Jyoshna rani dash (75 risultati)

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Taschenbuch. Condizione: Neu. Determination of some Isoflavonoids against mammary cell carcinoma | To evaluate the anti-cancer activity of Limonia acidissima L. used traditionally for various malignant diseases | Jyoshna Rani Dash (u. a.) | Taschenbuch | Englisch | 2020 | LAP LAMBERT Academic Publishing | EAN 9786203029383 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Taschenbuch. Condizione: Neu. Biopharmaceutics of Ocular Drug Delivery Systems | Drug delivery to targeted ocular tissues has been a major challenge to ocular scientists for decades | Jyoshna Rani Dash (u. a.) | Taschenbuch | Englisch | 2020 | LAP LAMBERT Academic Publishing | EAN 9786203197945 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -To evaluate the anti-cancer activity of Limonia acidissima Linn (Rutaceae) which has long been used traditionally for various infectious and malignant diseases. The fruit extract of Limonia acidissima Linn was obtained by macerating 3 times with methanol and then concentrating it at reduced pressure. Bioassay of the extract was carried out to assess the anticancer activity. Breast cancer cell lines, SKBR3 and MDA MB435, were used for in-vitro cell proliferation, cell viability assay, and cell cycle analysis of the extract.Results: Bioassay of the extract of Limonia acidissima Linn. showed that a fraction (fraction 3) of the ethanol extract had anticancer activity against SKBR3 and MDA-MB435 human breast cancer cells. The effective dose (ED50) of Limonia acidissima Linn. fraction 3 was 56.1 and 30.6 mig/ml for SKBR3 and MDA-MB435, respectively. After 48 h of exposure, this fraction (100 mig/ml) significantly reduced cell proliferation in both cancer cell lines. In MDA-MB435 cells, cell cycle analysis showed that fraction 3induced the accumulation of cells in G2/M phase, but no significant change in cell cycle was detected in SKBR3 cells. 64 pp. Englisch.…

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Evaluar la actividad anticancerosa de la Limonia acidissima Linn (Rutáceas), que se ha utilizado tradicionalmente durante mucho tiempo para diversas enfermedades infecciosas y malignas. El extracto de la fruta de Limonia acidissima Linn se obtuvo mediante la maceración de 3 veces con metanol y luego concentrándolo a presión reducida. Se realizó un bioensayo del extracto para evaluar la actividad anticancerígena. Las líneas celulares de cáncer de mama, SKBR3 y MDA MB435, se utilizaron para la proliferación celular in vitro, el ensayo de viabilidad celular y el análisis del ciclo celular del extracto. Resultados: El bioensayo del extracto de Limonia acidissima Linn. mostró que una fracción (fracción 3) del extracto de etanol tenía actividad anticancerígena contra las células de cáncer de mama humano SKBR3 y MDA-MB435. La dosis efectiva (ED50) de la fracción 3 de Limonia acidissima Linn. fue de 56,1 y 30,6 ¿g/ml para SKBR3 y MDA-MB435, respectivamente. Después de 48 h de exposición, esta fracción (100 ¿g/ml) redujo significativamente la proliferación celular en ambas líneas celulares de cáncer. En las células MDA-MB435, el análisis del ciclo celular mostró que la fracción 3inducía la acumulación de células en la fase G2/M, pero no se detectó ningún cambio significativo en el ciclo celular en las células SKBR3. 76 pp. Spanisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - To evaluate the anti-cancer activity of Limonia acidissima Linn (Rutaceae) which has long been used traditionally for various infectious and malignant diseases. The fruit extract of Limonia acidissima Linn was obtained by macerating 3 times with methanol and then concentrating it at reduced pressure. Bioassay of the extract was carried out to assess the anticancer activity. Breast cancer cell lines, SKBR3 and MDA MB435, were used for in-vitro cell proliferation, cell viability assay, and cell cycle analysis of the extract.Results: Bioassay of the extract of Limonia acidissima Linn. showed that a fraction (fraction 3) of the ethanol extract had anticancer activity against SKBR3 and MDA-MB435 human breast cancer cells. The effective dose (ED50) of Limonia acidissima Linn. fraction 3 was 56.1 and 30.6 mig/ml for SKBR3 and MDA-MB435, respectively. After 48 h of exposure, this fraction (100 mig/ml) significantly reduced cell proliferation in both cancer cell lines. In MDA-MB435 cells, cell cycle analysis showed that fraction 3induced the accumulation of cells in G2/M phase, but no significant change in cell cycle was detected in SKBR3 cells.…

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The eye is a unique organ from an anatomical & physiological point of view. Without the eye, we cannot enjoy the beauty of nature. The eye is a highly specialized organ of photoreception for processing light energy from the environment to produce action potentials in specialized nerve cells, which subsequently relayed to the optic nerve and then to the brain where the information is processed and consciously appreciated as vision. The human eye can be generally divided into the anterior and the posterior segments. The anterior segment includes the cornea, conjunctiva, iris, ciliary body, aqueous humor and lens while the posterior segment comprises sclera, choroid, retina and vitreous humor. The eyeball is an organ protected from exogenous substances and external stress by various barriers, therefore, therapeutic drugs must be transported across several protective barriers regardless of which route administration utilized. The mechanism of ocular drug absorption can be influenced by physiological factors, physicochemical factors & dosage form factors. Physiologically corneal & non corneal drug absorption mechanisms are considered. 104 pp. Englisch.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Dash Jyoshna RaniMs. Jyoshna Rani Dash, M.pharm is working as a research scholar at the School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar, Odisha.To evaluate the anti-cancer acti.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The eye is a unique organ from an anatomical & physiological point of view. Without the eye, we cannot enjoy the beauty of nature. The eye is a highly specialized organ of photoreception for processing light energy from the environment to produce action potentials in specialized nerve cells, which subsequently relayed to the optic nerve and then to the brain where the information is processed and consciously appreciated as vision. The human eye can be generally divided into the anterior and the posterior segments. The anterior segment includes the cornea, conjunctiva, iris, ciliary body, aqueous humor and lens while the posterior segment comprises sclera, choroid, retina and vitreous humor. The eyeball is an organ protected from exogenous substances and external stress by various barriers, therefore, therapeutic drugs must be transported across several protective barriers regardless of which route administration utilized. The mechanism of ocular drug absorption can be influenced by physiological factors, physicochemical factors & dosage form factors. Physiologically corneal & non corneal drug absorption mechanisms are considered.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Évaluer l'activité anticancéreuse du Limonia acidissima Linn (Rutaceae) qui a longtemps été utilisé traditionnellement pour diverses maladies infectieuses et malignes. L'extrait de fruit de Limonia acidissima Linn a été obtenu par macération à 3 reprises avec du méthanol, puis par concentration à pression réduite. Un essai biologique de l'extrait a été effectué pour évaluer l'activité anticancéreuse. Des lignées cellulaires de cancer du sein, SKBR3 et MDA MB435, ont été utilisées pour la prolifération cellulaire in vitro, le test de viabilité cellulaire et l'analyse du cycle cellulaire de l'extrait : Le dosage biologique de l'extrait de Limonia acidissima Linn. a montré qu'une fraction (fraction 3) de l'extrait d'éthanol avait une activité anticancéreuse contre les cellules humaines SKBR3 et MDA-MB435 du cancer du sein. La dose efficace (ED50) de la fraction 3 de Limonia acidissima Linn. était de 56,1 et 30,6 mig/ml pour SKBR3 et MDA-MB435, respectivement. Après 48 heures d'exposition, cette fraction (100 mig/ml) a réduit de manière significative la prolifération cellulaire dans les deux lignées de cellules cancéreuses. Dans les cellules MDA-MB435, l'analyse du cycle cellulaire a montré que la fraction 3 induisait l'accumulation de cellules en phase G2/M, mais aucun changement significatif du cycle cellulaire n'a été détecté dans les cellules SKBR3. 80 pp. Französisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Evaluar la actividad anticancerosa de la Limonia acidissima Linn (Rutáceas), que se ha utilizado tradicionalmente durante mucho tiempo para diversas enfermedades infecciosas y malignas. El extracto de la fruta de Limonia acidissima Linn se obtuvo mediante la maceración de 3 veces con metanol y luego concentrándolo a presión reducida. Se realizó un bioensayo del extracto para evaluar la actividad anticancerígena. Las líneas celulares de cáncer de mama, SKBR3 y MDA MB435, se utilizaron para la proliferación celular in vitro, el ensayo de viabilidad celular y el análisis del ciclo celular del extracto. Resultados: El bioensayo del extracto de Limonia acidissima Linn. mostró que una fracción (fracción 3) del extracto de etanol tenía actividad anticancerígena contra las células de cáncer de mama humano SKBR3 y MDA-MB435. La dosis efectiva (ED50) de la fracción 3 de Limonia acidissima Linn. fue de 56,1 y 30,6 ¿g/ml para SKBR3 y MDA-MB435, respectivamente. Después de 48 h de exposición, esta fracción (100 ¿g/ml) redujo significativamente la proliferación celular en ambas líneas celulares de cáncer. En las células MDA-MB435, el análisis del ciclo celular mostró que la fracción 3inducía la acumulación de células en la fase G2/M, pero no se detectó ningún cambio significativo en el ciclo celular en las células SKBR3.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Dash Jyoshna RaniI am Jyoshna Rani Dash, working as an assistant professor at Centurion University of Technology and Management, Bhubaneswar. Area of interest is cancer research and diabetes.The eye is a unique organ from an anat.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -El ojo es un órgano único desde el punto de vista anatómico y fisiológico. Sin el ojo, no podemos disfrutar de la belleza de la naturaleza. El ojo es un órgano altamente especializado en la fotorrecepción para procesar la energía luminosa del entorno y producir potenciales de acción en células nerviosas especializadas, que posteriormente se transmiten al nervio óptico y luego al cerebro, donde la información se procesa y se aprecia conscientemente como visión. El ojo humano puede dividirse generalmente en los segmentos anterior y posterior. El segmento anterior incluye la córnea, la conjuntiva, el iris, el cuerpo ciliar, el humor acuoso y el cristalino, mientras que el segmento posterior comprende la esclerótica, la coroides, la retina y el humor vítreo. El globo ocular es un órgano protegido de las sustancias exógenas y del estrés externo por varias barreras, por lo que los fármacos terapéuticos deben ser transportados a través de varias barreras protectoras, independientemente de la vía de administración utilizada. El mecanismo de absorción ocular de los fármacos puede verse influido por factores fisiológicos, fisicoquímicos y de forma de dosificación. Se consideran los mecanismos fisiológicos de absorción de fármacos corneales y no corneales. 112 pp. Spanisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -To evaluate the anti-cancer activity of Limonia acidissima Linn (Rutaceae) which has long been used traditionally for various infectious and malignant diseases. The fruit extract of Limonia acidissima Linn was obtained by macerating 3 times with methanol and then concentrating it at reduced pressure. Bioassay of the extract was carried out to assess the anticancer activity. Breast cancer cell lines, SKBR3 and MDA MB435, were used for in-vitro cell proliferation, cell viability assay, and cell cycle analysis of the extract.Results: Bioassay of the extract of Limonia acidissima Linn. showed that a fraction (fraction 3) of the ethanol extract had anticancer activity against SKBR3 and MDA-MB435 human breast cancer cells. The effective dose (ED50) of Limonia acidissima Linn. fraction 3 was 56.1 and 30.6 ¿g/ml for SKBR3 and MDA-MB435, respectively. After 48 h of exposure, this fraction (100 ¿g/ml) significantly reduced cell proliferation in both cancer cell lines. In MDA-MB435 cells, cell cycle analysis showed that fraction 3induced the accumulation of cells in G2/M phase, but no significant change in cell cycle was detected in SKBR3 cells.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 64 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The eye is a unique organ from an anatomical & physiological point of view. Without the eye, we cannot enjoy the beauty of nature. The eye is a highly specialized organ of photoreception for processing light energy from the environment to produce action potentials in specialized nerve cells, which subsequently relayed to the optic nerve and then to the brain where the information is processed and consciously appreciated as vision. The human eye can be generally divided into the anterior and the posterior segments. The anterior segment includes the cornea, conjunctiva, iris, ciliary body, aqueous humor and lens while the posterior segment comprises sclera, choroid, retina and vitreous humor. The eyeball is an organ protected from exogenous substances and external stress by various barriers, therefore, therapeutic drugs must be transported across several protective barriers regardless of which route administration utilized. The mechanism of ocular drug absorption can be influenced by physiological factors, physicochemical factors & dosage form factors. Physiologically corneal & non corneal drug absorption mechanisms are considered.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 104 pp. Englisch.…