GPCRs, from Deorphanization to Lead Structure Identification: Ernst Schering Foundation Symposium Proceedings 2006-2 - Rilegato

 
9783540489818: GPCRs, from Deorphanization to Lead Structure Identification: Ernst Schering Foundation Symposium Proceedings 2006-2
Rilegato
ISBN 10: 3540489819 ISBN 13: 9783540489818
Casa editrice: Springer Verlag, 2007

Sinossi

This book offers an insight into the approaches taken by industry and academia to address GPCRs and depict how mature this target class-oriented research has become in the last decade. Coverage also reflects the actual trends in the fast-emerging field of GPCR research in academia and industry. It is based on the international workshop GPCRs: From Deorphanisation to Lead Structure Identification, held in Berlin in May 2006.

Le informazioni nella sezione "Riassunto" possono far riferimento a edizioni diverse di questo titolo.

Contenuti

G-Proteins and GPCRs: From the Beginning.- Modeling GPCRs.- QSAR Modeling of GPCR Ligands: Methodologies and Examples of Applications.- Privileged Structures in GPCRs.- Designing Compound Libraries Targeting GPCRs.- Orphan Seven Transmembrane Receptor Screening.- The Role of GPCR Dimerisation/Oligomerisation in Receptor Signalling.- Deorphanization of G-Protein-Coupled Receptors.- Virus-Encoded G-Protein-Coupled Receptors: Constitutively Active (Dys)Regulators of Cell Function and Their Potential as Drug Target.- Modulation of GPCR Conformationsby Ligands, G-Proteins, and Arrestins.- High Content Screening to Monitor G Protein-Coupled Receptor Internalisation.- High-Throughput Lead Finding and Optimisation for GPCR Targets.

Product Description

Gpcrs, From Deorphanization To Lead Structure Identification: Ernst Schering Foundation Symposium Proceedings 2006-2 by H. Bourne, R. Horuk, J. Kuhnke, 9783540489818, Springer

Le informazioni nella sezione "Su questo libro" possono far riferimento a edizioni diverse di questo titolo.

Editore
Springer Verlag
Data di pubblicazione
2007
Lingua
Inglese
ISBN 10 
3540489819
ISBN 13 
9783540489818
Rilegatura
Copertina rigida
Numero edizione
1
Numero di pagine
267
Redattore
Bourne H., Horuk R., Kuhnke J., Michel H.
Contatto del produttore
non disponibile
Persona responsabile
Springer Nature Customer Service Center GmbH
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Altre edizioni note dello stesso titolo

9783642080319: GPCRs: From Deorphanization to Lead Structure Identification: 2006/2

Edizione in evidenza

ISBN 10:  3642080316 ISBN 13:  9783642080319
Casa editrice: Springer, 2010
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