Analytical method development and validation by uv and hplc techniques: UV,HPLC,Dissolution methods - Brossura

Khan, Hajera; Mirza, Shahed; Khan, Faria

 
9783659247972: Analytical method development and validation by uv and hplc techniques: UV,HPLC,Dissolution methods
Brossura
ISBN 10: 3659247979 ISBN 13: 9783659247972
Casa editrice: LAP LAMBERT Academic Publishing, 2012

Sinossi

Gemifloxacin,a flouroquinoline derivative has antibacterial activity. Ambroxol dibromoaminobenzyl derivatives have mucolytic activity.GEM and AMB are available in tablet dosage form (G-cin A,Lupin)for mucolytic action. The present work dealt with simultaneous estimation of GEM and AMB from bulk and tablet formulation by different UV spectrophotometric, RPHPLC and Dissolution techniques. Five UV methods were developed which are accurate, precise, rapid and economical for the estimation of GEM and AMB in Tablet dosage form. The developed HPLC method was validated in terms of accuracy, repeatability, and precision. A good linear relationship was observed for GEM An attempt has been made to carry out the dissolution study of the marketed formulation by applying four established UV-Visible Spectrophotometric methods for estimation of % release of the drug (GEM & AMB).

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Informazioni sull?autore

Hajera Khan has obtained M.Pharmacy in Quality Assurance in 2011.Presently she is working as asst.professor.She is author of several articles published in national and international journals.

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Editore
LAP LAMBERT Academic Publishing
Data di pubblicazione
2012
Lingua
Inglese
ISBN 10 
3659247979
ISBN 13 
9783659247972
Rilegatura
Copertina flessibile
Numero di pagine
124
Contatto del produttore
non disponibile
Persona responsabile
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