jaiswal manoj kumar (27 risultati)

Taschenbuch. Condizione: Neu. Mitochondrial signaling and Ca2+ dysregulation in motorneurons | Implications for the selective vulnerability in amyotrophic lateral sclerosis (ALS) | Manoj Kumar Jaiswal | Taschenbuch | 180 S. | Englisch | 2012 | LAP LAMBERT Academic Publishing | EAN 9783848449699 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Condizione: New. pp. 270.

Condizione: New. pp. 270.

Paperback. Condizione: Brand New. 300 pages. 9.00x6.00x0.59 inches. In Stock.

Paperback / softback. Condizione: New. New copy - Usually dispatched within 4 working days.

Condizione: New. pp. 270.

Paperback. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Taschenbuch. Condizione: Neu. Tdp-43 and Neurodegeneration | From Bench to Bedside | Vijay Kumar (u. a.) | Taschenbuch | Englisch | 2021 | Elsevier Science | EAN 9780128200667 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu.

Condizione: New.

Paperback. Condizione: new. Paperback. This book presents the select proceedings of the 9th National Conference on Advances in Metrology (AdMet 2024). It highlights and discusses the recent technological advancements and developments in the areas of fundamental and quantum metrology, physico-mechanical and electrical metrology, time and frequency metrology, materials metrology, industrial and legal metrology, and digital metrology, gas and aerosol metrology among others. This book is aimed at those engaged in conformity assessment, quality system management, calibration, and testing in all sectors of industry as well as in academic research. The book is a valuable reference for metrologists, scientists, engineers, academicians, and students from research institutes and industrial establishments to explore future directions and research in the areas of sensors, advanced materials, measurements, and quality improvement. It highlights and discusses the recent technological advancements and developments in the areas of fundamental and quantum metrology, physico-mechanical and electrical metrology, time and frequency metrology, materials metrology, industrial and legal metrology, and digital metrology, gas and aerosol metrology among others. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

Condizione: As New. Unread book in perfect condition.

Taschenbuch. Condizione: Neu. Advances in Metrology | Select Proceedings of AdMet 2024 | Sanjay Yadav (u. a.) | Taschenbuch | Lecture Notes in Mechanical Engineering | xi | Englisch | 2025 | Springer | EAN 9789819664177 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Condizione: New.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book presents the select proceedings of the 9th National Conference on Advances in Metrology (AdMet 2024). It highlights and discusses the recent technological advancements and developments in the areas of fundamental and quantum metrology, physico-mechanical and electrical metrology, time and frequency metrology, materials metrology, industrial and legal metrology, and digital metrology, gas and aerosol metrology among others. This book is aimed at those engaged in conformity assessment, quality system management, calibration, and testing in all sectors of industry as well as in academic research. The book is a valuable reference for metrologists, scientists, engineers, academicians, and students from research institutes and industrial establishments to explore future directions and research in the areas of sensors, advanced materials, measurements, and quality improvement.

Paperback. Condizione: Brand New. 285 pages. 9.26x6.11x9.25 inches. In Stock.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective death of subsets of motorneuorn (MN) populations in the brainstem and spinal cord with signature hallmarks of mitochondrial Ca2+ overload, homeostasis dysregulation, excitotoxicity, impaired axonal transport, muscle weakness and paralysis. Although disruptions of cytosolic and mitochondrial Ca2+ (in particular low ([Ca2+]i) buffering and a strong interaction between metabolic mechanisms and [Ca2+]i) have been associated with selective motoneuron degeneration, the underlying mechanisms are not well understood. The present evidence supports a hypothesis that mitochondria are a primary target of SOD1-mediated toxicity in ALS, and intracellular alterations of cytosolic and mitochondria-ER microdomain calcium accumulation might aggravate the course of this neurodegenerative disease. This book aims to provide an overview of the known players and their interactions, their role in the selective MN loss, recent advances in this field and a detailed discussion about what has been learned about Ca2+ homeostasis and the role of mitochondria in MNs in pathophysiological conditions. 180 pp. Englisch.

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Jaiswal Manoj KumarManoj Jaiswal, received his PhD in neuroscience from University of Goettingen, Germany (2007), followed by postdoctoral fellowship in neuronal engineering & circuitry at MIT in Boston, USA. Currently he is a resear.

Condizione: new. Questo è un articolo print on demand.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective death of subsets of motorneuorn (MN) populations in the brainstem and spinal cord with signature hallmarks of mitochondrial Ca2+ overload, homeostasis dysregulation, excitotoxicity, impaired axonal transport, muscle weakness and paralysis. Although disruptions of cytosolic and mitochondrial Ca2+ (in particular low ([Ca2+]i) buffering and a strong interaction between metabolic mechanisms and [Ca2+]i) have been associated with selective motoneuron degeneration, the underlying mechanisms are not well understood. The present evidence supports a hypothesis that mitochondria are a primary target of SOD1-mediated toxicity in ALS, and intracellular alterations of cytosolic and mitochondria-ER microdomain calcium accumulation might aggravate the course of this neurodegenerative disease. This book aims to provide an overview of the known players and their interactions, their role in the selective MN loss, recent advances in this field and a detailed discussion about what has been learned about Ca2+ homeostasis and the role of mitochondria in MNs in pathophysiological conditions.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 180 pp. Englisch.

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the selective death of subsets of motorneuorn (MN) populations in the brainstem and spinal cord with signature hallmarks of mitochondrial Ca2+ overload, homeostasis dysregulation, excitotoxicity, impaired axonal transport, muscle weakness and paralysis. Although disruptions of cytosolic and mitochondrial Ca2+ (in particular low ([Ca2+]i) buffering and a strong interaction between metabolic mechanisms and [Ca2+]i) have been associated with selective motoneuron degeneration, the underlying mechanisms are not well understood. The present evidence supports a hypothesis that mitochondria are a primary target of SOD1-mediated toxicity in ALS, and intracellular alterations of cytosolic and mitochondria-ER microdomain calcium accumulation might aggravate the course of this neurodegenerative disease. This book aims to provide an overview of the known players and their interactions, their role in the selective MN loss, recent advances in this field and a detailed discussion about what has been learned about Ca2+ homeostasis and the role of mitochondria in MNs in pathophysiological conditions.

Condizione: new. Questo è un articolo print on demand.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. 270 pp. Englisch.

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43's structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents the select proceedings of the 9th National Conference on Advances in Metrology (AdMet 2024). It highlights and discusses the recent technological advancements and developments in the areas of fundamental and quantum metrology, physico-mechanical and electrical metrology, time and frequency metrology, materials metrology, industrial and legal metrology, and digital metrology, gas and aerosol metrology among others. This book is aimed at those engaged in conformity assessment, quality system management, calibration, and testing in all sectors of industry as well as in academic research. The book is a valuable reference for metrologists, scientists, engineers, academicians, and students from research institutes and industrial establishments to explore future directions and research in the areas of sensors, advanced materials, measurements, and quality improvement. 274 pp. Englisch.

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book presents the select proceedings of the 9th National Conference on Advances in Metrology (AdMet 2024). It highlights and discusses the recent technological advancements and developments in the areas of fundamental and quantum metrology, physico-mechanical and electrical metrology, time and frequency metrology, materials metrology, industrial and legal metrology, and digital metrology, gas and aerosol metrology among others. This book is aimed at those engaged in conformity assessment, quality system management, calibration, and testing in all sectors of industry as well as in academic research. The book is a valuable reference for metrologists, scientists, engineers, academicians, and students from research institutes and industrial establishments to explore future directions and research in the areas of sensors, advanced materials, measurements, and quality improvement.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 288 pp. Englisch.

Condizione: New. Print on Demand.

Condizione: New. PRINT ON DEMAND.