H j muller eberhard (34 risultati)

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  • Altre immagini

    Lingua: Tedesco

    Editore: Springer-Verlag, 1974

    3540065741 / 9783540065746

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  • Editore: , Il pensiero scientifico (Roma), 1971

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    rilegato. Condizione: Good. Buono stato. Opera in due volumi. Rilegatura editoriale in cartoncino uso tela. Sovraccoperta a colori con alette (con strappo al primo volume). Medicina P A Miescher H J Muller Eberhard TRATTATO DI IMMUNOPATOLOGIA Il pensiero scientifico (Roma) 1971 Medicina Buono (Good) . Book. …

  • Lingua: Inglese

    Editore: Springer, 1982

    3540117385 / 9783540117384

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  • Lingua: Inglese

    Editore: Springer, 1980

    3540103546 / 9783540103547

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  • Lingua: Inglese

    Editore: Springer, 1980

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  • Lingua: Inglese

    Editore: Springer, 1985

    3540150757 / 9783540150756

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  • Lingua: Inglese

    Editore: Springer, 1985

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  • Lingua: Inglese

    Editore: Springer, 1982

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  • Lingua: Inglese

    Editore: Springer, 1982

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    Condizione: New. In English.

  • Lingua: Inglese

    Editore: Springer, 1985

    3540150757 / 9783540150756

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    Condizione: New. In English.

  • Lingua: Inglese

    Editore: Springer, 1982

    3540117385 / 9783540117384

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    Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Peter A. Miescher The skin has always been one of the major targets to clinicians interested in immunology. Initially, the main focus was centred on allergic conditions such as contact hypersensitivity and urticeria. Gradually, the spectrum of immunological conditions involving the skin increased, encompassing diseases such as Dermatitis Herpetiformis, Erythema Muitiforme, Cutaneous Bullous Disorders and Photo toxic Reactions. It has been the intention of the editors of Springer Seminars in Immu nopathology to cover the broad spectrum of immune phenomena encountered in dermatological diseases with special emphasis to newer developments in Immunopathology. Dr. 1. N. Gigli has managed to assemble a series of important contributions within two issues of the Journal which are of such an interest to dermatologists that we decided to publish this topic as a separate volume for all dermatologists who do not have access to Seminars in Immunopathology. 3 Immunologically Mediated Epidermal Cell Injury Richard D. Sontheimer\* and James N. Gilliam Division of Dermatology, University of Texas Health Science Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235, USA Introduction The epidermis is a functional unit of different cell types that has the critical role of protecting man from his environment. The three major cell types that make up the epidermis (keratinocytes, melanocytes, and Langerhans cells) serve different protective functions. The vast majority of epidermal cells are keratinocytes (Fig. 1). …

  • Lingua: Inglese

    Editore: Springer, 1985

    3540150757 / 9783540150756

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    Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Activation of the complement system gives rise to a number of molecular species which can interact with host-derived cells and regulate their function. This interaction is mediated through distinct cell surface complement receptors, and receptor engagement produces biologic responses which can either modulate host defense reactions or enhance inflammation. Although the first complement receptor was recognized more than 30 years ago [80J, detailed biochemical information concerning the receptors has only recently become available. Currently, eight distinct complement receptors are recognized. Five receptors (CRl, CR2, CR3, C3a receptor, and C3e receptor) react with various regions on C3 while the other receptors display specificity for Clq, C5a, or Factor H. This chapter focusses on the chemistry of the various ligands and receptors and discusses the biologic activities which arise as a result of receptor-ligand interaction. II. CIQ Receptor A. The Ligand Clq is the recognition molecule of the classical complement pathway [reviewed in 20, 130]. In serum, it is part of a calcium-dependent penta molecular complex containing one molecule ofClq and two molecules each of the pro enzymes Clr and CIs. During classical pathway activation, the macromolecular complex becomes associated with the activator through the Clq subcomponent. Bound Clq undergoes a conformational change and induces the proteolytic autoactivation of Clr which in turn effects the proteolytic activation of CIs. This process is controlled by the Cl inhibitor (ClINH) which binds irreversibly to activated Clr and CIs, and inhibits their enzymatic activities.…

  • Lingua: Inglese

    Editore: Springer, 1985

    3540150757 / 9783540150756

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    Condizione: New. pp. 484.

  • Lingua: Inglese

    Editore: Springer, 1982

    3540117385 / 9783540117384

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    Condizione: New. pp. 196.

  • Lingua: Inglese

    Editore: Springer, 1982

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    Paperback. Condizione: Brand New. illustrated edition. 196 pages. 9.61x6.54x0.55 inches. In Stock.

  • Lingua: Inglese

    Editore: Springer Berlin Heidelberg, 1980

    3540103546 / 9783540103547

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    Condizione: New. The discovery of specifically acquired immunity which followed the major contributions of Louis Pasteur completely over-shadowed the first studies of the host s natural resistance. Later, the exquisite sensitivity and precision of antigen-antibody reactions.

  • Lingua: Inglese

    Editore: Springer Berlin Heidelberg, 1985

    3540150757 / 9783540150756

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    Paperback. Condizione: Brand New. 1st edition. 480 pages. 9.61x6.69x1.09 inches. In Stock.

  • Lingua: Inglese

    Editore: Springer, 1985

    3540150757 / 9783540150756

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    Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 484 | Sprache: Englisch | Produktart: Bücher | Activation of the complement system gives rise to a number of molecular species which can interact with host-derived cells and regulate their function. This interaction is mediated through distinct cell surface complement receptors, and receptor engagement produces biologic responses which can either modulate host defense reactions or enhance inflammation. Although the first complement receptor was recognized more than 30 years ago [80J, detailed biochemical information concerning the receptors has only recently become available. Currently, eight distinct complement receptors are recognized. Five receptors (CRl, CR2, CR3, C3a receptor, and C3e receptor) react with various regions on C3 while the other receptors display specificity for Clq, C5a, or Factor H. This chapter focusses on the chemistry of the various ligands and receptors and discusses the biologic activities which arise as a result of receptor-ligand interaction. II. CIQ Receptor A. The Ligand Clq is the recognition molecule of the classical complement pathway [reviewed in 20, 130]. In serum, it is part of a calcium-dependent penta molecular complex containing one molecule ofClq and two molecules each of the pro enzymes Clr and CIs. During classical pathway activation, the macromolecular complex becomes associated with the activator through the Clq subcomponent. Bound Clq undergoes a conformational change and induces the proteolytic autoactivation of Clr which in turn effects the proteolytic activation of CIs. This process is controlled by the Cl inhibitor (ClINH) which binds irreversibly to activated Clr and CIs, and inhibits their enzymatic activities.…

  • Lingua: Inglese

    Editore: Springer, 1985

    3540150757 / 9783540150756

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    Paperback. Condizione: Very Good. Dust Jacket may NOT BE INCLUDED.CDs may be missing. SHIPS FROM MULTIPLE LOCATIONS. book.

  • Lingua: Inglese

    Editore: Springer, 1982

    3540117385 / 9783540117384

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  • Klinische Pathophysiologie [Gebundene Ausgabe] Klinisch-pathologische Konferenz Klinische Fächer HumanMedizin Klinikum medizinische Fächer Innere Medizin IntensivMedizin Allgemeinmedizin Pathophysiologie Studium Humanmediziner 2. Studienabschnitt Stoffwechsel Innere Sekretion Blut Immunsystem Infektion Kreislauf Lunge Atmung Verdauung Niere ableitende Harnwege Bewegungsapparat Nervensystem Neoplasien Physiologie Krankheitsbilder Medizin Walter Siegenthaler (Herausgeber), Hubert Erich Blum (Herausgeber)

    Walter Siegenthaler Hubert Erich Blum Beatrice Amann-Vesti, Christian Arnold, Robert Bals, Felix Beuschlein, Michael Böhm, Ulrich Büttner, Rainer Düsing, Fikret Er, Michael Fromm, Steffen Gay, Michael Geißler, Roland Gärtner, Michael Hallek, Sigrid Harendza, Ulrich Hoffmann, Reinhard Hohlfeld, Dieter Häussinger, Lothar Kanz, Stefan Kaufmann, Michael Kindermann, Jürgen Kohlhase, Karl-Anton Kreuzer, Ulrich Laufs, Andreas Link, Michael Ludwig, Christoph Maack, Stephan Martin, Darius Moradpour, Ulf Müller-Ladner, Peter P. Nawroth, Christoph Neumann-Haefelin, Wolfgang H. Oertel, Oliver G. Opitz, Rolf Ostendorf, Ulf Panzer, Eberhard Passarge, Hans-Hartmut Peter, Werner J. Pichler, Martin Reincke, Werner O. Richter, Felix Rosenow, Tom Schaberg, Bruno Scheller-Clever, Karsten Schepelmann, Werner A. Scherbaum, Andre Schneider, Jochen Schopohl, Henning Schwacha, Abdul Nasser Semmo, Konstanze Spieth, Rolf A.K. Stahl, Peter Staib, Eggert Stockfleth, Christian Strasburger, Federico Tató, Rudolf Tau

    Lingua: Tedesco

    Editore: Thieme Auflage: 9, völlig neu bearbeitete Auflage

    3134496097 / 9783134496093

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    Da: BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, GermaniaBUCHSERVICE / ANTIQUARIAT Lars Lutzer

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    Hardcover. Condizione: gut. Anschaulich und praxisnah - Die "große Pathophysiologie", das Nachschlagewerk für alle grundlegenden klinischen Fragestellungen - Die Brücke zur Klinik: Einbindung klinischer, diagnostischer und therapeutischer Aspekte - Ausführlich und klar strukturiert - Klare Gliederung, logische Kapitelstruktur: kurze Rekapitulation der physiologischen Grundlagen, allgemeine Pathophysiologie, spezielle Pathophysiologie - Verstehen und begreifen, statt stures Auswendiglernen: - Optimales Verständnis durch zahlreiche Abbildungen, Schemata, Tabellen und Synopsen Inhalt: Genetik Stoffwechsel Innere Sekretion Blut Immunsystem Infektion Kreislauf Lunge und Atmung Verdauung Niere und ableitende Harnwege Bewegungsapparat Nervensystem Neoplasien Indikation, Kontraindikation OP-Vorbereitung Spezielle Risiken und Aufklärung Lagerung etc. Atlasteil mit allen OP-Schritten in detaillierten Bildern mit ausführlichen Legenden Präzise Zeichnungen veranschaulichen das praktische Vorgehen Sprache deutsch Maße 1950 x 2700 mm Gewicht 3442 g Einbandart gebunden Mediziner Pharmazie Klinik und Praxis Allgemeinmediziner Studium Querschnittsbereiche ? Klinisch-pathologische Konferenz Hardcover Medizin Klinische Fächer HumanMedizin Klinikum medizinische Fächer Innere Medizin IntensivMedizin Allgemeinmedizin Pathophysiologie Studium Humanmediziner 2. Studienabschnitt Innere Medizin ISBN-10 3-13-449609-7 3134496097 ISBN-13 978-3-13-449609-3 9783134496093 Co-Autor Beatrice Amann-Vesti, Christian Arnold, Robert Bals, Felix Beuschlein, Michael Böhm, Ulrich Büttner, Rainer Düsing, Fikret Er, Michael Fromm, Steffen Gay, Michael Geißler, Roland Gärtner, Michael Hallek, Sigrid Harendza, Ulrich Hoffmann, Reinhard Hohlfeld, Dieter Häussinger, Lothar Kanz, Stefan Kaufmann, Michael Kindermann, Jürgen Kohlhase, Karl-Anton Kreuzer, Ulrich Laufs, Andreas Link, Michael Ludwig, Christoph Maack, Stephan Martin, Darius Moradpour, Ulf Müller-Ladner, Peter P. Nawroth, Christoph Neumann-Haefelin, Wolfgang H. Oertel, Oliver G. Opitz, Rolf Ostendorf, Ulf Panzer, Eberhard Passarge, Hans-Hartmut Peter, Werner J. Pichler, Martin Reincke, Werner O. Richter, Felix Rosenow, Tom Schaberg, Bruno Scheller-Clever, Karsten Schepelmann, Werner A. Scherbaum, Andre Schneider, Jochen Schopohl, Henning Schwacha, Abdul Nasser Semmo, Konstanze Spieth, Rolf A.K. Stahl, Peter Staib, Eggert Stockfleth, Christian Strasburger, Federico Tató, Rudolf Tauber, Friedrich Thaiss, Robert Thimme, Claus Franz Vogelmeier, Katja C. Weisel, Ulrich Wenzel, Walter Zidek, Reinhard Ziegler, Michael Zimmermann, Marek Zygmunt, Arnold von Eckardstein Sprache deutsch Maße 195 x 270 mm Gewicht 3442 g Klinische Pathophysiologie (Gebundene Ausgabe) von Walter Siegenthaler (Herausgeber), Hubert Erich Blum (Herausgeber) Stoffwechsel Innere Sekretion Blut Immunsystem Infektion Kreislauf Lunge Atmung Verdauung Niere ableitende Harnwege Bewegungsapparat Nervensystem Neoplasien Physiologie Krankheitsbilder Medizin In deutscher Sprache. 1232 pages. 27,6 x 20,4 x 6,6 cm Auflage: 9, völlig neu bearbeitete Auflage.…

  • Handbuch der Liturgik. Liturgiewissenschaft in Theologie und Praxis der Kirche: Liturgiewissenschaft in Theologie und Praxis der Kirche Religion Theologe Christentum Homiletik Evangelische Kirche Evangelische Theologie Gottesdienst Liturgie Liturgiewissenschaft Handbuch Lehrbuch Liturgie Liturgik Glauben Kirchen Glaube Hg.Schmidt-Lauber/Bieritz 3.A (Orbis Biblicus Et Orientalis) [Hardcover] Bieritz, Karl-Heinrich; Schmidt-Lauber, Hans-Christoph; Meyer-Blanck, Michael; Albrecht, Christoph; Berger, Teresa; Bloth, Peter C.; Bürki, Bruno; Daiber, Karl-Fritz; Enzner-Probst, Brigitte; Grethlein, Christian; Heinz, Andreas; Hofhansl, Ernst; Horn, Werner; Kirste, Reinhard; Körtner, Ulrich H.J.; Kornemann, Helmut; Kühn, Ulrich; Lührs, Walther; Raschzok, Klaus; Ratzmann, Wolfgang; Reich, Christa; Reich, Werner; Suhr, Ulrike; Vogel, Ingrid; Wainwright D.D., Geoffrey; Ziemer, Jürgen; Fischer, Balthasar; Bunners, Christian; Dahlgrün, Corinna; Dienst, Karl; Häußling, Angelus Albert; Hertzsch, Klaus-P

    Christoph Albrecht, Teresa Berger, Peter C. Bloth, Bruno Bürki, Karl-Fritz Daiber, Brigitte Enzner-Probst, Christian Grethlein, Andreas Heinz, Ernst Hofhansl, Werner Horn, Reinhard Kirste, Ulrich H.J. Körtner, Helmut Kornemann, Ulrich Kühn, Walther Lührs, Michael Meyer-Blanck, Klaus Raschzok, Wolfgang Ratzmann, Christa Reich, Werner Reich, Ulrike Suhr, Ingrid Vogel, D.D. Wainwright Geoffrey, Jürgen Ziemer, Balthasar Fischer, Christian Bunners, Corinna Dahlgrün, Karl Dienst, Angelus Albert Häußling, Klaus-Peter Hertzsch, Jens Langer, Friedemann Merkel, Jürgen Roloff, Frieder Schulz, Doris Winkel, Karl-Friedrich Wiggermann, Eberhard Winkler, Konrad Müller

    Lingua: Tedesco

    Editore: Vandenhoeck & Ruprecht Gmbh & Co, 2003

    3525572107 / 9783525572108

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    Da: BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, GermaniaBUCHSERVICE / ANTIQUARIAT Lars Lutzer

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    Hardcover. Condizione: gut. Umfassend überarbeitete Neuauflage des Standardwerks der evangelischen Liturgik unter besonderer Berücksichtigung der neuen Agendenwerke.This Compendium of Liturgics" has long been a tried and tested companion for both practical and theoretical theologians. In this the third edtion both the contents and the thematic breadth as well as the circle of authors have been expanded considerably. The result is a book that presents many new approaches to the subject. The editors have put particular emphasis on the creative leeway present in occasional services and the newer forms of church services, such as those now found in the new "Handbook of Protestant Services." The scope of this volume, however, is not limited to Protestantism but rather is ecumenical and international in nature.This handbook provides many references to modern literature on this theme including the relevant Internet addresses. A detailed index enables quick and targeted work.Anyone interested in the various forms of liturgy in the Christian churches will find here both basic and in-depth state-of-the-art information." Das »Handbuch der Liturgik« ist ein bewährter Begleiter im theologischen Alltag. Für diese dritte Auflage wurden Inhalt und thematisches Spektrum sowie der Kreis der Mitarbeiter erheblich erweitert. So ist ein Buch entstanden, das sich in Grundriss wie Ausführung neuen Möglichkeiten stellt. Besondere Aufmerksamkeit gilt dabei den Kasualgottesdiensten sowie den neuen Gottesdienstformen und Gestaltungsspielräumen, wie sie das »Evangelische Gottesdienstbuch« eröffnet. Dabei beschränkt sich das Handbuch konfessionell nicht auf die Protestanten, sondern ist ökumenisch und international ausgerichtet.Das neue »Handbuch« ist Lehr-, Studien- und Werkbuch in einem. Es wendet sich an Pfarrerinnen und Pfarrer, die nach Anregungen für ihre liturgische Praxis suchen, diese aber zugleich theologisch, anthropologisch sowie historisch begründen und reflektieren wollen. Studierenden der Theologie bietet es umfassende Informationen zum Gesamtfeld gottesdienstlicher Kultur. Historikern, Kultur- und Sozialwissenschaftlern wie Vertretern anderer Disziplinen kann es als zuverlässiges Nachschlagewerk dienen. Das Handbuch bietet Hinweise auf die aktuelle Literatur und nennt einschlägige Internet-Adressen. Ein umfangreiches Register ermöglicht zielgerichtetes Arbeiten. Wer immer sich für das gottesdienstliche Handeln der christlichen Kirchen interessiert, erhält hier grundlegende Informationen auf dem neuesten Stand der Wissenschaft. Co-Autor Christoph Albrecht, Teresa Berger, Peter C. Bloth, Bruno Bürki, Karl-Fritz Daiber, Brigitte Enzner-Probst, Christian Grethlein, Andreas Heinz, Ernst Hofhansl, Werner Horn, Reinhard Kirste, Ulrich H.J. Körtner, Helmut Kornemann, Ulrich Kühn, Walther Lührs, Michael Meyer-Blanck, Klaus Raschzok, Wolfgang Ratzmann, Christa Reich, Werner Reich, Ulrike Suhr, Ingrid Vogel, D.D. Wainwright Geoffrey, Jürgen Ziemer, Balthasar Fischer, Christian Bunners, Corinna Dahlgrün, Karl Dienst, Angelus Albert Häußling, Klaus-Peter Hertzsch, Jens Langer, Friedemann Merkel, Jürgen Roloff, Frieder Schulz, Doris Winkel, Karl-Friedrich Wiggermann, Eberhard Winkler, Konrad Müller Sprache deutsch Religion Theologie Christentum Homiletik Evangelische Kirche Evangelische Theologie Gottesdienst Liturgie Liturgiewissenschaft Handbuch Lehrbuch Liturgie Liturgik ISBN-10 3-525-57210-7 3525572107 ISBN-13 978-3-525-57210-8 9783525572108 In deutscher Sprache. 990 pages. 2003 | 3., vollständig neu bearb. und ergänzte Auflage 2003.…

  • Lingua: Inglese

    Editore: Springer Berlin Heidelberg, Springer Berlin Heidelberg Dez 1982, 1982

    3540117385 / 9783540117384

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    Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Peter A. Miescher The skin has always been one of the major targets to clinicians interested in immunology. Initially, the main focus was centred on allergic conditions such as contact hypersensitivity and urticeria. Gradually, the spectrum of immunological conditions involving the skin increased, encompassing diseases such as Dermatitis Herpetiformis, Erythema Muitiforme, Cutaneous Bullous Disorders and Photo toxic Reactions. It has been the intention of the editors of Springer Seminars in Immu nopathology to cover the broad spectrum of immune phenomena encountered in dermatological diseases with special emphasis to newer developments in Immunopathology. Dr. 1. N. Gigli has managed to assemble a series of important contributions within two issues of the Journal which are of such an interest to dermatologists that we decided to publish this topic as a separate volume for all dermatologists who do not have access to Seminars in Immunopathology. 3 Immunologically Mediated Epidermal Cell Injury Richard D. Sontheimer\* and James N. Gilliam Division of Dermatology, University of Texas Health Science Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235, USA Introduction The epidermis is a functional unit of different cell types that has the critical role of protecting man from his environment. The three major cell types that make up the epidermis (keratinocytes, melanocytes, and Langerhans cells) serve different protective functions. The vast majority of epidermal cells are keratinocytes (Fig. 1). 196 pp. Englisch.…

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    Editore: Springer Berlin Heidelberg, Springer Berlin Heidelberg Apr 1985, 1985

    3540150757 / 9783540150756

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    Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

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    Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Activation of the complement system gives rise to a number of molecular species which can interact with host-derived cells and regulate their function. This interaction is mediated through distinct cell surface complement receptors, and receptor engagement produces biologic responses which can either modulate host defense reactions or enhance inflammation. Although the first complement receptor was recognized more than 30 years ago [80J, detailed biochemical information concerning the receptors has only recently become available. Currently, eight distinct complement receptors are recognized. Five receptors (CRl, CR2, CR3, C3a receptor, and C3e receptor) react with various regions on C3 while the other receptors display specificity for Clq, C5a, or Factor H. This chapter focusses on the chemistry of the various ligands and receptors and discusses the biologic activities which arise as a result of receptor-ligand interaction. II. CIQ Receptor A. The Ligand Clq is the recognition molecule of the classical complement pathway [reviewed in 20, 130]. In serum, it is part of a calcium-dependent penta molecular complex containing one molecule ofClq and two molecules each of the pro enzymes Clr and CIs. During classical pathway activation, the macromolecular complex becomes associated with the activator through the Clq subcomponent. Bound Clq undergoes a conformational change and induces the proteolytic autoactivation of Clr which in turn effects the proteolytic activation of CIs. This process is controlled by the Cl inhibitor (ClINH) which binds irreversibly to activated Clr and CIs, and inhibits their enzymatic activities. 484 pp. Englisch.…

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    Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. and Overview.- Basic Aspects.- Structure and Expression of the C3 Gene.- Molecular Genetics of the Major Histocompatibility Linked Complement Genes.- The ?-Cys-?-Glu Thiolester Bond in Human C3 and C4, and ?2-Macroglobulin.- Structure and Function of the An.…

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    3540117385 / 9783540117384

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    Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Peter A. Miescher The skin has always been one of the major targets to clinicians interested in immunology. Initially, the main focus was centred on allergic conditions such as contact hypersensitivity and urticeria. Gradually, the spectrum of immunological.…

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    Taschenbuch. Condizione: Neu. Complement | P. A. Miescher (u. a.) | Taschenbuch | vi | Englisch | 1985 | Springer Vieweg | EAN 9783540150756 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand.…

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    Taschenbuch. Condizione: Neu. Immunodermatology | I. N. Gigli (u. a.) | Taschenbuch | vi | Englisch | 1982 | Springer | EAN 9783540117384 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand.…

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    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Activation of the complement system gives rise to a number of molecular species which can interact with host-derived cells and regulate their function. This interaction is mediated through distinct cell surface complement receptors, and receptor engagement produces biologic responses which can either modulate host defense reactions or enhance inflammation. Although the first complement receptor was recognized more than 30 years ago [80J, detailed biochemical information concerning the receptors has only recently become available. Currently, eight distinct complement receptors are recognized. Five receptors (CRl, CR2, CR3, C3a receptor, and C3e receptor) react with various regions on C3 while the other receptors display specificity for Clq, C5a, or Factor H. This chapter focusses on the chemistry of the various ligands and receptors and discusses the biologic activities which arise as a result of receptor-ligand interaction. II. CIQ Receptor A. The Ligand Clq is the recognition molecule of the classical complement pathway [reviewed in 20, 130]. In serum, it is part of a calcium-dependent penta molecular complex containing one molecule ofClq and two molecules each of the pro enzymes Clr and CIs. During classical pathway activation, the macromolecular complex becomes associated with the activator through the Clq subcomponent. Bound Clq undergoes a conformational change and induces the proteolytic autoactivation of Clr which in turn effects the proteolytic activation of CIs. This process is controlled by the Cl inhibitor (ClINH) which binds irreversibly to activated Clr and CIs, and inhibits their enzymatic activities.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 484 pp. Englisch.…

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    Editore: Springer Berlin Heidelberg, Springer Dez 1982, 1982

    3540117385 / 9783540117384

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    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Peter A. Miescher The skin has always been one of the major targets to clinicians interested in immunology. Initially, the main focus was centred on allergic conditions such as contact hypersensitivity and urticeria. Gradually, the spectrum of immunological conditions involving the skin increased, encompassing diseases such as Dermatitis Herpetiformis, Erythema Muitiforme, Cutaneous Bullous Disorders and Photo toxic Reactions. It has been the intention of the editors of Springer Seminars in Immu nopathology to cover the broad spectrum of immune phenomena encountered in dermatological diseases with special emphasis to newer developments in Immunopathology. Dr. 1. N. Gigli has managed to assemble a series of important contributions within two issues of the Journal which are of such an interest to dermatologists that we decided to publish this topic as a separate volume for all dermatologists who do not have access to Seminars in Immunopathology. 3 Immunologically Mediated Epidermal Cell Injury Richard D. Sontheimer\* and James N. Gilliam Division of Dermatology, University of Texas Health Science Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235, USA Introduction The epidermis is a functional unit of different cell types that has the critical role of protecting man from his environment. The three major cell types that make up the epidermis (keratinocytes, melanocytes, and Langerhans cells) serve different protective functions. The vast majority of epidermal cells are keratinocytes (Fig. 1).Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 196 pp. Englisch.…