.- Density Modification in MAIN; D. Turk.- Ab initio Phasing starting from Low Resolution; V.Lunin et al. Structural Genomics of Mycobacterium tuberculosis - a Search for Function and new Drug Targets; T. Baker.- 3D Domain Swapping and its Relevance to conformational Diseases; M. Jaskolski.- Structural Bioinformatics: From PROTEIN Structure to Function; J.D. Watson et al.- Single-particle Imaging; D. Sayre.-
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- EditoreSpringer Nature
- Data di pubblicazione2007
- ISBN 10 1402063148
- ISBN 13 9781402063145
- RilegaturaCopertina rigida
- Numero edizione1
- Numero di pagine191
- RedattoreRead Randy J., Sussman Joel L.
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Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents
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Descrizione libro Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume draws on the expertise of leaders in the field of macromolecular crystallography to illuminate the dramatic developments that are accelerating progress in structural biology. Their contributions span the range of techniques from crystallization through data collection, structure solution and analysis. The book shows how modern high-throughput methods are contributing to a deeper understanding of medical problems. 192 pp. Englisch. Codice articolo 9781402063145
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Descrizione libro Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the NATO Advanced Study Institute on Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of CBRN agents, Erice, Italy, 19-28 May 2005|Arises from the renowned Erice Schoo. Codice articolo 4094474
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Descrizione libro Condizione: New. pp. 200. Codice articolo 26472223
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Evolving Methods for Macromolecular Crystallography : The Structural Path to the Understanding of the Mechanism of Action of Cbrn Agents
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Descrizione libro Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume comprises papers presented at the 2005 edition of the 'Crystallography of Molecular Biology' courses that have been held since 1976 at the Ettore Majorana Centre for Scientific Culture in Erice, Italy. This series of courses is renowned for bringing leaders in the field of macromo- cular crystallography together with highly motivated students, in a beautiful and intimate location that encourages people to interact. The warm and informal atmosphere at these Erice conferences, especially these on cryst- lography, has helped to foster long-term scientific interactions and new int- national friendships that have often lasted for the lifetime of the scientists. The course was financed by NATO as an Advanced Study Institute and by the European Commission as a EuroSummerSchool. The papers span the breadth of material presented in the course, which emphasized the practical aspects of modern macromolecular crystallography and its applications. One must start with crystals: Bergfors showed how to improve initial crystals through seeding, while Byrne discussed the difficult problem of crystallizing membrane proteins. The collection of optimal diffraction data requires both careful preparation of cryo-cooled crystals (Garman) and proper processing of the diffraction images (Leslie). To obtain images of electron density, one needs estimates of the phases of the diffracted spots. Sheldrick presented the background to the sing- wavelength anomalous diffraction (SAD) method, which has been gaining popularity, and McCoy discussed the basis of modern maximum likelihood methods for treating information in experimental phasing. Codice articolo 9781402063145
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Descrizione libro Condizione: New. pp. 200 Illus. Codice articolo 7375680
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Descrizione libro Condizione: New. Proceedings of the NATO Advanced Study Institute on Evolving Methods for Macromolecular Crystallography: The Structural Path to the Understanding of the Mechanism of Action of CBRN agents, Erice, Italy, 19-28 May 2005 Editor(s): Read, Randy J.; Sussman, Joel L. Series: NATO Science Series II. Num Pages: 200 pages, biography. BIC Classification: PNT. Category: (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 12. Weight in Grams: 459. . 2007. Hardback. . . . . Codice articolo V9781402063145
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