Kenneth a jacobson (28 risultati)

Hardcover. Condizione: As New. Like New, very light shelf wear.

Hardcover. Condizione: Fine. 1st Edition. Springer-Verlag pictorial hardcover, 1990, unused, No remainder marks or "shelf wear" (as New). We will bubble wrap the book and ship it in a New BOX- Not a plastic bag like the zombie sellers.

Hardcover. Condizione: Near Fine. No Jacket. 0387972447. Laminated Pictorial board, Unread, ex library hardcover, with minimal wear. 448 pages, index, illustrated with charts, tables and diagrams. The chemistry of purines and their receptors under headings: Adenosine Receptors and Effector Systems; Adenine Nucleotide Receptors and Effector Systems; Phosphodiesterase Enzymes and Inhibitors Presentations focus on development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Xanthines (caffeine and theophylline). Contents as new, clean, tight and bright. Unread. Book. …

Paperback. Condizione: Brand New. 1st edition. 309 pages. 8.75x6.00x1.00 inches. In Stock.

Spiral-bound. Condizione: Brand New. second edition edition. 314 pages. 9.00x6.00x0.71 inches. In Stock. Kelsey, Claudia; Jacobson, Terry; Britton, NL; Brown, A; Pearse, C. Kenneth (illustratore).

Condizione: very_good. Book has little sign of wear or use. Kelsey, Claudia; Jacobson, Terry; Britton, NL; Brown, A; Pearse, C. Kenneth (illustratore).

Condizione: New. In.

Paperback. Condizione: Brand New. reprint edition. 463 pages. 9.25x6.10x1.10 inches. In Stock.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Research on purine derivatives as potent and selective modulators of physiologic functions has moved to center stage. This volume covers the biology and chemistry of purines and of their receptors broadly under these section headings: - Adenosine Receptors and Effector Systems - Adenine Nucleotide Receptors and Effector Systems - Phosphodiesterase Enzymes and Inhibitors The presentations focus on the potential development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Xanthines (caffeine and theophylline) represent one class of such agents. This volume is for pharmacologists, biochemists, and medical chemists in research labs of universities, gov- ernment, and the pharmaceutical industry.…

Condizione: new.

Condizione: New.

Condizione: As New. Unread book in perfect condition.

Condizione: New.

Condizione: New. In English.

Condizione: As New. Unread book in perfect condition.

Condizione: New.

Gebunden. Condizione: New. Aiming to cover the major therapeutic applications of purinergic receptors and reflect the very latest developments in this area of therapeutic research, this book is authored by an international group of contributors who are authorities in the field.

Condizione: New. Aiming to cover the major therapeutic applications of purinergic receptors and reflect the very latest developments in this area of therapeutic research, this book is authored by an international group of contributors who are authorities in the field. Editor(s): Jacobson, Kenneth A.; Jarvis, Michael F. Num Pages: 582 pages, Illustrations. BIC Classification: MF; MMG; MMZ; PSD. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 223 x 169 x 34. Weight in Grams: 1038. . 1997. 1st Edition. Hardcover. . . . .…

Hardcover. Condizione: Brand New. 1st edition. 581 pages. 9.75x6.50x1.25 inches. In Stock.

Buch. Condizione: Neu. Neuware - International renommierte Autoren bringen Ihnen alle wichtigen therapeutischen Anwendungen purinerger Rezeptoren nahe und stellen die aktuellsten Entwicklungen dieses relativ jungen Forschungsgebietes dar. Neben Details zur molekularen Pharmakologie und medizinischen Chemie finden Sie Beiträge zu therapeutischen Implikationen in Kardiologie, Stoffwechsel, Immunologie, Neurologie und Krebstherapie.…

Condizione: New. Aiming to cover the major therapeutic applications of purinergic receptors and reflect the very latest developments in this area of therapeutic research, this book is authored by an international group of contributors who are authorities in the field. Editor(s): Jacobson, Kenneth A.; Jarvis, Michael F. Num Pages: 582 pages, Illustrations. BIC Classification: MF; MMG; MMZ; PSD. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 223 x 169 x 34. Weight in Grams: 1038. . 1997. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland.…

Condizione: new. Questo è un articolo print on demand.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research on purine derivatives as potent and selective modulators of physiologic functions has moved to center stage. This volume covers the biology and chemistry of purines and of their receptors broadly under these section headings: - Adenosine Receptors and Effector Systems - Adenine Nucleotide Receptors and Effector Systems - Phosphodiesterase Enzymes and Inhibitors The presentations focus on the potential development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Xanthines (caffeine and theophylline) represent one class of such agents. This volume is for pharmacologists, biochemists, and medical chemists in research labs of universities, gov- ernment, and the pharmaceutical industry. 468 pp. Englisch.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Section 1: Adenosine Receptors and Effector Systems.- 1 Adenosine Agonists and Antagonists.- 2 Intracellular and Extracellular Metabolism of Adenosine and Adenine Nucleotides.- 3 Adenosine Deaminase and Adenosine Transport Systems in the CNS.- 4 Transport S.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Section 1: Adenosine Receptors and Effector Systems.- 1 Adenosine Agonists and Antagonists.- 2 Intracellular and Extracellular Metabolism of Adenosine and Adenine Nucleotides.- 3 Adenosine Deaminase and Adenosine Transport Systems in the CNS.- 4 Transport Systems for Adenosine in Mammalian Cell Membranes.- 5 Formation of Adenosine in the Heart from Extracellular Adenine Nucleotides.- 6 Central Nervous System Effects of Adenosine.- 7 Adenosine Receptor Sub-types in Isolated Tissues: Antagonist Studies.- 8 Molecular Probes for Adenosine Receptors.- 9 Purification of A1 Adenosine Receptor of Rat Brain Membranes by Affinity Chromatography.- 10 Characteristics of A1 Adenosine Receptors and Guanine Nucleotide Binding Proteins Co-Purified from Bovine Brain.- 11 Antagonist Radioligand Binding to Solubilized Porcine Atrial A1 Adenosine Receptors.- 12 Isolation of an Adenosine Binding Protein Which Has Properties Expected of the A1 Adenosine Receptor.- 13 Identification of the A2 Adenosine Receptor Binding Subunit by Photoaffinity Crosslinking.- 14 Human Placental Adenosine A2-Like Binding Sites Properties and Homology with Mammalian and Avian Stress Proteins.- 15 Cardiac Interstitial Fluid Adenosine in Normoxia and Hypoxia.- 16 Rationale for the Use of Adenosine in the Diagnosis and Treatment of Cardiac Arrhythmias.- 17 The Central Adenosine System as a Therapeutic Target in Stroke.- 18 Adenosine-Mediated Vasoconstriction in the Skin Microcirculation.- 19 Adenosine is an Antiinflammatory Autocoid: Adenosine Receptor Occupancy Promotes Neutrophil Chemotaxis and Inhibits Superoxide Anion Generation.- 20 Beta Adrenergic Receptor Mediated Stimulation of Adenine Nucleotide Catabolism and Purine Release in Human Adipocytes.- 21 Structure Activity Relationships for Adenosine Antagonists.- 22 Structure Activity Relationships for Adenosine Agonists.- 23 The Design of a Series of Highly A2 Selective Adenosine Agonists.- 24 Adenosine Agonists. Characterization of the N6-Subregion of the Adenosine A2 Receptor via Molecular Modeling Techniques.- 25 Physiological and Biochemical Aspects of 'P'-Site-Mediated Inhibition of Adenylyl Cyclase.- 26 Adenosine Receptors Mediating Inhibition of Peripheral and Central Neurons.- 27 Adenosine Receptors as Drug Targets: Fulfilling the Promise .- 28 Mechanisms of Adenosine Action.- 29 Functional Roles of A1 and A2 Receptors in Rat Hippocampus and Striatum.- 30 Subclassification of Neuronal Adenosine Receptors.- 31 Effects of Adenosine on Mast Cells.- 32 The Role of Adenosine on the Gastric Acid Secretory Response.- 33 Adenosine Receptors and Signaling in the Kidney.- 34 Inhibition of the Function of Guanine Nucleotide Binding Proteins by the New Positive Inotropes.- 35 Blockade of Antigen Activated Signals by Xanthine Analogs in RBL-2H3 Cells:Evidence for a Novel Adenosine Receptor.- Section 2: Adenine Nucleotide Receptors and Effector Systems.- 36 Classification and Characterization of Purinoceptors.- 37 Structure Activity Relationships for Adenine Nucleotide Receptors on Mast Cells, Human Platelets, and Smooth Muscle.- 38 Modulation of Norepinephrine Release by ATP and Adenosine.- 39 The Phospholipase C Linked P2y-Purinergic Receptor.- 40 Roles of an ADP Receptor on the Platelet Surface in Mediating Aggregation and Fibrinogen Binding.- Section 3: Phosphodiesterase Enzymes and Inhibitors.- 41 Structural and Functional Characterization of Cyclic GMP-Stimulated Phosphodiesterases and Their Role in Intracellular Signal Transduction.- 42 Phosphodiesterase Genes from Flies to Mammals.- 43 Structure and Function of theHigh Affinity, Rolipram and RO 2-1724 Sensitive, cAMP Phosphodiesterases.- 44 Correlation of 3H-Rolipram Binding to a Cerebral cAMP Phosphodiesterase with Antidepressant Activity.- 45 Mechanism for Dual Regulation of the Particulate cGMP-Inhibited cAMP Phosphodiesterase in Rat Adipocytes by Isoproterenol and Insulin.- 46 Expression of Calmo.…

Hardcover. Condizione: new. Hardcover. Edited by Kenneth A. Jacobson and Michael F. Jarvis The roles of extracellular purines and pyrimidines in cellularhomeostasis and disease etiology have come to be understoodgradually over the past 40 years. However, due to the recentcloning and expression of receptors for ATP and adenosine, novelcompounds have been developed with unique therapeutic potential forthe treatment of thrombosis, stroke, epilepsy, chronic pain,immunological disorders, and cancer. As a result, the study ofadenosine- and ATP-mediated responses in cellular regulation isentering a phase of opportunity and development unmatched since thedays of serotonin receptor research in the 1970s. The only definitive book on the topic, Purinergic Approaches inExperimental Therapeutics covers all of the major therapeuticapplications of purinergic receptors and reflects the very latestdevelopments in this new area of therapeutic research. Twenty-eightchapters, authored by an international group of contributors whoare the leading authorities in the field, provide details onmolecular pharmacology; medicinal chemistry; and therapeuticimplications, including cardiology, metabolism, immunology,neurology, and cancer. Among the topics covered: * Purinergic Neurotransmission and Neuromodulation: A HistoricalPerspective * Adenosine Receptor Subtypes: New Insights from Cloning andFunctional Studies * Modulators of Adenosine Uptake, Release, and Inactivation * Cardiac Electrophysiology of Adenosine: Antiarrhythmic andProarrhythmic Actions * Purinergic Modulation of Gastrointestinal Function * The Role of Adenosine in Asthma * ATP in Brain Function * ATP in the Treatment of Cancer For researchers in pharmacology, physiology, molecular biology, andmedicinal chemistry, Purinergic Approaches in ExperimentalTherapeutics heralds an exciting new era in the understanding ofpurinergic neurotransmission and the development of noveltherapeutic modalities. Covers therapeutic applications of purinergic receptors and reflects the developments in this area of therapeutic research. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

Condizione: New. pp. 582 This item is printed on demand.

Hardcover. Condizione: Brand New. 1st edition. 581 pages. 9.75x6.50x1.25 inches. In Stock. This item is printed on demand.