Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis - Rilegato

 
9781402073700: Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis
Rilegato
ISBN 10: 1402073704 ISBN 13: 9781402073700
Casa editrice: Kluwer Academic Pub, 2003

Sinossi

It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages.

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Contenuti

Contributors. Preface. 1. Introduction; G.G. Harrigan, R. Goodacre. 2. Metabolome and Proteome Profiling for Microbial Characterization; S. Vaidyanathan, R. Goodacre. 3. Can 1H NMR Derived Metabolic Profiles Contribute to Proteomic Analyses? J.L. Griffin, E. Sang. 4. Application of Metabonomics in the Pharmaceutical Industry; A.P. Breau, G.H. Cantor. 5. Metabolic Profiling in Tumors by in Vivo and in Vitro NMR Spectroscopy; Yeun-Li Chung, M. Stubbs, J. Griffiths. 6. Raman Spectroscopy for Whole Organism and Tissue Profiling; S. Clarke, R. Goodacre. 7. Metabolic Fingerprinting with Fourier Transform Infrared Spectroscopy; D.I. Ellis, G.G. Harrigan, R. Goodacre. 8. Metabolomic Analysis with with Fourier Transform Ion Cyclotron Resonance Mass Spectroscopy; D. Goodenowe. 9. Stable Isotope-Based Dynamic Metabolic Profiling in Disease and Health; L.G. Boros, M. Cascante, W.-N.P. Lee. 10. The role of Metabolomics in Systems Biology; J.van der Greef, E. Davidov, E. Verheij, J. Vogels, R.van der Heijden, A.S. Adourian, M. Oresic, E.W. Marple, S. Naylor. 11. Use of Metabolomics to Discover Metabolic Patterns Associated with Human Diseases; O. Fiehn, J. Spranger. 12. Bioactive Lipids in Reproductive Diseases; J. Chaudhary, T. Compton, J.A. Parrott. 13. Evolutionary Computation for the Interpretation of Metabolomic Data; R. Goodacre, D.B. Kell. 14. Dynamic Profiling and Canonical Modeling; E.O. Voit, J. Almeida. 15. Databases, Data Modeling and Schemas; N. Hardy, H. Fuell. 16. Databases and Visualization for Metabolomics; X. Jing Lee, O. Brazhnik, A. Kamal, D. Guo, C. Lee, S. Hoops, P. Mendes. 17. The Human Metabolome. C.W.W. Beecher. Index.

Product Description

Rare book

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Editore
Kluwer Academic Pub
Data di pubblicazione
2003
Lingua
Inglese
ISBN 10 
1402073704
ISBN 13 
9781402073700
Rilegatura
Copertina rigida
Numero di pagine
335
Redattore
Harrigan George G., Goodacre Royston
Contatto del produttore
non disponibile
Persona responsabile
CMN Printpool Inh. Mathis Neumann
https://www.also.com/ec/cms5/en_6000/6000/index.jsp

Friedrich-Karl-Str. 9
Hamburg
Germania

Altre edizioni note dello stesso titolo

9781461350255: Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis

Edizione in evidenza

ISBN 10:  1461350255 ISBN 13:  9781461350255
Casa editrice: Springer, 2012
Brossura