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Antimutagenesis and Anticarcinogenesis Mechanisms (Basic Life Sciences)
Delbert M. Shankel; Philip E. Hartman; Tsuneo Kada; Alexander Hollaender; Claire M. Wilson; Gregory Kuny
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Hardcover. 605pp. Some shelf wear, else VG without dj.
Editore: University of Kansas, 1983
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Aggiungi al carrello144pp. Slightly soiled cover, else near new, fresh unused condition, text clean & binding tight.
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Antimutagenesis Studies in Japan.- Cancer Prevention: Underlying Principles and Practical Proposals.- Antimutagens in Food.- Anticlastogenic Dietary Factors Assessed in Mammalian Assays.- Antigenotoxic Activity of Carotenoids in Carcinogen-Exposed… Populations.- Plant Antimutagens.- Antimutagens and Anticarcinogens in Environmental Toxicology.- Human Biomonitoring in Exposure to Environmental Genotoxicants.- The Concept of Activity Profiles of Antimutagens.- Prevention of Formation of Important Mutagens/Carcinogens in the Human Food Chain.- Free Radicals.- Free Radical Reactions with DNA and its Nucleotides.- Mechanisms of Inactivation of Oxygen Radicals by Dietary Antioxidants and their Models.- Role of Dietary Antioxidants in Protection Against Oxidative Damage.- Antitumor Initiators And Carcinogenesis.- Inhibition of Carcinogenesis by Naturally-occurring and Synthetic Compounds.- Newly Recognized Anticarcinogenic Fatty Acids.- Caloric Restriction in Experimental Carcinogenesis.- Carcinogenicity and Modification of Carcinogenic Response by Antioxidants.- Antitumor Promoters and Carcinogenesis.- Inhibition of Tumor Promotion by DL- -Difluoromethyl-Ornithine, A Specific Irreversible Inhibitor of Ornithine Decarboxylase.- New Antitumor Promoters: (-)-Epigallocatechin Gallate and Sarcophytols A and B.- Chemoprevention of Mammary Cancer by Retinoids.- Aspects Of Mammalian And Human Genetics.- Suppression of Tumor Promotion by Inhibitors of Poly(ADP)ribose Formation.- Antimutagenic Activity of Vitamins in Cultured Mammalian Cells.- Microcell-Mediated Chromosome Transfer: A Strategy for Studying the Genetics and Molecular Pathology of Human Hereditary Diseases with Abnormal Responses to DNA Damage.- Molecular Aspects Of Mutagenesis And Antimutagenesis.- Genetic Analyses of Cellular Functions Required for UV Mutagenesis in Escherichia coli.- Position of a Single Acetylaminofluorene Adduct within a Mutational Hot Spot is Critical for the Related Mutagenic Event.- Fidelity of Animal Cell DNA Polymerases and and of a Human DNA Replication Complex.- Molecular Mechanisms of Replicational Fidelity in Escherichia Coli.- Oncogenes And Antioncogenes.- Permanent Conversion of NIH3T3 Cells Transformed by Activated c-Ha-ras, c-Ki-ras, N-ras, OR c-raf, and of Human Pancreatic Adenocarcinoma Containing Activated c-Ki-ras to Apparently Normal Cells by Treatment with the Antibiotic Azatyrosine.- Oncogenes of Stomach Cancers.- Oncogenic Potential and Normal Function of the Proto-oncogenes Encoding Protein-Tyrosine Kinases.- Short Papers.- Inhibition of the Genotoxicity of 3-Amino-1-Methyl-5H- Pyrido[4,3-b]Indole (Trp-P-2) in Drosophila by Chlorophyll.- Inhibition of Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK)-Induced Lung Tumors and DNA Methylation in F344 Rats and A/J Mice by Phenethyl Isothiocyanate.- Proteolytic Activation of UmuD and MucA Proteins for SOS Mutagenesis.- Analysis of Bleomycin-resistant DNA Synthesis in Cells from an Inherited Human Disorder, Ataxia Telangiectasia.- Tumor Dose-response Studies with Aflatoxin B1 and the Ambivalent Modulator Indole-3-carbinol: Inhibitory versus Promotional Potency.- Antimutagenesis in Yeast by Sodium Chloride, Potassium Chloride, and Sodium Saccharin.- The Use of Drosophila as an in VIVO System to Study Modifiers of Chemical Mutagenesis.- The Mouse Mutant, ¿Wasted¿: Tissue-specific Radiation Sensitivity and Hematopoietic Cell Lineages.- Antimutagenic Effects of Tumor Promoters¿Co-mutagenic Effects of Co-carcinogens.- Antimutagenic Effects of Dimethyl Sulfoxide on Metabolism and Genotoxicity of Benzene in Vivo.- Possible Antitumor Promoter in the Glandular Stomach: Calcium Chloride.- Reversion of Transformed NIH 3T3 Cells to Flat Cells by Inhibitors of Poly(ADP-ribose) Polymerase.- Inactivation of Mutagenic Heterocyclic and Aryl Amines by Linoleic Acid 13-Monohydroperoxide and Methemoglobin.- Establishment of a Highly Reproducible Transformation Assay of a Ras-Transfected Balb 3T3 Clone by Treatment with Promoters.- Antimutagenic Effect of umuD Mutant Plasmids: Isolation and Characterization of umuD Mutants reduced in their Ability to Promote UV Mutagenesis in Escherichia Coli.- Antitumor-promoting Activity of Sesquiterpene Isolated from an Herbal Spice.- Inhibitory Effects of Chlorogenic Acid, Reserpine, Polyprenoic ACID (E-5166), or Coffee on Hepatocarcinogenesis in Rats and Hamsters.- Antimutagenic Structure Modification of Quinoline: Fluorine-substitution at Position-3.- Mutagenicity and Antimutagenicity of Thai Medicinal Plants.- Influence of Potential Antioxidants on Free-radical Damage of Lymphocytes.- Specificity of Antimutagens Against Chemical Mutagens in Microbial Systems.- Classification of Mechanisms of Inhibitors of Mutagenesis and Carcinogenesis.- Antimutagenic Effects of Chlorophyllin.- Participants, Speakers, and Chairmen.
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). One important elem…ent of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk area, and vice versa (25,42). Populations that customarily consume fruits and vegetables and also whole grain cereal products generally have a lower risk of cardiovascular diseases and specific types of cancer than populations with a lower intake of such foods, everything else being equal (63). In the last few years, research has provided mechanistic explanations as to the reasons for the protective effects of specific foods. This paper will emphasize the mechanisms whereby cancer risks are reduced by dietary modification.
Antimutagenesis and Anticarcinogenesis Mechanisms (Basic Life Sciences)
Shankel, Delbert M.; Hartman, Philip E.; Kada, Tsuneo; Hollaender, Alexander; Wilson, Claire M.; Kuny, Gregory
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Antimutagenesis and Anticarcinogenesis Mechanisms III. Basic Life Sciences. Volume 61.
BRONZETTI, Giorgio, HAYATSU, Hikoya, DE FLORA, Silvio, WATERS, Michael D., & SHANKEL, Delbert M. ed.
Editore: Plenum Press, 1993., 1993
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Aggiungi al carrelloHardcover. Some wear to top corners, small scratch to RH edge of front cover, contents very good condition. No dj. Papers from the Third International Conference on Mechanisms of Antimutagenesis & Anticarcinogenesis. Includes essays under the topics of Inhibition of Mutagenesis & Carcinogens by Extracellular Mechanisms, Modulati…on of Metabolism & Blocking of Reactive Species, Modulation of DNA Repair & Control of Gene Expression, Mechanisms of Inhibition of Tumor Promotion, Progression, Invasion, & Metastases, & Prospects in Chemoprevention of Mutation & Cancer. xi, 494pp. 11436.
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Antimutagenesis and Anticarcinogenesis Mechanisms
Delbert M. Shankel|Philip E. Hartman|Tsuneo Kada|Alexander Hollaender|Claire M. Wilson|Gregory Kuny
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Condizione: New. pp. 622.
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Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 493 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
Antimutagenesis and Anticarcinogenesis Mechanisms III
Bronzetti, Giorgio|Hayatsu, Hikoya|De Flora, Silvio|Waters, Michael D.|Shankel, Delbert M.
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Gebunden. Condizione: New. Mechanistic Approaches to Antimutagenesis and Anticarcinogenesis: Multiple Mechanisms L.M. De Luca. Inhibition of Mutagenesis and Carcinogenesis by Extracellular Mechanisms: Inhibition of Nitrosation H. Bartsch, et al. Modulation of Metabolism and Blockin.
Antimutagenesis and Anticarcinogenesis Mechanisms III
Bronzetti, Giorgio/ Hayatsu, Hikoya/ De Flora, Silvio (Contributor)
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Delbert M. Shankel Departments of }1icrobiology and Biochemistry The University of Kansas Lawrence, Kansas 66045 Welcome to the 'International Conference on Mecha. nisms of Antimutagen esis and Anticarcinogenesis. ' We are delighted that so many o…f you have chosen to attend this first meeting on this important topic. The significance of genetic changes in cells has been recognized for many years. The seminal observations of Henri in 1914 (UV), Muller in 1927 (X-rays), and Auerbach in 1946 (chemical agents) established the fact that physical and chemical agents which may be present in our environment are capable of producing profound changes in heredity. It is now well-estab lished, of course, that such changes can result in the development of can cer, produce hereditary birth defects, alter microorganisms to cause drug resistance, or other harmful (or even beneficial) changes; it is likely that the processes of mutagenesis and the intricate balance between muta genesis and antimutagenesis are involved in aging, evolution, and other fundamental life processe8. Consequently, we hope and believe that assem bling thi. s group of scientists to share current fundamental and applied research in these areas will lead to a better understanding of these proc esses and to long-term benefits for society. As stated clearly by Garfield (4), 'Almost every aspect of modern liv ing exposes us to health risks.
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Buch. Condizione: Neu. Neuware - Mechanistic Approaches to Antimutagenesis and Anticarcinogenesis: Multiple Mechanisms; L.M. De Luca. Inhibition of Mutagenesis and Carcinogenesis by Extracellular Mechanisms: Inhibition of Nitrosation; H. Bartsch, et al. Modulation of Metabolism and Blocking of Reactive Species: Organ-Specific Mo…dification of Carcinogenesis by Antitoxidants in Rats; M. Hirose, et al. Modulation of DNA Repair and Control of Gene Expression: Molecular Control of Human Papillomavirus RNA Expression in Neoplasia; J.A. DiPaolo, C.H. Woodworth. Mechanisms of Inhibition of Tumor Promotion, Progression, Invasion, and Metastasis: Mechanisms of Inhibition of Tumor Progression; B.S. Warren, T.J. Slaga. Prospects in Chemoprevention of Mutation and Cancer: Dietary Inhibitors Against Mutagenesis and Carcinogenesis; H. Hayatsu, et al. 35 additional articles. Index.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Lifestyle, in any part of the world, is associated with the occurrence of major chronic diseases, including coronary heart disease, hypertension, and stroke; many distinct types of cancer; and adult onset diabetes (11,22,70,75). On…e important element of lifestyle is tobacco use, which appreciably increases the risk of a number of chronic diseases (21). Other lifestyle factors relate to nutritional traditions, alcohol use, and exercise (11,30,58,60,70,71). The underlying evidence is, in part, based on the evidence of specific diseases in relation to dietary habits in a given geographic region, as well as changes in such disease occurrences in migrant populations from a low risk to a high risk area, and vice versa (25,42). Populations that customarily consume fruits and vegetables and also whole grain cereal products generally have a lower risk of cardiovascular diseases and specific types of cancer than populations with a lower intake of such foods, everything else being equal (63). In the last few years, research has provided mechanistic explanations as to the reasons for the protective effects of specific foods. This paper will emphasize the mechanisms whereby cancer risks are reduced by dietary modification. 508 pp. Englisch.
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Antimutagenesis Studies in Japan.- Cancer Prevention: Underlying Principles and Practical Proposals.- Antimutagens in Food.- Anticlastogenic Dietary Factors Assessed in Mammalian Assays.- Antigenotoxic Activity of Carotenoids in Ca…rcinogen-Exposed Populations.- Plant Antimutagens.- Antimutagens and Anticarcinogens in Environmental Toxicology.- Human Biomonitoring in Exposure to Environmental Genotoxicants.- The Concept of Activity Profiles of Antimutagens.- Prevention of Formation of Important Mutagens/Carcinogens in the Human Food Chain.- Free Radicals.- Free Radical Reactions with DNA and its Nucleotides.- Mechanisms of Inactivation of Oxygen Radicals by Dietary Antioxidants and their Models.- Role of Dietary Antioxidants in Protection Against Oxidative Damage.- Antitumor Initiators And Carcinogenesis.- Inhibition of Carcinogenesis by Naturally-occurring and Synthetic Compounds.- Newly Recognized Anticarcinogenic Fatty Acids.- Caloric Restriction in Experimental Carcinogenesis.- Carcinogenicity and Modification of Carcinogenic Response by Antioxidants.- Antitumor Promoters and Carcinogenesis.- Inhibition of Tumor Promotion by DL- -Difluoromethyl-Ornithine, A Specific Irreversible Inhibitor of Ornithine Decarboxylase.- New Antitumor Promoters: (-)-Epigallocatechin Gallate and Sarcophytols A and B.- Chemoprevention of Mammary Cancer by Retinoids.- Aspects Of Mammalian And Human Genetics.- Suppression of Tumor Promotion by Inhibitors of Poly(ADP)ribose Formation.- Antimutagenic Activity of Vitamins in Cultured Mammalian Cells.- Microcell-Mediated Chromosome Transfer: A Strategy for Studying the Genetics and Molecular Pathology of Human Hereditary Diseases with Abnormal Responses to DNA Damage.- Molecular Aspects Of Mutagenesis And Antimutagenesis.- Genetic Analyses ofCellular Functions Required for UV Mutagenesis in Escherichia coli.- Position of a Single Acetylaminofluorene Adduct within a Mutational Hot Spot is Critical for the Related Mutagenic Event.- Fidelity of Animal Cell DNA Polymerases and and of a Human DNA Replication Complex.- Molecular Mechanisms of Replicational Fidelity in Escherichia Coli.- Oncogenes And Antioncogenes.- Permanent Conversion of NIH3T3 Cells Transformed by Activated c-Ha-ras, c-Ki-ras, N-ras, OR c-raf, and of Human Pancreatic Adenocarcinoma Containing Activated c-Ki-ras to Apparently Normal Cells by Treatment with the Antibiotic Azatyrosine.- Oncogenes of Stomach Cancers.- Oncogenic Potential and Normal Function of the Proto-oncogenes Encoding Protein-Tyrosine Kinases.- Short Papers.- Inhibition of the Genotoxicity of 3-Amino-1-Methyl-5H- Pyrido[4,3-b]Indole (Trp-P-2) in Drosophila by Chlorophyll.- Inhibition of Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone (NNK)-Induced Lung Tumors and DNA Methylation in F344 Rats and A/J Mice by Phenethyl Isothiocyanate.- Proteolytic Activation of UmuD and MucA Proteins for SOS Mutagenesis.- Analysis of Bleomycin-resistant DNA Synthesis in Cells from an Inherited Human Disorder, Ataxia Telangiectasia.- Tumor Dose-response Studies with Aflatoxin B1 and the Ambivalent Modulator Indole-3-carbinol: Inhibitory versus Promotional Potency.- Antimutagenesis in Yeast by Sodium Chloride, Potassium Chloride, and Sodium Saccharin.- The Use of Drosophila as an in VIVO System to Study Modifiers of Chemical Mutagenesis.- The Mouse Mutant, 'Wasted': Tissue-specific Radiation Sensitivity and Hematopoietic Cell Lineages.- Antimutagenic Effects of Tumor Promoters-Co-mutagenic Effects of Co-carcinogens.- Antimutagenic Effects of DimethylSulfoxide on Metabolism and Genotoxicity of Benzene in Vivo.- Possible Antitumor Promoter in the Glandular Stomach: Calcium Chloride.- Reversion of Transformed NIH 3T3 Cells to Flat Cells by Inhibitors of Poly(ADP-ribose) Polymerase.- Inactivation of Mutagenic Heterocyclic and Aryl Amines by Linoleic Acid 13-Monohydroperoxide and Methemoglobin.- Establ.
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