daniel bar shalom (18 risultati)

Condizione: New. In.

Condizione: New. In.

Condizione: New.

Condizione: New.

Taschenbuch. Condizione: Neu. Pediatric Formulations | A Roadmap | Daniel Bar-Shalom (u. a.) | Taschenbuch | AAPS Advances in the Pharmaceutical Sciences Series | xv | Englisch | 2016 | Springer | EAN 9781493945214 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Condizione: New.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.

Condizione: New. pp. xv + 439.

Paperback. Condizione: Brand New. reprint edition. 454 pages. 9.25x6.10x1.08 inches. In Stock.

Buch. Condizione: Neu. Neuware - Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.

Hardcover. Condizione: Good. Micha Bar-Am [Chief Photographer], Daniel Shalom ( (illustratore). Presumed First Edition, First printing. 240 pages. Text is in Hebrew and English. Illustrations (some in color). Maps. Illustrated endpapers. Printed by Peli Printing Works Ltd., Givatayim. Cover has some wear and soiling and bumped corners. Ink inscription in Hebrew on half-title page which reads "To Avigdor, Upon your entering the large Air Force family Good luckPeleg Tamir December 1971". Peleg Tamir was a senior officer in the IDF air force ( and also was in the Irgun before the establishment of the State). This book details the Air Force of Israel from it's beginning to about 1971. The Ministry of Defense oversees most of the Israeli security forces, including the Israel Defense Forces (IDF), Israel Military Industries (IMI), and Israel Aerospace Industries (IAI). The MOD was established when the British Mandate of Palestine ended, and the British Army departed Palestine and the State of Israel was formed. This ended the rag-tag militia units during British rule and gave way to the formal defense of the Jewish state. The Israeli Air Force (IAF) operates as the aerial warfare branch of the Israel Defense Forces. It was founded on May 28, 1948, shortly after the Israeli Declaration of Independence. The Israeli Air Force was established using commandeered or donated civilian aircraft and obsolete and surplus World War II combat aircraft. Eventually, more aircraft were procured, including Boeing B-17s, Bristol Beaufighters, de Havilland Mosquitoes and P-51D Mustangs. The Israeli Air Force played an important part in Operation Kadesh, Israel's part in the 1956 Suez Crisis, dropping paratroopers at the Mitla Pass. On June 5, 1967, the first day of the Six-Day War, the Israeli Air Force performed Operation Focus, debilitating the opposing Arab air forces and attaining air supremacy for the remainder of the war. Shortly after the end of the Six-Day War, Egypt initiated the War of Attrition, and the Israeli Air Force performed repeated bombings of strategic targets deep within enemy territory. When the Yom Kippur War broke out on October 6, 1973, the close air support it provided allowed Israeli troops on the ground to stem the tide and eventually go on the offensive.

Condizione: new. Questo è un articolo print on demand.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed. 456 pp. Englisch.

Condizione: New. Print on Demand.

Condizione: New. PRINT ON DEMAND.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 456 pp. Englisch.

Condizione: New. Print on Demand pp. xv + 439 76 Illus. (36 Col.).

Condizione: New. PRINT ON DEMAND pp. xv + 439.