In this volume a comprehensive review of membrane proteinsthat regulate complement and perforin-mediated cytolysis ispresented. A detailed analysisis provided of thebiochemical, molecular, and functional features of theseproteins; the glycosyl phosphatidylinositol linkedproteins are covered, with emphasis placed on the functionalimportance of this type of membrane anchor. Further chaptersinclude reviews of the effects of complement activation oncells that are metabolically active, and of the regulationof cell killing by cytotoxic lymphocytes, considering thesimilarities and disparities between the complement andperforin systems. The therapeutic use of recombinant CR1for immune-mediated pathophysiological processes isdiscussed in a separate section.
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List of Contents.- Regulation of Complement by Membrane Proteins: An Overview.- Decay Accelerating Factor (CD55).- Complement Receptor Type 1.- Membrane Cofactor Protein.- Membrane Inhibitor of Reactive Lysis.- Homologous Restriction Factor.- The Effects of Complement Activation on Platelets.- Effects of the Membrane Attack Complex of Complement on Nucleated Cells.- Glycosyl-Phosphatidylinositol Anchoring of Membrane Proteins.- Paroxysmal Nocturnal Hemoglobinuria.- Perforin-Structure, Function, and Regulation.
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. In this volume a comprehensive review of membrane proteinsthat regulate complement and perforin-mediated cytolysis ispresented. A detailed analysisis provided of thebiochemical, molecular, and functional features of theseproteins the glycosyl phos. Codice articolo 5070189
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this volume a comprehensive review of membrane proteinsthat regulate complement and perforin-mediated cytolysis ispresented. A detailed analysisis provided of thebiochemical, molecular, and functional features of theseproteins; the glycosyl phosphatidylinositol linkedproteins are covered, with emphasis placed on the functionalimportance of this type of membrane anchor. Further chaptersinclude reviews of the effects of complement activation oncells that are metabolically active, and of the regulationof cell killing by cytotoxic lymphocytes, considering thesimilarities and disparities between the complement andperforin systems. The therapeutic use of recombinant CR1for immune-mediated pathophysiological processes isdiscussed in a separate section. 204 pp. Englisch. Codice articolo 9783642770166
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - In this volume a comprehensive review of membrane proteinsthat regulate complement and perforin-mediated cytolysis ispresented. A detailed analysisis provided of thebiochemical, molecular, and functional features of theseproteins; the glycosyl phosphatidylinositol linkedproteins are covered, with emphasis placed on the functionalimportance of this type of membrane anchor. Further chaptersinclude reviews of the effects of complement activation oncells that are metabolically active, and of the regulationof cell killing by cytotoxic lymphocytes, considering thesimilarities and disparities between the complement andperforin systems. The therapeutic use of recombinant CR1for immune-mediated pathophysiological processes isdiscussed in a separate section. Codice articolo 9783642770166
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Taschenbuch. Condizione: Neu. Neuware -In this volume a comprehensive review of membrane proteinsthat regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 204 pp. Englisch. Codice articolo 9783642770166
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