Sinossi
The chemistry of macrolides (i.e. macrolides antibiotics) originated in 1926 with the initial discovery of macrocyclic compounds such as civetone and muscone by Ruzicka. Kershbaum demonstrated for the first time the presence of large ring lactones in exaltolide and ambrettolide. Many of the macrolides shows antibiotic nature and they play a therapeutically important role in pathology. They are regarded as among the safest of antibiotics and they have successfully been used to treat infections caused by grampositive organisms and certain gram-negative and anaerobic bacteria. The interesting biological properties of medium-sized ring systems tend to attract the scientists from worldwide toward the synthesis of macrolides. In this book we explained the stereoselective total synthesis of (-) - Cephalosporolide D, Verbalactone and (-) - Pyrenophorol from commercially available starting materials (S)-propylene epoxide, D-mannitol and (S)-propylene epoxide. The key steps involved in theses syntheses are Grignard reaction, Noyori asymmetric reduction, Yamaguchi macrolactonization, Barbier allylation, Swern oxidation, Wittig reaction and Mitsunobu cyclization etc.
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Synthesis of (-)¿Cephalosporolide D,Verbalactone and (-) -Pyrenophorol
Editore:
LAP LAMBERT Academic Publishing Jul 2018, 2018
ISBN 10: 3330335238
ISBN 13: 9783330335233
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The chemistry of macrolides (i.e. macrolides antibiotics) originated in 1926 with the initial discovery of macrocyclic compounds such as civetone and muscone by Ruzicka. Kershbaum demonstrated for the first time the presence of large ring lactones in exaltolide and ambrettolide. Many of the macrolides shows antibiotic nature and they play a therapeutically important role in pathology. They are regarded as among the safest of antibiotics and they have successfully been used to treat infections caused by grampositive organisms and certain gram-negative and anaerobic bacteria. The interesting biological properties of medium-sized ring systems tend to attract the scientists from worldwide toward the synthesis of macrolides. In this book we explained the stereoselective total synthesis of (-) - Cephalosporolide D, Verbalactone and (-) - Pyrenophorol from commercially available starting materials (S)-propylene epoxide, D-mannitol and (S)-propylene epoxide. The key steps involved in theses syntheses are Grignard reaction, Noyori asymmetric reduction, Yamaguchi macrolactonization, Barbier allylation, Swern oxidation, Wittig reaction and Mitsunobu cyclization etc. 132 pp. Englisch. Codice articolo 9783330335233
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Synthesis of (-)-Cephalosporolide D,Verbalactone and (-) -Pyrenophorol
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LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3330335238
ISBN 13: 9783330335233
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Alluraiah GurralaDr. G. Alluraiah recieved his B.Sc, M.Sc, M.Phil and Ph.D degrees from Acharya Nagarjuna University, Nagarjuna Nagar, Andhra Pradesh, India. He currently working as HoD, Department of Chemistry, S.V. Arts & Science C. Codice articolo 385708543
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Synthesis of (-)Cephalosporolide D,Verbalactone and (-) -Pyrenophorol
Editore:
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3330335238
ISBN 13: 9783330335233
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Paperback. Condizione: Brand New. 132 pages. 8.66x5.91x0.30 inches. In Stock. Codice articolo 3330335238
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Synthesis of (-)-Cephalosporolide D,Verbalactone and (-) -Pyrenophorol
Editore:
LAP LAMBERT Academic Publishing Jul 2018, 2018
ISBN 10: 3330335238
ISBN 13: 9783330335233
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germania
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The chemistry of macrolides (i.e. macrolides antibiotics) originated in 1926 with the initial discovery of macrocyclic compounds such as civetone and muscone by Ruzicka. Kershbaum demonstrated for the first time the presence of large ring lactones in exaltolide and ambrettolide. Many of the macrolides shows antibiotic nature and they play a therapeutically important role in pathology. They are regarded as among the safest of antibiotics and they have successfully been used to treat infections caused by grampositive organisms and certain gram-negative and anaerobic bacteria. The interesting biological properties of medium-sized ring systems tend to attract the scientists from worldwide toward the synthesis of macrolides. In this book we explained the stereoselective total synthesis of (-) - Cephalosporolide D, Verbalactone and (-) - Pyrenophorol from commercially available starting materials (S)-propylene epoxide, D-mannitol and (S)-propylene epoxide. The key steps involved in theses syntheses are Grignard reaction, Noyori asymmetric reduction, Yamaguchi macrolactonization, Barbier allylation, Swern oxidation, Wittig reaction and Mitsunobu cyclization etc.Books on Demand GmbH, Überseering 33, 22297 Hamburg 132 pp. Englisch. Codice articolo 9783330335233
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Synthesis of (-)¿Cephalosporolide D,Verbalactone and (-) -Pyrenophorol
Editore:
LAP LAMBERT Academic Publishing, 2018
ISBN 10: 3330335238
ISBN 13: 9783330335233
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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The chemistry of macrolides (i.e. macrolides antibiotics) originated in 1926 with the initial discovery of macrocyclic compounds such as civetone and muscone by Ruzicka. Kershbaum demonstrated for the first time the presence of large ring lactones in exaltolide and ambrettolide. Many of the macrolides shows antibiotic nature and they play a therapeutically important role in pathology. They are regarded as among the safest of antibiotics and they have successfully been used to treat infections caused by grampositive organisms and certain gram-negative and anaerobic bacteria. The interesting biological properties of medium-sized ring systems tend to attract the scientists from worldwide toward the synthesis of macrolides. In this book we explained the stereoselective total synthesis of (-) - Cephalosporolide D, Verbalactone and (-) - Pyrenophorol from commercially available starting materials (S)-propylene epoxide, D-mannitol and (S)-propylene epoxide. The key steps involved in theses syntheses are Grignard reaction, Noyori asymmetric reduction, Yamaguchi macrolactonization, Barbier allylation, Swern oxidation, Wittig reaction and Mitsunobu cyclization etc. Codice articolo 9783330335233
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