Tissue Microarrays

Lingua: inglese

Editore: Humana Aug 2010, 2010

1607618052 / 9781607618058

Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000

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This item is printed on demand - Print on Demand Titel. Neuware -The tissue microarray (TMA) method presents as a modern high technology, although its roots go back to the 80s when researchers frst started to combine several small pieces of tissues into so-called sausage blocks. In this respect, the TMA invention was not frstly characterized by technical improvements, but its true novelty was to link clinical data to the tissues that were combined on one slide. The very high number of tissues that can be included into one TMA, the small size and regular shape of the tissue spots, the preser- tion of integrity of the donor tissue blocks, and the highly organized array pattern that allows for reliable allocation of clinical data to individual tissue spots made it a discrete technique with unique features. When the TMA technology was developed 12 years ago, its beneft was controversially debated. While many researchers welcomed the method enthusiastically, there were c- cerns by others that results obtained from the small tissue cores used for TMA making would not be suffciently representative of the donor tissues. Meanwhile, the increasing use of this technology has imposingly demonstrated its tremendous utility in research. In fact, basically all clinically relevant associations between molecular markers and clinical endpoints could be reproduced using only one single 0. 6 mm core per tissue sample so that TMAs have nowadays become a standard tool allowing for a new dimension of tissue analysis.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 204 pp. Englisch.…

Codice articolo 9781607618058

Titolo
Tissue Microarrays
Autore
Ronald Simon
Editore
Humana Aug 2010
Anno di pubblicazione
2010
Condizione
Neu
Rilegatura
Buch
Lingua
inglese
ISBN 10
1607618052
ISBN 13
9781607618058
Peso dell'articolo
637 grammi
Dimensioni
260x183x18 mm

buchversandmimpf2000

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