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Aggiungi al carrelloTaschenbuch. Condizione: Neu. DNA Recognition with Dimeric Calixarenes | Towards Sequence-Selective DNA Recognition with Designed Major Groove Binders | Wenbin Hu | Taschenbuch | Englisch | 2015 | Scholars' Press | EAN 9783639761320 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
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Aggiungi al carrelloCondizione: New. Cheng Zhong is an associate professor in the School of Materials Science and Engineering at Tianjin University. Prior to joining the faculty at Tianjin University, he worked as an associate professor in the State Key Laboratory of Metal .
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Aggiungi al carrelloGebunden. Condizione: New. Cheng Zhong is an associate professor in the School of Materials Science and Engineering at Tianjin University. Prior to joining the faculty at Tianjin University, he worked as an associate professor in the State Key Laboratory of Metal .
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This work was performed during the period from August 2007 to April 2011 at the Department of Organic Chemistry, University of Duisburg-Essen, under the supervision of Prof. Dr. Thomas Schrader. Firstly, we synthezed a new class of calixarene dimers and elucidated their binding mechanism towards various nucleic acids. The results of multiple established DNA binding assays provided experimental evidence for noncovalent major groove recognition. Secondly, we replaced the simple alkyl bridge between both calixarenes by a triimidazole bridge. The triimidazole bridge was able to recognize the base sequence, and we found that this dimer showed the strongest affinity for a predicted DNA sequence. We believed that our work paved the way to sequence-selective DNA recognition inside the major groove. 292 pp. Englisch.
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Aggiungi al carrelloCondizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Hu Wenbin1999-2003 B.S. in Pharmaceutical Science, Peking University, P. R. China. 2005-2007 M.S. in Chemistry, Uppsala Universitet, Sweden. 2007-2011 Ph.D. (Dr. rer. nat.) in Chemistry, Universitaet Duisburg-Essen, Germany.This w.
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This work was performed during the period from August 2007 to April 2011 at the Department of Organic Chemistry, University of Duisburg-Essen, under the supervision of Prof. Dr. Thomas Schrader. Firstly, we synthezed a new class of calixarene dimers and elucidated their binding mechanism towards various nucleic acids. The results of multiple established DNA binding assays provided experimental evidence for noncovalent major groove recognition. Secondly, we replaced the simple alkyl bridge between both calixarenes by a triimidazole bridge. The triimidazole bridge was able to recognize the base sequence, and we found that this dimer showed the strongest affinity for a predicted DNA sequence. We believed that our work paved the way to sequence-selective DNA recognition inside the major groove.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 292 pp. Englisch.
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This work was performed during the period from August 2007 to April 2011 at the Department of Organic Chemistry, University of Duisburg-Essen, under the supervision of Prof. Dr. Thomas Schrader. Firstly, we synthezed a new class of calixarene dimers and elucidated their binding mechanism towards various nucleic acids. The results of multiple established DNA binding assays provided experimental evidence for noncovalent major groove recognition. Secondly, we replaced the simple alkyl bridge between both calixarenes by a triimidazole bridge. The triimidazole bridge was able to recognize the base sequence, and we found that this dimer showed the strongest affinity for a predicted DNA sequence. We believed that our work paved the way to sequence-selective DNA recognition inside the major groove.
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Aggiungi al carrelloCondizione: New. PRINT ON DEMAND pp. 292.