Knobel philip (13 risultati)
- Brossura
Da: Beers Book Center, Sacramento, CA, U.S.A.Beers Book Center
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Come nuovo
EUR 2,66
EUR 4,30 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Trade Paperback. Condizione: Used - Like New. The book is in like new condition with only the slightest wear from handling.
- Brossura
Da: R Bookmark, Youngtown, AZ, U.S.A.R Bookmark
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Discreto
EUR 2,88
EUR 5,28 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Mass Market Paperback. Condizione: Used - Acceptable. Shelf and spine wear -- reader's copy. Pages yellowing from age.
- Brossura
Da: R Bookmark, Youngtown, AZ, U.S.A.R Bookmark
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Discreto
EUR 2,88
EUR 5,28 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Mass Market Paperback. Condizione: Used - Acceptable. Book twisting from being on shelf.
- Brossura
Da: ThriftBooks-Atlanta, AUSTELL, GA, U.S.A.ThriftBooks-Atlanta
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Discreto
EUR 8,85
Spedizione gratuitaSpedito in U.S.A.Quantità: 1 disponibili
Paperback. Condizione: Fair. No Jacket. Readable copy. Pages may have considerable notes/highlighting. ~ ThriftBooks: Read More, Spend Less.
- Brossura
Da: ThriftBooks-Dallas, Dallas, TX, U.S.A.ThriftBooks-Dallas
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Discreto
EUR 8,85
Spedizione gratuitaSpedito in U.S.A.Quantità: 1 disponibili
Paperback. Condizione: Fair. No Jacket. Readable copy. Pages may have considerable notes/highlighting. ~ ThriftBooks: Read More, Spend Less.
- Brossura
Da: ThriftBooks-Dallas, Dallas, TX, U.S.A.ThriftBooks-Dallas
Contatta il venditoreVenditore con 5 stelleCondizione: Usato - Buono
EUR 8,85
Spedizione gratuitaSpedito in U.S.A.Quantità: 1 disponibili
Paperback. Condizione: Good. No Jacket. Pages can have notes/highlighting. Spine may show signs of wear. ~ ThriftBooks: Read More, Spend Less.
Editore: Jove/HBJ, New York, NY, U.S.A., 1979
- Brossura
- Prima edizione
Da: Stuart W. Wells III, Norwalk, CT, U.S.A.Stuart W. Wells III
Contatta il venditoreVenditore con 4 stelleCondizione: Usato - Ottimo
EUR 8,87
EUR 4,31 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Aggiungi al carrelloMass Market Paperback. Condizione: Fine. First Edition. Publisher's Code M4870. As new, never read.
Editore: jove, 1979
- Brossura
- Prima edizione
Da: GRAHAM HOLROYD, BOOKS, webster, NY, U.S.A.GRAHAM HOLROYD, BOOKS
Contatta il venditoreVenditore con 5 stelleCondizione: Usato
EUR 8,87
EUR 6,03 spedizioneSpedito in U.S.A.Quantità: 1 disponibili
Aggiungi al carrelloPaperback. first edition. near fine, unread, , new looking paperback.
Lingua: Inglese
Editore: Südwestdeutscher Verlag für Hochschulschriften, 2015
- Brossura
Da: preigu, Osnabrück, Germaniapreigu
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 47,15
EUR 70,00 spedizioneSpedito da Germania a U.S.A.Quantità: 5 disponibili
Taschenbuch. Condizione: Neu. Translesion DNA Polymerases | Targeting Translesion DNA Synthesis in the Context of Cancer Therapy | Philip Alexander Knobel | Taschenbuch | 92 S. | Englisch | 2015 | Südwestdeutscher Verlag für Hochschulschriften | EAN 9783838120522 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengeri…cher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.
Lingua: Inglese
Editore: Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Jul 2015, 2015
- Brossura
- Print on Demand
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 53,90
EUR 23,00 spedizioneSpedito da Germania a U.S.A.Quantità: 2 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -While investigating the involvement of REV3, the catalytic subunit of TLS Polymerase zeta (Pol zeta) in the development of chemotherapy resistance, it was found that inhibition of REV3 expression per se suppresses colony formation…of cancer cells whereas normal cells were less affected. It was confirmed that inhibition of REV3 in various cancer cell lines leads to a growth inhibition, due to accumulation of persistent DNA damage, subsequently leading to the activation of the ATM-dependent DNA damage response (DDR) cascade. Inhibition of REV3 in p53-proficient cancer cells results in a G1-arrest and senescence. In contrast, the inhibition of REV3 in p53-deficient or p53-knockout cancer cells results in a growth inhibition and a G2/M-arrest whereas a small fraction of the p53-deficient or p53-knockout cancer cells can overcome the G2/M-arrest, which results in mitotic slippage and aneuploidy. It is shown for the first time that inhibition of a TLS Pol confers synthetic sickness/lethality specifically in cancer cells. The inhibition REV3 per se suppresses cancer cell growth whereas normal cells are less affected, thus identifying REV3 as a potential target for a cancer-specific therapy. 92 pp. Englisch.
Lingua: Inglese
Editore: Südwestdeutscher Verlag Für Hochschulschriften, 2011
- Brossura
- Print on Demand
Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 55,63
EUR 30,50 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - While investigating the involvement of REV3, the catalytic subunit of TLS Polymerase zeta (Pol zeta) in the development of chemotherapy resistance, it was found that inhibition of REV3 expression per se suppresses colony formation of ca…ncer cells whereas normal cells were less affected. It was confirmed that inhibition of REV3 in various cancer cell lines leads to a growth inhibition, due to accumulation of persistent DNA damage, subsequently leading to the activation of the ATM-dependent DNA damage response (DDR) cascade. Inhibition of REV3 in p53-proficient cancer cells results in a G1-arrest and senescence. In contrast, the inhibition of REV3 in p53-deficient or p53-knockout cancer cells results in a growth inhibition and a G2/M-arrest whereas a small fraction of the p53-deficient or p53-knockout cancer cells can overcome the G2/M-arrest, which results in mitotic slippage and aneuploidy. It is shown for the first time that inhibition of a TLS Pol confers synthetic sickness/lethality specifically in cancer cells. The inhibition REV3 per se suppresses cancer cell growth whereas normal cells are less affected, thus identifying REV3 as a potential target for a cancer-specific therapy.
Lingua: Inglese
Editore: Südwestdeutscher Verlag für Hochschulschriften, 2011
- Brossura
- Print on Demand
Da: moluna, Greven, Germaniamoluna
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 44,69
EUR 48,99 spedizioneSpedito da Germania a U.S.A.Quantità: Più di 20 disponibili
Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Knobel Philip AlexanderDissertation and study of Biology at the University of Zurich, Switzerland. Postdoctoral fellow at the Institute for Research in Biomedicine in Barcelona, Spain.While investigati…ng the involvement of REV3, .
Lingua: Inglese
Editore: Südwestdeutscher Verlag Für Hochschulschriften Dez 2011, 2011
- Brossura
- Print on Demand
Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
Contatta il venditoreVenditore con 5 stelleCondizione: Nuovo
EUR 53,90
EUR 60,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -While investigating the involvement of REV3, the catalytic subunit of TLS Polymerase zeta (Pol ¿) in the development of chemotherapy resistance, it was found that inhibition of REV3 expression per se suppresses colony formation of canc…er cells whereas normal cells were less affected. It was confirmed that inhibition of REV3 in various cancer cell lines leads to a growth inhibition, due to accumulation of persistent DNA damage, subsequently leading to the activation of the ATM-dependent DNA damage response (DDR) cascade. Inhibition of REV3 in p53-proficient cancer cells results in a G1-arrest and senescence. In contrast, the inhibition of REV3 in p53-deficient or p53-knockout cancer cells results in a growth inhibition and a G2/M-arrest whereas a small fraction of the p53-deficient or p53-knockout cancer cells can overcome the G2/M-arrest, which results in mitotic slippage and aneuploidy. It is shown for the first time that inhibition of a TLS Pol confers synthetic sickness/lethality specifically in cancer cells. The inhibition REV3 per se suppresses cancer cell growth whereas normal cells are less affected, thus identifying REV3 as a potential target for a cancer-specific therapy.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 92 pp. Englisch.
