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Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells.
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Gives new insights into the role of the innate immune system in infection by gram-negative bacteriaPresents a description of endotoxins according to their biosynthesis, genetic constitution, structure, function and mode of interaction with host cellsBrings . Codice articolo 5826324
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Paperback. Condizione: new. Paperback. Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria.Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells. Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens.The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Codice articolo 9789400732674
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Endotoxins: Structure, Function and Recognition
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Springer Netherlands Sep 2012, 2012
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria.Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death.This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases.The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells. 436 pp. Englisch. Codice articolo 9789400732674
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Endotoxins: Structure, Function and Recognition (Subcellular Biochemistry, 53)
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Condizione: New. Endotoxins explores the mechanism behind whole-body inflammation and sepsis by synthesizing the leading research in the field. The biosynthesis, genetic constitution, and structure of endotoxins are presented, in addition to their interaction with host cells. Editor(s): Wang, Xiaoyuan; Quinn, Peter J. Series: Subcellular Biochemistry. Num Pages: 432 pages, biography. BIC Classification: MJCJ; MJCM; MMFM; MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 25. Weight in Grams: 664. . 2012. 2010th Edition. paperback. . . . . Codice articolo V9789400732674
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