Alamelu m (26 risultati)

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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 124 pp. Englisch.

Buch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Fibrinolysis, the process of breaking down the fibrin network, was reported in 1925 by Fischer, who demonstrated that explants of virally induced chicken tumors rapidly caused lysis of plasma clots, whereas explants of normal tissue did not. This observation provided evidence for the importance of fibrinolysis in cancer. Then, in 1933, Tillett and Garner observed the liquefaction of a fibrin clot by the plasma of many patients who had recovered from acute hemolytic streptococcal infections. These investigators showed that broth cultures of hemolytic streptococci derived from patients could rapidly liquefy normal human fibrin clots. This suggested that fibrinolysis might play a key role in homeostasis, although its regulation mechanism was unknown. Fibrinolysis is now known to be regulated by four components, namely the plasminogen activators that function to convert plasminogen into plasmin to initiate fibrin degradation, such as tissue-type and urokinase-type plasminogen activators, the plasminogen activator inhibitors that block the plasminogen activators, the plasmin inhibitors such as alpha2-antiplasmin, and finally the enzymes that block plasminogen binding sites on fibrin or the endothelial cell surface, such as the thrombin activatable fibrinolysis inhibitor. Originally, fibrinolysis was thought to be only responsible for promoting vascular patency, the failure of which resulted in myocardial infarction and stroke. However, recent studies from multiple laboratories have identified the key role of fibrinolysis in a host of physiological and pathophysiological processes. Most recently, fibrinolysis has been suggested to play a role in forming the premetastatic niche, a hospitable site for future metastases in distal tissues, which is formed by secretions from the primary tumor before the departure of metastatic cancer cells. This book explores the multifaceted and intriguing role of fibrinolysis in several processes, including cancer, cardiovascular disease, neuroinflammation, and infection. The latest advances in fibrinolytic therapies are also discussed, which illustrates the complexity and depth of the field.…

Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Fibrinolysis, the process of breaking down the fibrin network, was reported in 1925 by Fischer, who demonstrated that explants of virally induced chicken tumors rapidly caused lysis of plasma clots, whereas explants of normal tissue did not. This observation provided evidence for the importance of fibrinolysis in cancer. Then, in 1933, Tillett and Garner observed the liquefaction of a fibrin clot by the plasma of many patients who had recovered from acute hemolytic streptococcal infections. These investigators showed that broth cultures of hemolytic streptococci derived from patients could rapidly liquefy normal human fibrin clots. This suggested that fibrinolysis might play a key role in homeostasis, although its regulation mechanism was unknown. Fibrinolysis is now known to be regulated by four components, namely the plasminogen activators that function to convert plasminogen into plasmin to initiate fibrin degradation, such as tissue-type and urokinase-type plasminogen activators, the plasminogen activator inhibitors that block the plasminogen activators, the plasmin inhibitors such as alpha2-antiplasmin, and finally the enzymes that block plasminogen binding sites on fibrin or the endothelial cell surface, such as the thrombin activatable fibrinolysis inhibitor. Originally, fibrinolysis was thought to be only responsible for promoting vascular patency, the failure of which resulted in myocardial infarction and stroke. However, recent studies from multiple laboratories have identified the key role of fibrinolysis in a host of physiological and pathophysiological processes. Most recently, fibrinolysis has been suggested to play a role in forming the premetastatic niche, a hospitable site for future metastases in distal tissues, which is formed by secretions from the primary tumor before the departure of metastatic cancer cells. This book explores the multifaceted and intriguing role of fibrinolysis in several processes, including cancer, cardiovascular disease, neuroinflammation, and infection. The latest advances in fibrinolytic therapies are also discussed, which illustrates the complexity and depth of the field.Books on Demand GmbH, Überseering 33, 22297 Hamburg 124 pp. Englisch.…

Buch. Condizione: Neu. Fibrinolysis | Past, Present and Future | Buch | Englisch | 2025 | IntechOpen | EAN 9780850144680 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand.

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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. KlappentextIn the event of a disastrous event leading to the loss of communication networks, ad-hoc networks are a potent wireless communication resource because of their unique features including being quickly deployable and having a di.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Fast moving ad-hoc networks are the future technology that can solve many issues the world is needing now like E Commerce delivery through drones, agriculture, vaccine delivery, human rescue system, and more. Flying ad-hoc networks (FANETs), vehicular ad-ho.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In the event of a disastrous event leading to the loss of communication networks, ad-hoc networks are a potent wireless communication resource because of their unique features including being quickly deployable and having a distributed nature, large coverage area, reduced cost, and more. Flying ad-hoc networks (FANETS) and vehicular ad-hoc networks (VANETS) are the future technology and can solve many problems in e-commerce delivery through drones, agriculture, vaccine delivery, and more. The unique characteristics of these networks and special requirements have created new challenges for the research community in recent decades. Modelling and Simulation of Fast-Moving Ad-Hoc Networks (FANETs and VANETs) enhances the modelling and simulation aspects of FANETS and VANETS and understands the protocols in mac layer and network layers for fast-moving ad-hoc networks. It presents simulations run using various simulation tools and measures the performance metrics of ad-hoc networks. Covering topics such as emulation tools, secure communication, and modelling software, this premier reference source is an excellent resource for computer scientists, IT specialists, business leaders and managers, supply chain and logistics management, libraries, students, government officials, international organizations, law enforcement, engineers, agriculturalists, researchers, and academicians.…