Articoli correlati a Oncogenes as Transcriptional Regulators: Cell Cycle...
Oncogenes as Transcriptional Regulators: Cell Cycle Regulators and Chromosomal Translocation - Brossura
Sinossi
The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes.
Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.
Contenuti
1 E2Fs and the Retinoblastoma Protein Family.- 2 Signalling to the C-terminus of p53.- 3 Chromosome Translocations Generating Chimeric Transcription Factors, Unique Genetic Events with Pleiotropic Cellular Consequences.- 4 The Runt Domain Transcription Factor, PEBP2/CBF, and its Involvement in Human Leukemia.- 5 EBNA2: A Viral Transcription Factor Essential for the Immortalization of Human B Lymphocytes by the Epstein-Barr Virus (EBV).
Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.
Compra nuovo
Visualizza questo articolo
EUR 48,37
EUR 9,70 per la spedizione da Germania a Italia
Destinazione, tempi e costi
Risultati della ricerca per Oncogenes as Transcriptional Regulators: Cell Cycle...
Immagini fornite dal venditore
Oncogenes as Transcriptional Regulators
Print on DemandDa: moluna, Greven, Germania
Valutazione del venditore 5 su 5 stelle
Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes c. Codice articolo 4319640
Quantità: Più di 20 disponibili
Foto dell'editore
Oncogenes as Transcriptional Regulators: Cell Cycle Regulators and Chromosomal Translocation (Progress in Gene Expression)
Da: BOOKWEST, Phoenix, AZ, U.S.A.
Valutazione del venditore 3 su 5 stelle
Soft cover. Condizione: New. NEW: SHRINK-WRAPPED: US SELLER SHIPS FAST FROM USA. Codice articolo INT2-146B8-3764357096-HC-1Pt6-B22
Quantità: 1 disponibili
Immagini fornite dal venditore
Oncogenes as Transcriptional Regulators
Editore:
Birkhäuser Basel Okt 2012, 2012
ISBN 10: 3034898339
ISBN 13: 9783034898331
Nuovo
Taschenbuch
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes. 180 pp. Englisch. Codice articolo 9783034898331
Quantità: 2 disponibili
Immagini fornite dal venditore
Oncogenes as Transcriptional Regulators : Cell Cycle Regulators and Chromosomal Translocation
Da: AHA-BUCH GmbH, Einbeck, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes. Codice articolo 9783034898331
Quantità: 1 disponibili
Immagini fornite dal venditore
Oncogenes as Transcriptional Regulators
Editore:
Birkhäuser Basel, Springer Basel Okt 2012, 2012
ISBN 10: 3034898339
ISBN 13: 9783034898331
Nuovo
Taschenbuch
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
Valutazione del venditore 5 su 5 stelle
Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The intensive study of molecular events leading to cellular transformation in tissue culture or in intact organisms culminated in the identification of 100 or more genes that can be defined as oncogenes or tumor suppressor genes. Functionally, these genes can be divided into several classes, each involved in a different step in transmission of signals from the exterior of the cell to the nucleus. The first oncogenes to be biochemically character ized included membrane receptors for growth factors, growth factors themselves, protein kinases or small GTP binding proteins involved in signal transduction. Later, the development of techniques to study pro teins-DNA interaction in eucaryotes and the isolation and characterization of many promoter and enhancer sequences revealed that a number of the classical retroviral oncogenes were indeed transcription factors. In paral lel, the rapid progress in the identification and cloning of chromosomal translocations in human and animal malignancies and the increased reper toire of known transcription factors families revealed that many other transcription factors can playa critical role in cancer. A more recent devel opment concerns tumor suppressor genes. The realization that human tumors are frequently associated with a loss of function of one or several genes is also one of the landmarks of cancer research in the last 15 years. Again, as we will see below, some of these genes encode transcription factors. It is becoming increasingly difficult to cover in a single monograph all oncogenes and tumor suppressor genes.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 180 pp. Englisch. Codice articolo 9783034898331
Quantità: 1 disponibili
Foto dell'editore
Oncogenes as Transcriptional Regulators: Cell Cycle Regulators and Chromosomal Translocation (Progress in Gene Expression)
Da: Ria Christie Collections, Uxbridge, Regno Unito
Valutazione del venditore 5 su 5 stelle
Condizione: New. In. Codice articolo ria9783034898331_new
Quantità: Più di 20 disponibili
Foto dell'editore
Oncogenes as Transcriptional Regulators: Volume 2 (Progress in Gene Expression)
Da: Chiron Media, Wallingford, Regno Unito
Valutazione del venditore 4 su 5 stelle
Paperback. Condizione: New. Codice articolo 6666-IUK-9783034898331
Quantità: 10 disponibili
Foto dell'editore
Oncogenes as Transcriptional Regulators
Da: Books Puddle, New York, NY, U.S.A.
Valutazione del venditore 4 su 5 stelle
Condizione: New. pp. 180. Codice articolo 2698253314
Quantità: 4 disponibili
Foto dell'editore
Oncogenes as Transcriptional Regulators
Print on DemandDa: Biblios, Frankfurt am main, HESSE, Germania
Valutazione del venditore 5 su 5 stelle
Condizione: New. PRINT ON DEMAND pp. 180. Codice articolo 1898253320
Quantità: 4 disponibili
Foto dell'editore
Oncogenes as Transcriptional Regulators
Print on DemandDa: Majestic Books, Hounslow, Regno Unito
Valutazione del venditore 5 su 5 stelle
Condizione: New. Print on Demand pp. 180 49:B&W 6.14 x 9.21 in or 234 x 156 mm (Royal 8vo) Perfect Bound on White w/Gloss Lam. Codice articolo 95192541
Quantità: 4 disponibili