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Paperback. Condizione: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.
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Hardback. Condizione: Very Good. xvii + 428 pp. Rubber-stamped on front free endpaper. book.
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Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 448 | Sprache: Englisch | Produktart: Bücher | Prostate cancer is the most common noncutaneous prostate cancer. Research has revealed several distinct malignancy and the second leading cause of cancer mechanisms of castration-resistant disease that may deaths among men in the Uni…ted States. It is a critical converge in patients with disease progression on public health problem and remains incurable in the ADT. Many approaches are currently being evaluated metastatic setting with mortality that usually occurs as to improve the treatment of this condition and these a result of castration-resistant disease. fndings have identifed several potential targets for Since Huggins and Hodges¿ report of the dra- therapeutic intervention. These include drugs that are matic clinical effects of suppressing serum testos- more active or less toxic chemotherapy agents; drugs terone levels in men with advanced prostate cancer that induce androgen deprivation; drugs that target in 1941, hormone therapy (also called androgen the androgen receptor and/or androgen synthesis; deprivation therapy [ADT]) has become widely drugs that target specifc pathways, including ang- accepted as the mainstay of therapy for the treat- genesis and tyrosine kinase inhibitors, endothelin ment of advanced prostate cancer. ADT combined antagonists and matrix metalloproteinase inhibitors; with radiation therapy is a standard of care in the and immunologic approaches. Many of these agents treatment of men with locally advanced prostate seem promising and the rationale and effcacy of cancer on the basis of evidence that shows improved these emerging therapies remain to be validated in survival. The role of ADT in the management of future clinical trials.
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Condizione: New. pp. 848 Index.
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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics (Cancer Drug Discovery and Development)
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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics (Cancer Drug Discovery and Development)
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Taschenbuch. Condizione: Neu. Handbook of Anticancer Pharmacokinetics and Pharmacodynamics | Michelle A. Rudek (u. a.) | Taschenbuch | Cancer Drug Discovery and Development | ix | Englisch | 2016 | Springer | EAN 9781493938988 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen…[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics (Cancer Drug Discovery and Development)
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Condizione: New. This book offers a detailed, step-by-step guide to the successful design and approval of anticancer drugs. It covers all steps, from the identification of cancer-specific molecular targets to clinical trial design and all the phases of clinical trials. Editor(s): Rudek, Michelle A.; Chau, Cindy H.; Figg, William… D.; McLeod, Howard L. Series: Cancer Drug Discovery and Development. Num Pages: 845 pages, 99 black & white illustrations, 46 colour illustrations. BIC Classification: MQP. Category: (P) Professional & Vocational. Dimension: 185 x 258 x 37. Weight in Grams: 1620. . 2014. Second Edition 2014. hardcover. . . . .
Lingua: Inglese
Editore: Springer New York, Springer New York, 2014
Serie: Libro 80 di 96 - Cancer Drug Discovery and Development
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacody…namics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer.Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs.Road map to anticancer drug development from discovery to NDA submissionDiscussion of molecular targets and preclinical screeningDevelopment and validation of bioanalytical methodsChapters on clinical trial design and phase 0, I, II, III clinical trialsPharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agentsReview of the drug development process from both laboratory and clinical perspectivesNew technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development.
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Condizione: New. Brand New! Fast Delivery This is an International Edition and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 6-10 days and we do have flat rate for up to 2LB. Extra shipping charges will be requested if t…he Book weight is more than 5 LB. This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.
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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics (Cancer Drug Discovery and Development)
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Serie: Libro 80 di 96 - Cancer Drug Discovery and Development
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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics (Cancer Drug Discovery and Development)
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Condizione: New. This book offers a detailed, step-by-step guide to the successful design and approval of anticancer drugs. It covers all steps, from the identification of cancer-specific molecular targets to clinical trial design and all the phases of clinical trials. Editor(s): Rudek, Michelle A.; Chau, Cindy H.; Figg, William… D.; McLeod, Howard L. Series: Cancer Drug Discovery and Development. Num Pages: 845 pages, 99 black & white illustrations, 46 colour illustrations. BIC Classification: MQP. Category: (P) Professional & Vocational. Dimension: 185 x 258 x 37. Weight in Grams: 1620. . 2014. Second Edition 2014. hardcover. . . . . Books ship from the US and Ireland.
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
Rudek, M. A. (Editor)/ Chau, C. H. (Editor)/ Figg, W. D. (Editor)/ Mcleod, H. L. (Editor)
Lingua: Inglese
Editore: Springer Verlag, 2014
Serie: Libro 80 di 96 - Cancer Drug Discovery and Development
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a comprehensive guide to the spectrum of emerging pharmacologic agentsCovers both standard of care and investigational therapeuticsWritten by recognized international authorities in the fieldWell suited .
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Prostate cancer is the most common noncutaneous prostate cancer. Research has revealed several distinct malignancy and the second leading cause of cancer mechanisms of castration-resistant disease that may deaths among men in the United S…tates. It is a critical converge in patients with disease progression on public health problem and remains incurable in the ADT. Many approaches are currently being evaluated metastatic setting with mortality that usually occurs as to improve the treatment of this condition and these a result of castration-resistant disease. fndings have identifed several potential targets for Since Huggins and Hodges' report of the dra- therapeutic intervention. These include drugs that are matic clinical effects of suppressing serum testos- more active or less toxic chemotherapy agents; drugs terone levels in men with advanced prostate cancer that induce androgen deprivation; drugs that target in 1941, hormone therapy (also called androgen the androgen receptor and/or androgen synthesis; deprivation therapy [ADT]) has become widely drugs that target specifc pathways, including ang- accepted as the mainstay of therapy for the treat- genesis and tyrosine kinase inhibitors, endothelin ment of advanced prostate cancer. ADT combined antagonists and matrix metalloproteinase inhibitors; with radiation therapy is a standard of care in the and immunologic approaches. Many of these agents treatment of men with locally advanced prostate seem promising and the rationale and effcacy of cancer on the basis of evidence that shows improved these emerging therapies remain to be validated in survival. The role of ADT in the management of future clinical trials. 448 pp. Englisch.
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
Rudek, Michelle A.|Chau, Cindy H.|Figg, William D.|McLeod, Howard L.
Lingua: Inglese
Editore: Springer New York, 2014
Serie: Libro 80 di 96 - Cancer Drug Discovery and Development
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Gebunden. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a detailed step-by-step guide to the successful design and approval of anticancer drugsFeatures updated research from 1st Edition and new, additional chaptersExplores a wide variety of issues, incl…uding clinical trial design, precl.
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Buch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Prostate cancer is the most common noncutaneous prostate cancer. Research has revealed several distinct malignancy and the second leading cause of cancer mechanisms of castration-resistant disease that may deaths among men in the United State…s. It is a critical converge in patients with disease progression on public health problem and remains incurable in the ADT. Many approaches are currently being evaluated metastatic setting with mortality that usually occurs as to improve the treatment of this condition and these a result of castration-resistant disease. fndings have identifed several potential targets for Since Huggins and Hodges¿ report of the dra- therapeutic intervention. These include drugs that are matic clinical effects of suppressing serum testos- more active or less toxic chemotherapy agents; drugs terone levels in men with advanced prostate cancer that induce androgen deprivation; drugs that target in 1941, hormone therapy (also called androgen the androgen receptor and/or androgen synthesis; deprivation therapy [ADT]) has become widely drugs that target specifc pathways, including ang- accepted as the mainstay of therapy for the treat- genesis and tyrosine kinase inhibitors, endothelin ment of advanced prostate cancer. ADT combined antagonists and matrix metalloproteinase inhibitors; with radiation therapy is a standard of care in the and immunologic approaches. Many of these agents treatment of men with locally advanced prostate seem promising and the rationale and effcacy of cancer on the basis of evidence that shows improved these emerging therapies remain to be validated in survival. The role of ADT in the management of future clinical trials.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 448 pp. Englisch.
Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
Rudek, Michelle A.|Chau, Cindy H.|Figg, William D.|McLeod, Howard L.
Lingua: Inglese
Editore: Springer New York, 2016
Serie: Libro 80 di 96 - Cancer Drug Discovery and Development
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a detailed step-by-step guide to the successful design and approval of anticancer drugsFeatures updated research from 1st Edition and new, additional chaptersExplores a wide variety of issues, including clin…ical trial design, precl.
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Buch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Prostate cancer is the most common noncutaneous prostate cancer. Research has revealed several distinct malignancy and the second leading cause of cancer mechanisms of castration-resistant disease that may deaths among men in the United States…. It is a critical converge in patients with disease progression on public health problem and remains incurable in the ADT. Many approaches are currently being evaluated metastatic setting with mortality that usually occurs as to improve the treatment of this condition and these a result of castration-resistant disease. fndings have identifed several potential targets for Since Huggins and Hodges' report of the dra- therapeutic intervention. These include drugs that are matic clinical effects of suppressing serum testos- more active or less toxic chemotherapy agents; drugs terone levels in men with advanced prostate cancer that induce androgen deprivation; drugs that target in 1941, hormone therapy (also called androgen the androgen receptor and/or androgen synthesis; deprivation therapy [ADT]) has become widely drugs that target specifc pathways, including ang- accepted as the mainstay of therapy for the treat- genesis and tyrosine kinase inhibitors, endothelin ment of advanced prostate cancer. ADT combined antagonists and matrix metalloproteinase inhibitors; with radiation therapy is a standard of care in the and immunologic approaches. Many of these agents treatment of men with locally advanced prostate seem promising and the rationale and effcacy of cancer on the basis of evidence that shows improved these emerging therapies remain to be validated in survival. The role of ADT in the management of future clinical trials.
Lingua: Inglese
Editore: Springer New York Jan 2014, 2014
Serie: Libro 80 di 96 - Cancer Drug Discovery and Development
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Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetic…s and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer.Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs.Road map to anticancer drug development from discovery to NDA submissionDiscussion of molecular targets and preclinical screeningDevelopment and validation of bioanalytical methodsChapters on clinical trial design and phase 0, I, II, III clinical trialsPharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agentsReview of the drug development process from both laboratory and clinical perspectivesNew technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development 848 pp. Englisch.
