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Hardcover. Condizione: Very Good. No Jacket. 3540210954. Ex library, hardcover. 581 pages, index, illustrated with charts, tables and diagrams. Examines transcription factors as key players in the execution of the genomic program of any given cell. Focusess on the role of transcription factors in cellular transformation and cancer, other chapters highlight the contributions of transcription factors to inflammatory responses or xenobiotic responses. The text illustrates how a viral transcription factor interferes with the physiology of its host cell and finally points out out future research. Contents as new, clean, tight and bright. Book.

Hardcover. Condizione: Fine. 3540210954. Ex library, hardcover. Lending record shows this book has been borrowed once only. 581 pages, index, illustrated with charts, tables and diagrams. Examines transcription factors as key players in the execution of the genomic program of any given cell. Focusess on the role of transcription factors in cellular transformation and cancer, other chapters highlight the contributions of transcription factors to inflammatory responses or xenobiotic responses. The text illustrates how a viral transcription factor interferes with the physiology of its host cell and finally points out out future research. Contents as new, clean, tight and bright. Book.

Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.

Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

Condizione: New. pp. 596.

Condizione: New. pp. 596 Illus.

Condizione: New. pp. 596.

Condizione: New. In.

Condizione: New. In.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Transcription factors are key players in the execution of the genomic program of any given cell. Their control over complex patterns of gene expression governs essentially every step in the development, growth and differentiation of an organ ism as well as its physiological responses to external stimuli. An Introduction to Transcription Factors, the first part of this volume, de scribes the varied and combinatorial mechanisms involved in the two basic modes of transcriptional control, activation (the chapter by Herrera et al.) and repression (the chapter by Arnosti). Overlaying both modes is an emerging emphasis on epigenetic regulation that uses intricate patterns of chromatin modi fication. Although many of these mechanisms have been elucidated by studying prototypical genes or transcription factors, the recently developed tools of ge nomic biology allow us to unravel the complexity of global transcriptional pro grams with an ever-increasing speed and accuracy (the chapter by Zacharewski and La Pres). Given the central role that transcription factors playas relays positioned be tween the genome and the intracellular and extracellular signals to which cells must respond, it is not surprising that these regulatory proteins playa major role in pathological processes. Part 2 of this volume, Transcription Factors in Patho physiology, introduces a selection of specific transcription factors and their families. Each of these factors has a well-established function in basic cellular mechanisms that, upon dysregulation, can cause or contribute to human disease.

Gebunden. Condizione: New. With contributions by numerous expertsPart 1: An Introduction to Transcription Factors.- Mechanisms of Transcriptional Activation In Eukaryotes. Multiple Mechanisms of Transcriptional Repression in Eukaryotes. Genomics and Transcription Factors.- Part 2.

Paperback. Condizione: Brand New. 596 pages. 9.10x6.00x1.30 inches. In Stock.

Hardcover. Condizione: Brand New. 1st edition. 581 pages. 9.25x6.25x0.75 inches. In Stock.

Buch. Condizione: Neu. Neuware - 1. An Introduction to Transcription Factors.- Mechanisms of Transcriptional Activation in Eukaryotes.- Multiple Mechanisms of Transcriptional Repression in Eukaryotes.- Genomic Approaches to the Study of Transcription Factors.- 2. Transcription Factors in Pathophysiology.- Biological Roles of the STAT Family in Cytokine Signaling.- Members of the T-Cell Factor Family of DNA-Binding Proteins and Their Roles in Tumorigenesis.- Transcription Factors in the Control of Tumor Development and Progression by TGF- Signaling.- The p53 Transcription Factor as Ther apeutic Target in Cancer.- The Role of Ets Transcription Factors in Mediating Cellular Transformation.- Function of the E2F Transcription Factor Family During Normal and Pathological Growth.- c-Myc in Cellular Transformation and Cancer.- NF- B: Critical Regulator of Inflammation and the Immune Response.- Hepatitis BVirus X Protein: Structure-Function Relationships and Role in Viral Pathogenesis.- Regulation of Xenobiot ic Detoxification by PXR, CAR, GR, VDR and SHP Receptors: Consequences in Physiology.- 3. Exogenous Control of Transcription Factor Activity.- Potential of Transcription Factor Decoy Oligonucleotides as Therapeutic Approach.- Selective Estrogen Receptor Modulators as Therapeutic Agents in Breast Cancer Treatment.- Artificial Zinc Finger Peptides: A Promising Tool in Biotechnology and Medicine.- Tetracycline-Controlled Transactivators and Their Potential Use in Gene Therapy Applications.- Modulating Transcript ion with Artificial Regulators.

Hardcover. Condizione: Like New. Like New. book.

Condizione: new. Questo è un articolo print on demand.

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. With contributions by numerous expertsPart 1: An Introduction to Transcription Factors.- Mechanisms of Transcriptional Activation In Eukaryotes. Multiple Mechanisms of Transcriptional Repression in Eukaryotes. Genomics and Transcription Factors.- Part 2.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -1. An Introduction to Transcription Factors.- Mechanisms of Transcriptional Activation in Eukaryotes.- Multiple Mechanisms of Transcriptional Repression in Eukaryotes.- Genomic Approaches to the Study of Transcription Factors.- 2. Transcription Factors in Pathophysiology.- Biological Roles of the STAT Family in Cytokine Signaling.- Members of the T-Cell Factor Family of DNA-Binding Proteins and Their Roles in Tumorigenesis.- Transcription Factors in the Control of Tumor Development and Progression by TGF- Signaling.- The p53 Transcription Factor as Ther apeutic Target in Cancer.- The Role of Ets Transcription Factors in Mediating Cellular Transformation.- Function of the E2F Transcription Factor Family During Normal and Pathological Growth.- c-Myc in Cellular Transformation and Cancer.- NF- B: Critical Regulator of Inflammation and the Immune Response.- Hepatitis BVirus X Protein: Structure-Function Relationships and Role in Viral Pathogenesis.- Regulation of Xenobiot ic Detoxification by PXR, CAR, GR, VDR and SHP Receptors: Consequences in Physiology.- 3. Exogenous Control of Transcription Factor Activity.- Potential of Transcription Factor Decoy Oligonucleotides as Therapeutic Approach.- Selective Estrogen Receptor Modulators as Therapeutic Agents in Breast Cancer Treatment.- Artificial Zinc Finger Peptides: A Promising Tool in Biotechnology and Medicine.- Tetracycline-Controlled Transactivators and Their Potential Use in Gene Therapy Applications.- Modulating Transcript ion with Artificial Regulators.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 596 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Transcription factors are key players in the execution of the genomic program of any given cell. Their control over complex patterns of gene expression governs essentially every step in the development, growth and differentiation of an organ ism as well as its physiological responses to external stimuli. An Introduction to Transcription Factors, the first part of this volume, de scribes the varied and combinatorial mechanisms involved in the two basic modes of transcriptional control, activation (the chapter by Herrera et al.) and repression (the chapter by Arnosti). Overlaying both modes is an emerging emphasis on epigenetic regulation that uses intricate patterns of chromatin modi fication. Although many of these mechanisms have been elucidated by studying prototypical genes or transcription factors, the recently developed tools of ge nomic biology allow us to unravel the complexity of global transcriptional pro grams with an ever-increasing speed and accuracy (the chapter by Zacharewski and La Pres). Given the central role that transcription factors playas relays positioned be tween the genome and the intracellular and extracellular signals to which cells must respond, it is not surprising that these regulatory proteins playa major role in pathological processes. Part 2 of this volume, Transcription Factors in Patho physiology, introduces a selection of specific transcription factors and their families. Each of these factors has a well-established function in basic cellular mechanisms that, upon dysregulation, can cause or contribute to human disease. 596 pp. Englisch.