Riassunto
Over the last century, medicine has come out of the "black bag" and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiology to material science and nanotechnology. Reflecting the enormous growth and change in biomedical engineering during the infancy of the 21st century, The Biomedical Engineering Handbook enters its third edition as a set of three carefully focused and conveniently organized books.
Reviewing applications at the leading edge of modern biomedical engineering, Tissue Engineering and Artificial Organs explores transport phenomena, biomimetics systems, biotechnology, prostheses, artificial organs, and ethical issues. The book features approximately 90% new material in the tissue engineering section, integrates coverage of life sciences with a new section on molecular biology, and includes a new section on bionanotechnology. Prominent leaders from around the world share their expertise in their respective fields with many new and updated chapters.
New technologies and methods spawned by biomedical engineering have the potential to improve the quality of life for everyone, and Tissue Engineering and Artificial Organs sheds light on the tools that will enable these advances.
Contenuti
MOLECULAR BIOLOGY; Michael Domach
Historical Perspective and Basics of Molecular Biology; Nathan R. Domagalski and Michael Domach
Systems and Technology Involving Bacteria; Nicole Bleckwenn and William Bentley
Recombinant DNA Technology Using Mammalian Cells; Tina Sauerwald and Michael Betenbaugh
TRANSPORT PHENOMENA AND BIOMIMETIC SYSTEMS; Robert J. Fisher
Biomimetic Systems; Robert J. Fisher
Diffusional Processes and Engineering Design; E.N. Lightfoot
Microvascular Heat Transfer; James W. Baish
Perfusion Effects and Hydrodynamics; Robert A. Peattie and Robert J. Fisher
Animal Surrogate Systems; Michael L. Shuler, Sarina G. Harris, and Xinran Li
Arterial Wall Mass Transport: The Possible Role of Blood Phase Resistance in the Localization of Arterial Disease; John M. Tarbell and Yuchen Qui
Control of the Microenvironment; Robert J. Fisher and Robert A. Peattie
Interstitial Transport in the Brain: Principles for Local Drug Delivery; W. Mark Saltzman
BIOTECHNOLOGY; Martin L. Yarmush and Mehmet Toner
Tools for Genome Analysis; Robert Kaiser
Vaccine Production; John G. Aunins, Ann L. Lee, David and B. Volkin
Protein Engineering; Scott Banta
Metabolic Engineering; Scott Banta and Craig Zupke
Monoclonal Antibodies and Their Engineered Fragments; Zaki Megeed, David M. Yarmush, Martin L. Yarmush, and Srikanth Sundaram
Biomolecular Engineering in Oligonucleotide Applications; S. Patrick Walton
Gene Therapy; Cindy Jung and Joseph M. Le Doux
Bio-Nanorobotics: State of the Art and Future Challenges; Ajay Ummat, Gaurav Sharma, C. Mavroidis, and A. Dubey
BIONANOTECHNOLOGY; David E. Reisner
DNA as a Scaffold for Nano-Structure Assembly; Michael Connolly
Directed Evolution of Proteins for Device Applications; Jeremy F. Koscielecki, Jason R. Hillebrecht, and Robert R. Birge
Semiconductor Quantum Dots for Molecular and Cellular Imaging; Andrew Michael Smith and Shuming Nie
Bionanotechnology for Bioanalysis; Lin Wang and Weihong Tan
Nano-Hydroxyapatite for Biomedical Applications; Zongtao Zhang, Yunzhi Yang, and Joo L. Ong
Nanotechnology Provides New Tools for Biomedical Optics; Jennifer L. West, Rebekah A. Drezek, and Naomi J. Halas
Nanomaterials Perspectives and Possibilities in Nanomedicine; Kimberly L. Douglas, Shawn D. Carrigan, and Maryam Tabrizian
Biomedical Nanoengineering for Nanomedicine; Jie Han
Physiogenomics: Integrating Systems Engineering and Nanotechnology for Personalized Medicine; Gualberto Ruaño, Andreas Windemuth, and Theodore R. Holford
Bionanotechnology Patenting: Challenges and Opportunities; Raj Bawa, S.R. Bawa, Stephen B. Maebius, and Chid Iyer
TISSUE ENGINEERING; John P. Fisher and Antonios G. Mikos
Fundamentals of Stem Cell Tissue Engineering; Arnold I. Caplan
Growth Factors and Morphogens: Signals for Tissue Engineering; A. Hari Reddi
Extracellular Matrix: Structure, Function, and Applications to Tissue Engineering; Mary C. Farach-Carson, Roger C. Wagner, and Kristi L. Kiick
Mechanical Forces on Cells; Yan-Ting Shiu
Cell Adhesion; Aaron S. Goldstein
Cell Migration; Gang Cheng and Kyriacos Zygourakis
Inflammatory and Immune Responses to Tissue Engineered Devices; James M. Anderson
Polymeric Scaffolds for Tissue Engineering Applications; Diana M. Yoon and John P. Fisher
Calcium Phosphate Ceramics for Bone Tissue Engineering; P. Quinten Ruhé, Joop G.C. Wolke, Paul H.M. Spauwen, and John A. Jansen
Biomimetic Materials; Andrés J. García
Nanocomposite Scaffolds for Tissue Engineering; Amit S. Mistry, Xinfeng Shi, and Antonios G. Mikos
Roles of Thermodynamic State and Molecular Mobility in Biopreservation; Alptekin Aksan and Mehmet Toner
Drug Delivery; C. Becker and A. Göpferich
Gene Therapy; J.M. Munson and W.T. Godbey
Tissue Engineering Bioreactors; Jose F. Alvarez-Barreto and Vassilios I. Sikavitsas
Animal Models for Evaluation of Tissue-Engineered Orthopedic Implants; Lichun Lu, Esmaiel Jabbari, Michael J. Moore, and Michael J. Yaszemski
The Regulation of Engineered Tissues: Emerging Approaches; Kiki B. Hellman and David Smith
Bioengineering of Human Skin Substitutes; Dorothy M. Supp and Steven T. Boyce
Nerve Regeneration: Tissue Engineering Strategies; Jennifer B. Recknor and Surya K. Mallapragada
Gene Therapy and Tissue Engineering Based on Muscle-Derived Stem Cells: Potential for Musculoskeletal Tissue Regeneration and Repair; Johnny Huard, Baohong Cao, Yong Li, and Hairong Peng
Tissue Engineering Applications - Bone; Ayse B. Celil, Scott Guelcher, Jeffrey O. Hollinger, and Michael Miller
Cartilage Tissue Engineering; Fan Yang and Jennifer H. Elisseeff
Tissue Engineering of the Temporomandibular Joint; Mark E.K. Wong, Kyle D. Allen, and Kyriacos A. Athanasiou
Engineering Smooth Muscle; Yu Ching Yung and David J. Mooney
Esophagus: A Tissue Engineering Challenge; B.D. Ratner, B.L. Beckstead, K.S. Chian, and A.C. Ritchie
Tissue Engineered Vascular Grafts; Rachael H. Schmedlen, Wafa M. Elbjeirami, Andrea S. Gobin, and Jennifer L. West
Cardiac Tissue Engineering: Matching Native Architecture and Function to Develop Safe and Efficient Therapy; Nenad Bursac
Tissue Engineering of Heart Valves; K. Jane Grande-Allen
Tissue Engineering: Use of Stem Cells and Cloning in the Regeneration of Urologic Organs; J. Daniell Rackley and Anthony Atala
Hepatic Tissue Engineering for Adjunct and Temporary Liver Support; François Berthiaume, Arno W. Tilles, Mehmet Toner, Martin L. Yarmush, and Christina Chan
Tissue Engineering of Renal Replacement Therapy; William H. Fissell and H. David Humes
The Bioengineering of Dental Tissues; Rena N. D'Souza and Songtao Shi
Tracheal Tissue Engineering; Brian Dunham, Paul Flint, Sunil Singhal, Catherine Le Visage, and Kam Leong
PROSTHESES AND ARTIFICIAL ORGANS; Pierre M. Galletti and Robert M. Nerem
Artificial Heart and Circulatory Assist Devices; Gerson Rosenberg
Cardiac Valve Prostheses; Gerson Rosenberg
Vascular Grafts; David N. Ku and Robert C. Allen
Artificial Lungs and Blood-Gas Exchange Devices; Pierre M. Galletti and K. Clark
Artificial Kidney; C. Mavroidis
Peritoneal Dialysis Equipment; Michael J. Lysaght and John Moran
Therapeutic Apheresis and Blood Fractionation; Andrew L. Zydney
Liver Support Systems; Pierre M. Galletti and Hugo O. Jauregui
Artificial Pancreas; Pierre M. Galletti, Clark K. Colton, Michel Jaffrin, and Genard Reach
Nerve Guidance Channels; Robert F. Valentini
Tracheal, Laryngeal, and Esophageal Replacement Devices; Tatsuo Nakamura and Yasuhiko Shimizu
Artificial Blood; Marcos Intaglietta and Robert M. Winslow
Artificial Skin and Dermal Equivalents; Ioaniss V. Yannas
ETHICS; David E. Reisner
Beneficence, Nonmaleficence, and Medical Technology; Joseph D. Bronzino
Ethical Issues Related to Clinical Research; Joseph D. Bronzino
INDEX
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