Basics of PET Imaging: Physics, Chemistry, and Regulations - Rilegato

Saha, Gopal B.

Rilegato

ISBN 10: 1441908048 ISBN 13: 9781441908049

Casa editrice: Springer Nature, 2010

Riassunto

ofeachchapter,asappropriate,tore?ectthechangesincontents. IthankmycolleaguesattheClevelandClinicFoundationfortheirsupport in manywaysand Mrs. DianeGrif?s for kindly typingand completingthe manuscriptontime. vii viii Preface IsincerelythankAndrewMoyer,editorofradiologyandnuclearmedicine, atSpringerforsupportandencouragement,andS. GeethalakshmiSrinivasan, ProjectManager,atSPiTechnologiesIndiaPvtLtdforexcellentproduction ofthebook. Cleveland,OH GopalB. Saha Contents 1. RadioactiveDecayandInteractionofRadiationwithMatter . . . 1 AtomicStructure . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 RadioactiveDecay . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 ?Decay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 ? ? Decay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 + Positron(?)Decay . . . . . . . . . . . . . . . . . . . . . . . . . 3 ElectronCapture . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 IsomericTransition . . . . . . . . . . . . . . . . . . . . . . . . . . 4 RadioactiveDecayEquations . . . . . . . . . . . . . . . . . . . . . 5 GeneralDecayEquations . . . . . . . . . . . . . . . . . . . . . . 5 SuccessiveDecayEquations . . . . . . . . . . . . . . . . . . . . . 7 UnitsofRadioactivity . . . . . . . . . . . . . . . . . . . . . . . . 9 UnitsofRadioactivityinSystemInternationale . . . . . . . . . 9 Calculations . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 InteractionofRadiationwithMatter . . . . . . . . . . . . . . . . . 10 InteractionofChargedParticleswithMatter . . . . . . . . . . . 10 Interactionof?RadiationwithMatter . . . . . . . . . . . . . . 12 Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 ReferencesandSuggestedReading . . . . . . . . . . . . . . . . 17 2. PET ScanningSystems . . . . . . . . . . . . . . . . . . . . . . . . . 19 Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 SolidScintillationDetectorsinPET . . . . . . . . . . . . . . . . . 20 PhotomultiplierTube . . . . . . . . . . . . . . . . . . . . . . . . . . 24 PulseHeightAnalyzer . . . . . . . . . . . . . . . . . . . . . . . . . 25 ArrangementofDetectors . . . . . . . . . . . . . . . . . . . . . . 25 PETScanners . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 CoincidenceScintillationCameras . . . . . . . . . . . . . . . . . . 29 PET/CTScanners . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 SmallAnimalPETScanner . . . . . . . . . . . . . . . . . . . . . . 33 MobilePETorPET/CT . . . . . . . . . . . . . . . . . . . . . . . . 36 ix x Contents Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 38 ReferencesandSuggestedReading . . . . . . . . . . . . . . . . 39 3. DataAcquisition and Corrections . . . . . . . . . . . . . . . . . . . 41 PETDataAcquisition . . . . . . . . . . . . . . . . . . . . . . . . . . 41 TimeofFlightMethod . . . . . . . . . . . . . . . . . . . . . . . . 46 Two-Dimensionalvs. Three-Dimensional DataAcquisition . . . . . . . . . . . . . . . . . . . . . . . . 47 FactorsAffectingAcquiredPETData . . . . . . . . . . . . . . . . 49 Normalization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49 PhotonAttenuation . . . . . . . . . . . . . . . . . . . . . . . . . 50 AttenuationCorrectionMethods . . . . . . . . . . . . . . . . . . 52 RandomCoincidences . . . . . . . . . . . . . . . . . . . . . . . . 53 ScatterCoincidences . . . . . . . . . . . . . . . . . . . . . . . . . 55 CorrectionforScatterCoincidences . . . . . . . . . . . . . . . . 56 DeadTime . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 58 RadialElongation . . . . . . . . . . . . . . . . . . . . . . . . . . 59 PET/CTDataAcquisition . . . . . . . . . . . . . . . . . . . . . . . 60 FactorsAffectingPET/CTData . . . . . . . . . . . . . . . . . . 62 Questions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 ReferencesandSuggestedReading . . . . . . . . . . . . .

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This revised edition of Basics of PET Imaging presents an unparalleled text on the basics of PET imaging technology. Distinguished author, Dr. Gopal B. Saha, has updated his previous bestselling work with concise chapters on PET fundamentals, including:

• Basic physics

• Instrumentation and data acquisition

• Production of PET radionuclides

• Performance characteristics of PET scanners

• Regulatory and reimbursement issues

To maximize understanding, and to help technologists and residents prepare for board exams, chapters include pertinent basic science and equations along with sample problems and practice questions. The remarkable combination of Dr. Saha s brevity and clarity of content once again makes this edition an ideal reference book for nuclear medicine professionals interested in the basics of PET imaging.

Dettagli dell'edizione

• Editore: Springer Nature
• Data di pubblicazione: 2010
• Lingua: Inglese
• ISBN 10: 1441908048
• ISBN 13: 9781441908049
• Rilegatura: Copertina rigida
• Numero edizione: 2
• Numero di pagine: 241
• Contatto del produttore: non disponibile
• Persona responsabile: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Germania