jan hradec (8 risultati)

Condizione: New. In.

Condizione: New. pp. 280.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - The hepatocarcinogenicity of aflatoxin BI in rats, ducks and rainbow trout has been convincingly demonstrated (1). In contrast, adult mice appear to be resistant to the toxic and carcinogenic effects. Newborn and infant mice are more sensitive to the effects of different hepatocarcinogens (2,3) and also to AFB , which induced hepatomas in newborn C57BL/6 x C3H FI I mice (4). A singl~ dose model of aflatoxin hepatocarcinogenesis was tested in infant C57BL/6 mice. AFBI was administered i.p. on day 7 after birth and the following data were investigated: 1) Changes in the activities of microsomal cytochrome P-450 dependant enzymes and conjugating enzymes in the course of the 20-month-Iong aflatoxin hepa tocarcinogenesis study. At intervals of 6,8,12,18 and 20 months a~ter AFBI administration, the concentrations of cyt P-450 andb and the acti 5 vities of NADPH-, NADH-cyt c reductase, AOH, ADM, EH and GST were deter mined. 2) Effect of continually administered diethyldithiocarbamate on the course of aflatoxin carcinogenesis. MATERIALS AND METHODS Aflatoxin BI was prepared biosynthetically in our laboratory and was checked for purity chromatographically, spectrophotometrically and by NMR.

Hardcover. Condizione: Good. Good. Dust Jacket NOT present. CD WILL BE MISSING. . SHIPS FROM MULTIPLE LOCATIONS. book.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The hepatocarcinogenicity of aflatoxin BI in rats, ducks and rainbow trout has been convincingly demonstrated (1). In contrast, adult mice appear to be resistant to the toxic and carcinogenic effects. Newborn and infant mice are more sensitive to the effects of different hepatocarcinogens (2,3) and also to AFB , which induced hepatomas in newborn C57BL/6 x C3H FI I mice (4). A singl~ dose model of aflatoxin hepatocarcinogenesis was tested in infant C57BL/6 mice. AFBI was administered i.p. on day 7 after birth and the following data were investigated: 1) Changes in the activities of microsomal cytochrome P-450 dependant enzymes and conjugating enzymes in the course of the 20-month-Iong aflatoxin hepa tocarcinogenesis study. At intervals of 6,8,12,18 and 20 months a~ter AFBI administration, the concentrations of cyt P-450 andb and the acti 5 vities of NADPH-, NADH-cyt c reductase, AOH, ADM, EH and GST were deter mined. 2) Effect of continually administered diethyldithiocarbamate on the course of aflatoxin carcinogenesis. MATERIALS AND METHODS Aflatoxin BI was prepared biosynthetically in our laboratory and was checked for purity chromatographically, spectrophotometrically and by NMR. 280 pp. Englisch.

Condizione: New. Print on Demand pp. 280 67:B&W 6.69 x 9.61 in or 244 x 170 mm (Pinched Crown) Perfect Bound on White w/Gloss Lam.

Condizione: New. PRINT ON DEMAND pp. 280.

Kartoniert / Broschiert. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Chemical Carcinogenesis and the Primary Prevention of Human Cancer.- Metabolism of Chemical Carcinogens.- Mechanisms of Chemical Carcinogenesis.- Chemical Carcinogens Present in Nigerian (African) Foods and Drinks.- Conversion Induced by Transforming Growth.