Articoli correlati a The Hereditary Basis of Allergic Diseases
The Hereditary Basis of Allergic Diseases - Rilegato
Libro 8 di 50: Progress in Inflammation Research
Sinossi
Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.
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Contenuti
Heredity of allergy and asthma 1.- Genome scans for asthma.- The role of founder populations in mapping complex disease genes: Studies in the South Dakota Hutterites.- Genetic regulation of specific IgE responsiveness.- Genetic variation at the HLA and TCR loci and the development of allergy and asthma.- Chromosome 11q13, FccRI13 and atopic asthma.- Genetic regulation of interleukin-13 production.- The role of interleukin-9 and the interleukin-9 receptor gene candidates in asthma.- Genetics of the nitric oxide synthetic pathway in asthma.- Genetic regulation of leukotriene production and activity.- Genetics of asthma severity.
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The Hereditary Basis of Allergic Diseases
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the gene. Codice articolo 5279391
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Condizione: New. This volume presents scholarly reviews of the emergent and promising genetic factors influencing susceptibility to and progression of allergic diseases such as asthma. It aims to provide a review of current knowledge while also elucidating progress being made in the field. Editor(s): Holgate, Professor Stephen T., MD, DSc, FMedSci; Holloway, John W. Series: Progress in Inflammation Research. Num Pages: 191 pages, biography. BIC Classification: MJCM1; PSAK. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 12. Weight in Grams: 1010. . 2002. Hardback. . . . . Codice articolo V9783764364021
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The Hereditary Basis of Allergic Diseases (Progress in Inflammation Research)
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THE HEREDITARY BASIS OF ALLERGIC DISEASES (PROGRESS IN INFLAMMATION RESEARCH)
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field. Codice articolo 9783764364021
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The Hereditary Basis of Allergic Diseases
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Birkhäuser, Birkhäuser Jul 2002, 2002
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Allergic diseases are complex and involve a range of environmental factors interacting with a susceptible genotype. The familial clustering of diseases, such as asthma and hay fever, has been recognised for over two centuries, but identification of the genetic basis to this had to await the molecular biological revolution. Estimates of the contribution that genetic factors make to asthma susceptibility range from 35% to 70%. For the majority of allergic diseases, segregation analysis has not identified a consistent Mendelian pattern of inheritance, which, when combined with multiple phenotypes and environmental interactions, has made identifying candidate genes especially difficult and, at times, controversial. Part of the difficulty has been lack of agreement over phenotype definitions, reduced power of studies to predict linkage and association, and, importantly, lack of true heterogeneity between populations. Despite these difficulties, the last decade has witnessed enormous progress in this field.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 200 pp. Englisch. Codice articolo 9783764364021
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