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Practical Global Optimization Computing Methods in Molecular Modelling: - for Atomic-resolution Structures of Amyloid Fibrils - Brossura

 
9783846521397: Practical Global Optimization Computing Methods in Molecular Modelling: - for Atomic-resolution Structures of Amyloid Fibrils

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Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etc

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L'autore

Dr Jiapu Zhang (born in 1971) got a Bachelor (1993), two Masters in research (1996, 2000) and a PhD (2005) degrees. During 1996-1998 he lectured in Shandong University, China. Since Feb 2005, he has worked as a Postdocs - Research Scientist - Senior Research Scientist researcher & lecturer/tutor at Melbourne, Ballarat, LaTrobe Universities & CSIRO.

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  • EditoreLAP LAMBERT Academic Publishing
  • Data di pubblicazione2011
  • ISBN 10 3846521396
  • ISBN 13 9783846521397
  • RilegaturaCopertina flessibile
  • LinguaInglese
  • Numero di pagine196
  • Contatto del produttorenon disponibile

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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Zhang JiapuDr Jiapu Zhang (born in 1971) got a Bachelor (1993), two Masters in research (1996, 2000) and a PhD (2005) degrees. During 1996-1998 he lectured in Shandong University, China. Since Feb 2005, he has worked as a Postdocs - . Codice articolo 5496384

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etc 196 pp. Englisch. Codice articolo 9783846521397

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Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etc. Codice articolo 9783846521397

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Taschenbuch. Condizione: Neu. Neuware -Due to the unstable, noncrystalline and insoluble nature of some proteins, the technologies such as X-ray crystallography, NMR (nuclear magnetic resonance) spectroscopy and dual polarization interferometry etc sometimes cannot produce the 3D structures of these proteins. In this condition, molecular modeling (MM) might have been the only strategy to get the 3D structures. The non-covalent interactions such as hydrogen bonding (HB), ionic interactions (SB), Van Der Waals forces (VDW), and hydrophobic packing (HP) are driving the proteins to be able to perform their biological functions. The author has found some SBs play a key role in prion diseases revealed from rabbit prion protein. Neurodegenerative diseases are amyloid fibril diseases. This book studies the HB, VDW, HP interactions for MM of amyloid fibrils in global optimization (GO). The GO MM-algorithms of this book should be very useful in materials science, drug design, IT, operations research, biostatistics and bioinformatics etc research fields. This book was written without advanced mathematical formulas thus it is easily readable for people in wide areas of sciences, engineering, IT, medicine, physiology, education,etcBooks on Demand GmbH, Überseering 33, 22297 Hamburg 196 pp. Englisch. Codice articolo 9783846521397

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Zhang, Jiapu
ISBN 10: 3846521396 ISBN 13: 9783846521397
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Paperback. Condizione: Like New. Like New. book. Codice articolo ERICA79638465213966

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