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Membrane Defenses Against Attack by Complement and Perforins: v.178 - Rilegato

 
9783540546535: Membrane Defenses Against Attack by Complement and Perforins: v.178

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Sinossi

In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.

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Contenuti

List of Contents.- Regulation of Complement by Membrane Proteins: An Overview.- Decay Accelerating Factor (CD55).- Complement Receptor Type 1.- Membrane Cofactor Protein.- Membrane Inhibitor of Reactive Lysis.- Homologous Restriction Factor.- The Effects of Complement Activation on Platelets.- Effects of the Membrane Attack Complex of Complement on Nucleated Cells.- Glycosyl-Phosphatidylinositol Anchoring of Membrane Proteins.- Paroxysmal Nocturnal Hemoglobinuria.- Perforin-Structure, Function, and Regulation.

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Altre edizioni note dello stesso titolo

9783642770166: Membrane Defenses Against Attack by Complement and Perforins: 178

Edizione in evidenza

ISBN 10:  3642770169 ISBN 13:  9783642770166
Casa editrice: Springer-Verlag, 1992
Brossura