Lipkovich ilya (52 risultati)

Paperback. Condizione: New.

Condizione: New.

Condizione: New.

Condizione: As New. Unread book in perfect condition.

Paperback. Condizione: New. Brand new book, sourced directly from publisher. Dispatch time is 7-8 days from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely.

Condizione: New.

Paperback. Condizione: New. Brand new book, sourced directly from publisher. Dispatch time is 7-8 days from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely.

Condizione: New.

Condizione: As New. Unread book in perfect condition.

Condizione: New.

Condizione: New.

Condizione: New.

Condizione: New.

Paperback. Condizione: New. 1st. The concepts of estimands, analyses (estimators), and sensitivity are interrelated. Therefore, great need exists for an integrated approach to these topics. This book acts as a practical guide to developing and implementing statistical analysis plans by explaining fundamental concepts using accessible language, providing technical details, real-world examples, and SAS and R code to implement analyses. The updated ICH guideline raises new analytic and cross-functional challenges for statisticians. Gaps between different communities have come to surface, such as between causal inference and clinical trialists, as well as among clinicians, statisticians, and regulators when it comes to communicating decision-making objectives, assumptions, and interpretations of evidence.This book lays out a path toward bridging some of these gaps. It offers¿ A common language and unifying framework along with the technical details and practical guidance to help statisticians meet the challenges¿ A thorough treatment of intercurrent events (ICEs), i.e., postrandomization events that confound interpretation of outcomes and five strategies for ICEs in ICH E9 (R1)¿ Details on how estimands, integrated into a principled study development process, lay a foundation for coherent specification of trial design, conduct, and analysis needed to overcome the issues caused by ICEs:¿ A perspective on the role of the intention-to-treat principle¿ Examples and case studies from various areas¿ Example code in SAS and R¿ A connection with causal inference¿ Implications and methods for analysis of longitudinal trials with missing dataTogether, the authors have offered the readers their ample expertise in clinical trial design and analysis, from an industrial and academic perspective.…

Condizione: New.

Condizione: New. 1st edition NO-PA16APR2015-KAP.

Condizione: As New. Unread book in perfect condition.

Condizione: New. 1st edition NO-PA16APR2015-KAP.

Condizione: New.

Condizione: As New. Unread book in perfect condition.

Condizione: New.

Paperback. Condizione: New. Analyzing Longitudinal Clinical Trial Data: A Practical Guide provides practical and easy to implement approaches for bringing the latest theory on analysis of longitudinal clinical trial data into routine practice.The book, with its example-oriented approach that includes numerous SAS and R code fragments, is an essential resource for statisticians and graduate students specializing in medical research. The authors provide clear descriptions of the relevant statistical theory and illustrate practical considerations for modeling longitudinal data. Topics covered include choice of endpoint and statistical test; modeling means and the correlations between repeated measurements; accounting for covariates; modeling categorical data; model verification; methods for incomplete (missing) data that includes the latest developments in sensitivity analyses, along with approaches for and issues in choosing estimands; and means for preventing missing data. Each chapter stands alone in its coverage of a topic. The concluding chapters provide detailed advice on how to integrate these independent topics into an over-arching study development process and statistical analysis plan.…

hardcover. Condizione: Good. Connecting readers with great books since 1972! Used textbooks may not include companion materials such as access codes, etc. May have some wear or writing/highlighting. We ship orders daily and Customer Service is our top priority.

Paperback. Condizione: Brand New. 318 pages. 9.19x6.13x0.75 inches. In Stock.

Paperback. Condizione: Brand New. 336 pages. 9.21x6.14x0.71 inches. In Stock.

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Hardcover. Condizione: Brand New. 295 pages. 9.25x6.25x0.75 inches. In Stock.

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Condizione: New.