emel arinc (41 risultati)

gebundene Ausgabe. Condizione: Gut. 614 S. Das hier angebotene Buch stammt aus einer teilaufgelösten wissenschaftlichen Bibliothek und trägt die entsprechenden Kennzeichnungen (Rückenschild, Instituts-Stempel.); leichte altersbedingte Anbräunung des Papiers; der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. ENGLISCH. Sprache: Englisch Gewicht in Gramm: 950.

Condizione: New. pp. 512.

Condizione: New.

Condizione: New. In.

PF. Condizione: New.

Hardcover. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Taschenbuch. Condizione: Neu. Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds | Emel Arinç (u. a.) | Taschenbuch | 508 S. | Englisch | 2012 | Springer | EAN 9781468472868 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Condizione: New. In.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume represents the proceedings of a NATO Advanced Study Institute on 'Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds' which was held in ~eme (Izmir) Turkey, August 27 to September 7, 1989. The Institute emphasized the potential dangers of drugs, pollutants, pesticides, carcinogens, and both nutrient and non-nutrient food additives and their interactions at the molecular level. These xenobiotics are metabolized in phase I reactions by monooxygenases, primarly cytochrome P450-isozyme dependent, followed by phase II conjugation enzymes. The versatility of these enzymes is unique in biochemistry since they catalyze the metabolism of an almost limitless number of compounds through a diverse array of reactions. Although these metabolic sequences are usually detoxication mechanisms, in some cases the reactive intermediates are more mutagenic, more carcinogenic and ultimately more toxic than the parent compound. The Institute was devoted to recent scientific progress in the understanding of the biochemical and molecular properties of these enzymes and factors that influence the metabolism of chemicals to toxic and non-toxic compounds. Overview lectures focused on xenobiotic metabolism by cytochrome P450, the flavin-containing monooxygenase, cytochrome b5, epoxide hydrolase, glutathione S-transferase and UDP-glucuronosyl transferase. Several additional presentations stressed various aspects of cytochrome P450 mediated metabolism including: specific forms in the rabbit and insects; topology in membranes; posttranslational modification; control of constitutive forms in the rat; hormonal and xenobiotic regulation; prostanoid metabolism; endogenous substrate metabolism; interaction with estrogenic pesticides; pesticide bioactivation. The Institute also included talks on interactions between enzymes and on benzene metabolism and toxicity.

Paperback. Condizione: Like New. Like New. book.

Condizione: New. pp. 636.

Condizione: New. pp. 308.

Taschenbuch. Condizione: Neu. Molecular Aspects of Oxidative Drug Metabolizing Enzymes | Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health | Emel Arinc (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2011 | Springer-Verlag GmbH | EAN 9783642795305 | Verantwortliche Person für die EU: Lauinger, Sonia, Sonia Lauinger, Lauinger Verlag, Heinrich-Köhler-Platz 8, 76187 Karlsruhe, mail[at]lauinger-verlag[dot]de | Anbieter: preigu.

Condizione: New. pp. 308.

Paperback. Condizione: Brand New. 623 pages. 9.00x6.10x1.40 inches. In Stock.

Condizione: New. In.

Condizione: New. In.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.

Taschenbuch. Condizione: Neu. Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes | Emel Arinç (u. a.) | Taschenbuch | viii | Englisch | 2012 | Springer | EAN 9781461372028 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The NATO Advanced Study Institute of 'Molecular and Applied Aspects of Oxida tive Drug Metabolizing Enzymes' was held in Tekirova, Antalya, Turkey, from August 31 to September 11, 1997. This Institute was the third of a series of the NATO ASIs on a similar topic relating to the enzymes of oxidative metabolism of xenobiotics. The first NATO ASI in this series, entitled 'Molecular Aspects of Monooxygenases and Bioactiva tion of Toxic Compounds' (NATO ASI Series A: Life Sciences, Vol. 202), was held in.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The NATO Advanced Study Institute of 'Molecular and Applied Aspects of Oxida tive Drug Metabolizing Enzymes' was held in Tekirova, Antalya, Turkey, from August 31 to September 11, 1997. This Institute was the third of a series of the NATO ASIs on a similar topic relating to the enzymes of oxidative metabolism of xenobiotics. The first NATO ASI in this series, entitled 'Molecular Aspects of Monooxygenases and Bioactiva tion of Toxic Compounds' (NATO ASI Series A: Life Sciences, Vol. 202), was held in.

Paperback. Condizione: Brand New. reprint edition. 302 pages. 10.00x7.00x0.73 inches. In Stock.

Hardcover. Condizione: Brand New. 1st edition. 294 pages. 10.00x6.75x0.75 inches. In Stock.

Paperback. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Hardcover. Condizione: Like New. Like New. book.

Condizione: new. Questo è un articolo print on demand.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume represents the proceedings of a NATO Advanced Study Institute on 'Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds' which was held in ~eme (Izmir) Turkey, August 27 to September 7, 1989. The Institute emphasized the potential dangers of drugs, pollutants, pesticides, carcinogens, and both nutrient and non-nutrient food additives and their interactions at the molecular level. These xenobiotics are metabolized in phase I reactions by monooxygenases, primarly cytochrome P450-isozyme dependent, followed by phase II conjugation enzymes. The versatility of these enzymes is unique in biochemistry since they catalyze the metabolism of an almost limitless number of compounds through a diverse array of reactions. Although these metabolic sequences are usually detoxication mechanisms, in some cases the reactive intermediates are more mutagenic, more carcinogenic and ultimately more toxic than the parent compound. The Institute was devoted to recent scientific progress in the understanding of the biochemical and molecular properties of these enzymes and factors that influence the metabolism of chemicals to toxic and non-toxic compounds. Overview lectures focused on xenobiotic metabolism by cytochrome P450, the flavin-containing monooxygenase, cytochrome b5, epoxide hydrolase, glutathione S-transferase and UDP-glucuronosyl transferase. Several additional presentations stressed various aspects of cytochrome P450 mediated metabolism including: specific forms in the rabbit and insects; topology in membranes; posttranslational modification; control of constitutive forms in the rat; hormonal and xenobiotic regulation; prostanoid metabolism; endogenous substrate metabolism; interaction with estrogenic pesticides; pesticide bioactivation. The Institute also included talks on interactions between enzymes and on benzene metabolism and toxicity. 512 pp. Englisch.

Condizione: New. Print on Demand pp. 512 66:B&W 7 x 10 in or 254 x 178 mm Perfect Bound on White w/Gloss Lam.

Condizione: New. PRINT ON DEMAND pp. 512.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Cytochrome P450-Dependent Monooxygenase: An Overview.- The Flavin-Containing Monooxygenase (EC 1.14.13.8).- Multiple Forms of Rabbit Cytochrome P450: Comparison of Chemical, Physical, Immunological and Biocatalytic Properties.- Primary Structures and Regulation of Cytochrome P450 Isozymes 2 (IIB) and 5 (IVB) and the Flavin-Containing Monooxygenase in Rabbit Liver and Lung.- Insect Cytochrome P450.- I. Membrane Topology of Cytochromes P450: Elements and Measurement by Spectroscopic Techniques.- II. Membrane Topology of Cytochromes P450: Oligomers and Cooperativity.- NADPH-Dependent Cytochrome P450 Reductase A. Y. H. Lu.- Essential Features of NADH Dependent Cytochrome b5 Reductase and Cytochrome b5 of Liver and Lung Microsomes.- Electron Transfer from Cytochrome b5 to Cytochrome P450.- Functional Aspects of Protein-Protein Interactions of Cytochrome P450, Cytochrome b5 and Cytochrome P450 Reductase.- Posttranslational Modification by Phosphorylation: Control of Cytochrome P450 and Associated Enzymes.- Physiological and Pathophysiological Alterations in Rat Hepatic Cytochrome P450.- Ontogenesis of Liver Cytochromes P450.- Mechanism of Steroid Hormome Action A. Berkenstam.- Xenobiotic Regulation of Cytochrome P450 Gene Expression.- Prostanoid Metabolism and Biologically Active Product Formation.- Role of Cytochrome P450 in the Anabolism and Catabolism of Endobiotics.- Interactions of Estrogenic Pesticides with Cytochrome P450.- Effects of Inhibitors on the P450-Dependent Metabolism of Endogenous Compounds in Fungi, Protozoa, Plants and Vertebrates.- Mechanism of Metabolic Activation of Nitroimidozoles.- Benzene Metabolism R. Snyder.- Mechanisms of Benzene Toxicity.- Hematotoxicity, Leukemogenecity and Carcinogenecity of Chronic Exposure to Benzene.- Epoxide Hydrolase Isoenzymes and Their Individual Contribution to the Control of Toxic Metabolites.- Role of the Weil-Known Basic and Recently Discovered Acidic Glutathione S-Transferases in the Control of Genotoxic Metabolites.- Characterisation and Regulation of UDP-Glucuronosyltransferases.- Molecular Cloning, Expression and Genetic Deficiencies of UDP-Glucuronosyltransferases.- Contributors.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 512 pp. Englisch.