Specificity, Function, and Development of NK Cells: NK Cells: The Effector Arm of Innate Immunity: 230 - Brossura
Sinossi
Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.
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Contenuti
A. NK Receptors and Coreceptors.- Regulation of Mouse NK Cells by Structurally Divergent Inhibitory Receptors.- Stimulatory Receptors in NK and T Cells.- Killer Cell Inhibitory Receptor Expression by T Cells.- The CD94/NKG2 C-Type Lectin Receptor Complex.- Triggering of Natural Killer Cell Mediated Cytotoxicity by Costimulatory Molecules.- Fc Receptors on Natural Killer Cells.- Adhesion in NK Cell Function.- B. Activation of NK Cells and Effector Functions.- Signal Transduction During NK Cell Activation: Balancing Opposing Forces.- Effector Pathways of Natural Killer Cells.- C. Development of NK Cells.- Toward a Quantitative Analysis of the Repertoire of Class I MHC-Specific Inhibitory Receptors on Natural Killer Cells.- Ontogeny and Differentiation of Murine Natural Killer Cells and Their Receptors.- D. Role of NK Cells in Infections and Tumors.- Control of Infections by NK Cells.- Natural Killer Cells and Tumor Therapy.
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Specificity, Function, and Development of NK Cells
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors. 264 pp. Englisch. Codice articolo 9783642468612
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Presents recent advances on the function of natural killer cellsOur understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of t. Codice articolo 5061918
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Specificity, Function, and Development of Nk Cells: Nk Cells: the Effector Arm of Innate Immunity (Current Topics in Microbiology and Immunology)
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Taschenbuch. Condizione: Neu. Specificity, Function, and Development of NK Cells | NK Cells: The Effector Arm of Innate Immunity | Klas Kärre (u. a.) | Taschenbuch | ix | Englisch | 2012 | Springer | EAN 9783642468612 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Codice articolo 106368648
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Specificity, Function, and Development of NK Cells
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch. Codice articolo 9783642468612
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Specificity, Function, and Development of NK Cells : NK Cells: The Effector Arm of Innate Immunity
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Springer Berlin Heidelberg, 2012
ISBN 10: 3642468616
ISBN 13: 9783642468612
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Our understanding of the function of natural killer (NK) cells has dramatically changed in recent years. The discovery of NK receptors specific for MHC class I molecules, and the study of the role of co-stimulatory and adhesion molecules have led to an understanding of how NK cells recognize tumor and virally infected cells that have lost expression of MHC class I molecules or have altered distribution of normal cell surface molecules. Such recognition events lead to intracellular signals which can be either stimulatory or inhibitory. This book provides an insight into how NK cells develop, how they learn to distinguish altered cells from normal cells, and into their biological role in controlling infections and tumors. Codice articolo 9783642468612
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