eugene j h wee (30 risultati)

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Taschenbuch. Condizione: Neu. Promoter DNA Methylation of miRNAs as Breast Cancer Biomarkers | From biomarker discovery to biotechnology development | Eugene J. H. Wee | Taschenbuch | 188 S. | Englisch | 2013 | LAP LAMBERT Academic Publishing | EAN 9783659505072 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

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Condizione: Used. pp. 210.

Condizione: Used. pp. 210.

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Hardcover. Condizione: new. Hardcover. In recent years, thousands of cancer biomarkers have been discovered and described in scientific literature. The promise of personalised medicine, where diseases such as cancer are accurately diagnosed and treatments tailored specifically for individuals, is becoming a reality. Significant advances in biomarker-based research methodologies such as Next Generation Sequencing (NGS) are at the cusp of ushering in a new era of personal medicine. However, unlike the spectacular advances in research technologies for disease biomarker discovery, biomarker-based technologies that can effectively be used in the clinic (or point-of-care) to enable personalised medicine are still lacking. In this book, we feature a selection of emerging technologies which are aimed at enabling clinical applications of personalised medicine. Each of the eight chapters is written by a leading group at the intersection of microfluidics, biology, and nanotechnology.For instance, to accelerate a major bottleneck in the development of clinically useful protein diagnostics, we discuss the application of yeast-derived single chain Fragment variable (scFv) antibody-like molecules as a potential low cost alternative to traditional antibody-based diagnostics. Circulating tumour cells (CTCs) are an emerging class of cancer biomarkers and a potential resource for understanding cancer progression; we explore various strategies combining microfluidics with nanotechnology for capturing CTCs. The book includes an evaluation of some current and emerging technologies for detecting clinical DNA methylation, another potential cancer biomarker. As personalised medicine may involve tracking a patient's response to treatment, the application of microfluidics to detect metabolites in biological fluids is also discussed. Finally, the ultimate goal of personalised medicine is targeted therapy. One promising approach is RNAi technology which uses short nucleotides to disrupt cancer pathways. In this book, nanoparticle approaches to deliver these short nucleotides are discussed. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

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Condizione: New. Editor(s): Shiddiky, Muhammad J. A.; Wee, Eugene J. H.; Rauf, Sakandar; Trau, Matt. Num Pages: 227 pages. BIC Classification: MBGR. Category: (P) Professional & Vocational. Dimension: 258 x 183 x 18. Weight in Grams: 556. . 2013. 1st Edition. Hardcover. . . . .

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Condizione: New. KlappentextrnrnIn recent years, thousands of cancer biomarkers have been discovered and described in scientific literature. The promise of personalised medicine, where diseases such as cancer are accurately diagnosed and treatments tailored spec.

Condizione: New. Editor(s): Shiddiky, Muhammad J. A.; Wee, Eugene J. H.; Rauf, Sakandar; Trau, Matt. Num Pages: 227 pages. BIC Classification: MBGR. Category: (P) Professional & Vocational. Dimension: 258 x 183 x 18. Weight in Grams: 556. . 2013. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland.

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Buch. Condizione: Neu. Neuware - In recent years, thousands of cancer biomarkers have been discovered and described in scientific literature. The promise of personalised medicine, where diseases such as cancer are accurately diagnosed and treatments tailored specifically for individuals, is becoming a reality. Significant advances in biomarker-based research methodologies such as Next Generation Sequencing (NGS) are at the cusp of ushering in a new era of personal medicine. However, unlike the spectacular advances in research technologies for disease biomarker discovery, biomarker-based technologies that can effectively be used in the clinic (or point-of-care) to enable personalised medicine are still lacking. In this book, we feature a selection of emerging technologies which are aimed at enabling clinical applications of personalised medicine. Each of the eight chapters is written by a leading group at the intersection of microfluidics, biology, and nanotechnology. For instance, to accelerate a major bottleneck in the development of clinically useful protein diagnostics, we discuss the application of yeast-derived single chain Fragment variable (scFv) antibody-like molecules as a potential low cost alternative to traditional antibody-based diagnostics. Circulating tumour cells (CTCs) are an emerging class of cancer biomarkers and a potential resource for understanding cancer progression; we explore various strategies combining microfluidics with nanotechnology for capturing CTCs. The book includes an evaluation of some current and emerging technologies for detecting clinical DNA methylation, another potential cancer biomarker. As personalised medicine may involve tracking a patient's response to treatment, the application of microfluidics to detect metabolites in biological fluids is also discussed. Finally, the ultimate goal of personalised medicine is targeted therapy. One promising approach is RNAi technology which uses short nucleotides to disrupt cancer pathways. In this book, nanoparticle approaches to deliver these short nucleotides are discussed.

Hardcover. Condizione: new. Hardcover. In recent years, thousands of cancer biomarkers have been discovered and described in scientific literature. The promise of personalised medicine, where diseases such as cancer are accurately diagnosed and treatments tailored specifically for individuals, is becoming a reality. Significant advances in biomarker-based research methodologies such as Next Generation Sequencing (NGS) are at the cusp of ushering in a new era of personal medicine. However, unlike the spectacular advances in research technologies for disease biomarker discovery, biomarker-based technologies that can effectively be used in the clinic (or point-of-care) to enable personalised medicine are still lacking. In this book, we feature a selection of emerging technologies which are aimed at enabling clinical applications of personalised medicine. Each of the eight chapters is written by a leading group at the intersection of microfluidics, biology, and nanotechnology.For instance, to accelerate a major bottleneck in the development of clinically useful protein diagnostics, we discuss the application of yeast-derived single chain Fragment variable (scFv) antibody-like molecules as a potential low cost alternative to traditional antibody-based diagnostics. Circulating tumour cells (CTCs) are an emerging class of cancer biomarkers and a potential resource for understanding cancer progression; we explore various strategies combining microfluidics with nanotechnology for capturing CTCs. The book includes an evaluation of some current and emerging technologies for detecting clinical DNA methylation, another potential cancer biomarker. As personalised medicine may involve tracking a patient's response to treatment, the application of microfluidics to detect metabolites in biological fluids is also discussed. Finally, the ultimate goal of personalised medicine is targeted therapy. One promising approach is RNAi technology which uses short nucleotides to disrupt cancer pathways. In this book, nanoparticle approaches to deliver these short nucleotides are discussed. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Breast cancer is a complex disease with many factors that can contribute to its development. As such, informative biomarkers are required to accurately and comprehensively characterize breast cancer so that patient management is both informed and optimal. Current breast cancer biomarkers, although useful, have limitations and are sometimes unable to classify all breast cancer patients. Therefore, new classes of biomarkers and detection tools are needed. A possible complement to existing biomarkers is the aberrant DNA methylation of miRNA promoters in breast cancer. This book will take the reader on a journey from discovering a novel biomarker to developing a new technology for detecting this potential biomarker in clinical practice. The genetics/biotechnology interdisciplinary combination may appeal to readers majoring in either field and to anyone interested in interdisciplinary research. 188 pp. Englisch.

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Wee Eugene J.H.Eugene J.H. Wee, PhD in cancer genetics from The University of Queensland, Australia. Postdoctoral researcher at the Australian Institute for Bioengineering and Nanotechnology.Breast cancer is a complex disease wit.

Condizione: New. Print on Demand pp. 188 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Condizione: New. PRINT ON DEMAND pp. 188.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Breast cancer is a complex disease with many factors that can contribute to its development. As such, informative biomarkers are required to accurately and comprehensively characterize breast cancer so that patient management is both informed and optimal. Current breast cancer biomarkers, although useful, have limitations and are sometimes unable to classify all breast cancer patients. Therefore, new classes of biomarkers and detection tools are needed. A possible complement to existing biomarkers is the aberrant DNA methylation of miRNA promoters in breast cancer. This book will take the reader on a journey from discovering a novel biomarker to developing a new technology for detecting this potential biomarker in clinical practice. The genetics/biotechnology interdisciplinary combination may appeal to readers majoring in either field and to anyone interested in interdisciplinary research.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 188 pp. Englisch.

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Breast cancer is a complex disease with many factors that can contribute to its development. As such, informative biomarkers are required to accurately and comprehensively characterize breast cancer so that patient management is both informed and optimal. Current breast cancer biomarkers, although useful, have limitations and are sometimes unable to classify all breast cancer patients. Therefore, new classes of biomarkers and detection tools are needed. A possible complement to existing biomarkers is the aberrant DNA methylation of miRNA promoters in breast cancer. This book will take the reader on a journey from discovering a novel biomarker to developing a new technology for detecting this potential biomarker in clinical practice. The genetics/biotechnology interdisciplinary combination may appeal to readers majoring in either field and to anyone interested in interdisciplinary research.