Cross-Coupling Reactions: A Practical Guide: 219 - Rilegato

Rilegato

ISBN 10: 3540421750 ISBN 13: 9783540421757

Casa editrice: Springer Verlag, 2002

Riassunto

In 1972, a very powerful catalytic cycle for carbon-carbon bond formation was 2 first discovered by the coupling reaction of Grignard reagents at the sp -carbon. Over the past 30 years, the protocol has been substantially improved and expanded to other coupling reactions of Li,B,N,O,Al,Si,P,S,Cu,Mn,Zn,In,Sn, and Hg compounds. These reactions provided an indispensable and simple methodology for preparative organic chemists. Due to the simplicity and rel- bility in the carbon-carbon, carbon-heteroatom, and carbon-metalloid bo- formations,as well as high efficiency of the catalytic process,the reactions have been widely employed by organic chemists in various fields. Application of the protocol ranges from various syntheses of complex natural products to the preparation of biologically relevant molecules including drugs, and of sup- molecules, and to functional materials. The reactions on solid surfaces allow robot synthesis and combinatorial synthesis. Now, many organic chemists do not hesitate to use transition metal complexes for the transformation of org- ic molecules. Indeed, innumerable organic syntheses have been realized by the catalyzed reactions of transition metal complexes that are not achievable by t- ditional synthetic methods. Among these, the metal-catalyzed cross-coupling reactions have undoubtedly contributed greatly to the development of such a new area of metal-catalyzed organic syntheses . An excellent monograph for the cross-coupling reactions and other met- catalyzed C-C bond-forming reactions recently appeared in Metal-catalyzed Cross-coupling Reactions (Wiley-VCH,1998).

Su questo libro

Recensione

 

It is also suitable for teaching advanced courses in organic and organometallic chemistry. Clearly, it is one of the best books in this important field of synthetic organic chemistry.

Contenuti

to Cross-Coupling Reactions.- Organoboron Compounds.- Organosilicon Compounds.- Organotin Compounds.- Practical Palladium Catalysts for C-N and C-O Bond Formation.- Direct Arylation via Cleavage of Activated and Unactivated C-H Bonds.

Dettagli dell'edizione

• Editore: Springer Verlag
• Data di pubblicazione: 2002
• Lingua: Inglese
• ISBN 10: 3540421750
• ISBN 13: 9783540421757
• Rilegatura: Copertina rigida
• Numero di pagine: 248
• Redattore: Miyaura Norio
• Contatto del produttore: ProductSafety@springernature.com; ProductSafety@springernature.com; ; Poststr. 9; Darmstadt; 64293; Germania