Fielden e m (42 risultati)
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Da: BoundlessBookstore, Wallingford, Regno UnitoBoundlessBookstore
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Condizione: Good. Good condition book without dust jacket. Boards are clean with minor wear. Book has clean and bright contents.
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Selective Activation of Drugs by Redox Processes
Adams, G. E.; Breccia, A.; Fielden, E. M.; Wardman, P. (eds.)
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Da: PsychoBabel & Skoob Books, Didcot, Regno UnitoPsychoBabel & Skoob Books
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Hardcover. Condizione: Very Good. Hardcover (no dust jacket; printed boards). Very good condition. From the offices of a world-leading nuclear medicine research establishment. Spine ends are a little bumped. Stamps on page block, pastedowns and title-page. Pages are sound and clear. TA. Used.
Editore: Oak Ridge National Laboratory, 1981, 640 Pp., 1981
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Aggiungi al carrelloSoft Cover. Condizione: Good. Softcovers; light creasing of wraps and leaves; o/w in good condition. This is a heavy book; extra shipping may be required for priority mail or international orders.
Lingua: Inglese
Editore: Springer-Verlag New York, Incorporated, New York, NY, U.S.A., 1991
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Laminated Boards. Condizione: Good +. No Jacket. 430pp. Please ignore Abebooks "stock image" of this book.
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Da: PsychoBabel & Skoob Books, Didcot, Regno UnitoPsychoBabel & Skoob Books
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Hardcover. Condizione: Good. Condizione sovraccoperta: Good. Hardcover. Ex-library. Dust jacket is protected with clear plastic sleeve. A few marks and scores on sleeve. Jacket leading corners, edges and spine ends are slightly worn. Shelfmark on jacket spine. Hardcover spine ends are a little bumped. Library stamps on page bloc…k and title page. Library label on FEP. Binding is intact, contents are clean and clear. AM. Ex-Library.
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Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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Paperback. Condizione: New.
Selective Activation of Drugs by Redox Processes
Adams, G. E. (Editor)/ Breccia, A. (Editor)/ Fielden, E. M. (Editor)/ Wardman, P. (Editor)
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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Paperback. Condizione: Brand New. 372 pages. 10.00x7.00x0.78 inches. In Stock.
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Da: Roland Antiquariat UG haftungsbeschränkt, Weinheim, GermaniaRoland Antiquariat UG haftungsbeschränkt
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Hardcover. 430 Seiten Good condition. Reading pages are clean and without marks. Retired library exemplar, with the usual marking. Corners slightly rubbed or bumped. 9783540517801 Sprache: Englisch Gewicht in Gramm: 880.
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Da: Bernhard Kiewel Rare Books, Grünberg, GermaniaBernhard Kiewel Rare Books
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25 x 17. 441 Seiten. Hardcover. Ordnungsgemäß aus einer Universitäts-Bibliothek ausgesondert (Stempel, Rückenschild). Guter Zustand. Sprache: Englisch Gewicht in Gramm: 900.
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Da: Antiquariat Silvanus - Inhaber Johannes Schaefer, Ahrbrück, GermaniaAntiquariat Silvanus - Inhaber Johannes Schaefer
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430 S. mit zahlreichen Abbildungen, (430 pp. with a lot of figures), Proceedings of the NATO Advanced Research Workshop on The Early Effects of Radiation on DNA held at San Marino, Italy, May 7-11, 1990. 3540517804 Sprache: Englisch Gewicht in Gramm: 880 Groß 8°, Original-Pappband, sehr gutes Exemplar, (hard cover, fine copy).
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Da: GreatBookPrices, Columbia, MD, U.S.A.GreatBookPrices
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Da: California Books, Miami, FL, U.S.A.California Books
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This Workshop, under the auspices of the NATO Advanced Research Workshop program, was organised to review the current status of research into redox-activated compounds particularly bioreductive drugs, and their applications in various fields of me…dicine, both as diagnostic and therapeutic agents. The Workshop brought together key workers in this currently expanding field of research, i.e. clinici ans, pharmacologists, biochemists and molecular scientists. The programme consisted of several sections including general review lectures, presentations of laboratory-based and clinical research, some poster presentations and general 'round table' discussions. The topics ranged from oxygen effects in biological processes, the nature and function of redox proteins particularly those involved in drug activation, the bioactivation of drugs used as sensitizers in radiation oncology, novel approaches to anti-cancer chemotherapy, anti-bacterial agents, non-steroidal anti-inflammatory drugs, anti-oxidants and varous clinical applications of chemical modifiers. G.E. ADAMS A. BRECCIA E.M. FIELDEN P. WARDMAN v ACKNOWLEDGEMENTS The Organisers gratefully acknowledge the following for their generous financial support: ARW-NATO Comune di Fermo, Italy Cas sa di Risparmio di Fermo Istituto di Scienze Chimiche, Bologna, Italy Pharm. Group ALFA, r,assermann, Schiapparplli, Italy Sadam Indu~tr ie.-' Pharmex Corp., Bologna, Italy vii CONTENTS Characteristics of Hypoxic Cells that Enhance their Susceptibility to Chemical Injury . . . .
Da: Xerxes Fine and Rare Books and Documents, Glen Head, NY, U.S.A.Xerxes Fine and Rare Books and Documents
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Aggiungi al carrelloCondizione: VG. London 1987. Lg.8vo., 985pp., index, printed boards, VG. Volume 2 only.
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Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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Da: GreatBookPricesUK, Woodford Green, Regno UnitoGreatBookPricesUK
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RADIATION RESEARCH: PROCEEDINGS OF THE 8TH INTERNATIONAL CONGRESS OF RADIATION RESEARCH EDINBURGH, JULY 1987 - Volume 2
E M and J F Fowler and J H Hendry and D Scott (editors) Fielden
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Da: CSG Onlinebuch GMBH, Darmstadt, GermaniaCSG Onlinebuch GMBH
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Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Characteristics of Hypoxic Cells that Enhance their Susceptibility to Chemical Injury.- Prediction and Measurement of Redox Properties of Drugs and Biomolecules.- Metal-Catalyzed Redox Processes in Biological Systems and Drug Activation.- Redox Systems G…enerated by Electro-chemical Oxidations and Reductions.- The Rôle of DNA Damage in the Bioreductive Action of 2-Nitroimidazoles.- Redox Properties of Radiation Induced Free Radicals.- Reduction of Bleomycin-Fe by Reductases and Active Oxygen Formation.- Redox Activation of Drugs by the Red Blood Cell Membrane.- Induction of Stress Proteins and Drug Resistance by Hypoxia and Applications of Magnetic Resonance Spectroscopy and Cryospectrophotometry for Detecting Hypoxia in Tumors.- Mechanisms of Activation of Mitomycin C and AZQ in Aerobic and Hypoxic Mammalian Cells.- Molecular Interactions and Biological Effects of the Products of Reduction of Nitroimidazoles.- Redox Activation of Benzotriazine N-oxides: Mechanisms and Potential as Anticancer Drugs.- Nitroacridines and Nitroquinolines as DNA-affinic Hypoxia-selective Cytotoxins.- Metabolic Effects of Hypoxic Cell Sensitizers.- Does Ro-03-8799 Concentration in Human Tumour Xenografts Predict Radiosensitization Comparison with SR-2508.- Enzyme-directed Bioreductive Drug Development.- Improved Treatment of Tumours in vivo by Combining the Bioreductive Drug, RSU-1069, Hydralazine and Hyperthermia.- Assessment of Bioreductive Drug Toxicity in vitro and in Experimental Tumours in vivo.- Activity of Bioreductive Agents in Human and Rodent Tumor Cells.- The Control of Tumour Oxygenation in Mice: The Importance of Tumour Site.- Critical Events in the Toxicity of Redox Active Drugs.- The Reductive Activation of Nitroimidazoles; Modification by Oxygen and other Redox-active Molecules in Cellular Systems.- Fluorescent Probes for Hypoxia: Chemical Aspects.- Toxicity of Metal Complexes with Radiosensitizing Properties.- Effects on DNA of Bioreducible Nitroimidazole and Benzotriazine Drugs.- Response of Repair and Reduction Deficient Mutants to Agents Requiring Bioreduction.- Bioreductive Drugs and Radiation: Pharmacokinetics and Clinical Trials of Etanidazole Radiosensitizer.- The Oncogenic Potential of Bioreductive Drugs.- Adduct Formation by 2-Nitroimidazole in Mammalian Cells: Optimization of Markers for Tissue Oxygenation.- Tumour Blood Flow and its Modulation: Implications for Bioreductive Drug Activity in vivo.- Poster Presentations.- Participants.
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Gebunden. Condizione: New. KlappentextReviews the current state of research into redox-activated compounds, particularly bioreductive drugs, and their applications in various fields of medicine as both diagnostic and therapeutic agents. Among the topics considered.
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Da: CSG Onlinebuch GMBH, Darmstadt, GermaniaCSG Onlinebuch GMBH
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Hardcover. Condizione: Brand New. 1st edition. 370 pages. 10.00x6.75x1.00 inches. In Stock.
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Paperback. Condizione: Brand New. 430 pages. 9.40x6.80x1.10 inches. In Stock.
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Condizione: New. Proceedings of the Nato Advanced Research Workshop on The Early Effects of Radiation on DNA held at San Miniato, Italy, May 7-11, 1990Interest in the biological effects of ionising radiation closely followed the identification of such radiation. The rea.
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Hardcover. Condizione: new. Hardcover. Characteristics of Hypoxic Cells that Enhance their Susceptibility to Chemical Injury.- Prediction and Measurement of Redox Properties of Drugs and Biomolecules.- Metal-Catalyzed Redox Processes in Biological Systems and Drug Activation.- Redox Systems Generated by Electro-chemical Oxidatio…ns and Reductions.- The Role of DNA Damage in the Bioreductive Action of 2-Nitroimidazoles.- Redox Properties of Radiation Induced Free Radicals.- Reduction of Bleomycin-Fe by Reductases and Active Oxygen Formation.- Redox Activation of Drugs by the Red Blood Cell Membrane.- Induction of Stress Proteins and Drug Resistance by Hypoxia and Applications of Magnetic Resonance Spectroscopy and Cryospectrophotometry for Detecting Hypoxia in Tumors.- Mechanisms of Activation of Mitomycin C and AZQ in Aerobic and Hypoxic Mammalian Cells.- Molecular Interactions and Biological Effects of the Products of Reduction of Nitroimidazoles.- Redox Activation of Benzotriazine N-oxides: Mechanisms and Potential as Anticancer Drugs.- Nitroacridines and Nitroquinolines as DNA-affinic Hypoxia-selective Cytotoxins.- Metabolic Effects of Hypoxic Cell Sensitizers.- Does Ro-03-8799 Concentration in Human Tumour Xenografts Predict Radiosensitization? Comparison with SR-2508.- Enzyme-directed Bioreductive Drug Development.- Improved Treatment of Tumours in vivo by Combining the Bioreductive Drug, RSU-1069, Hydralazine and Hyperthermia.- Assessment of Bioreductive Drug Toxicity in vitro and in Experimental Tumours in vivo.- Activity of Bioreductive Agents in Human and Rodent Tumor Cells.- The Control of Tumour Oxygenation in Mice: The Importance of Tumour Site.- Critical Events in the Toxicity of Redox Active Drugs.- The Reductive Activation of Nitroimidazoles; Modification by Oxygen and other Redox-active Molecules in Cellular Systems.- Fluorescent Probes for Hypoxia: Chemical Aspects.- Toxicity of Metal Complexes with Radiosensitizing Properties.- Effects on DNA of Bioreducible Nitroimidazole and Benzotriazine Drugs.- Response of Repair and Reduction Deficient Mutants to Agents Requiring Bioreduction.- Bioreductive Drugs and Radiation: Pharmacokinetics and Clinical Trials of Etanidazole Radiosensitizer.- The Oncogenic Potential of Bioreductive Drugs.- Adduct Formation by 2-Nitroimidazole in Mammalian Cells: Optimization of Markers for Tissue Oxygenation.- Tumour Blood Flow and its Modulation: Implications for Bioreductive Drug Activity in vivo.- Poster Presentations.- Participants. Reviews the current state of research into redox-activated compounds, particularly bioreductive drugs, and their applications in various fields of medicine as both diagnostic and therapeutic agents. Among the topics considered are the oxygen effects of biological processes; the nature and function o Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.
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Hardcover. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
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Lingua: Inglese
Editore: Springer, Berlin, Springer Berlin Heidelberg, Springer, 2011
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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Taschenbuch. Condizione: Neu. Neuware - Interest in the biological effects of ionising radiation closely followed the identification of such radiation. The realisation that DNA is the site of genetic infonnation in cells subsequently focussed attention on DNA as an important target in the lethal and mutagenic effects of ionising… radiation. Thus radiation effects upon DNA became an important area for fundamental scientific studies by radiation biologists, chemists and physicists. To a first approximation, the concerns of the three disciplines can be divided by time scales: the physical process of energy deposition from photon or charged 16 12 particle and subsequent relaxation (-10- to 10- secs), followed by chemical 12 2 reactions (- 10- to 10 secs), and fmally, the expression of biological effect (minutes to years). Thus, the concept of 'early processes' conveys different ideas to different scientists, although they are all interrelated. To attempt to describe in any detail all these processes is a mammoth task which is not made easier by the different conventions and experimental approaches of the three disciplines. However, the recent advances in all these scientific areas seemed, to the organisers at least, to offer the opportunity to stimulate more active interaction between physicists, chemists and biologists. With this in mind, a multi-disciplinary workshop was organised, which brought together some fifty scientists to present their own specialist interests and, through extensive discussion, explore which problems are of high priority and require input from the different disciplines to resolve them.
