Hardcover. Condizione: Very Good. No Jacket. Former library book; May have limited writing in cover pages. Pages are unmarked. ~ ThriftBooks: Read More, Spend Less.
Da: killarneybooks, Inagh, CLARE, Irlanda
Prima edizione
EUR 65,50
Quantità: 1 disponibili
Aggiungi al carrelloHardcover. Condizione: Good. 1st Edition. Oversized hardcover, xv + 352 pages, NOT ex-library. Shipping weight over 1kg. Great interior, clean and bright throughout with unmarked text, free of inscriptions and stamps, firmly bound. An external 'mängelexemplar' stamp on the upper outer page edges. Torn & glued tips of the lower outer corners of the boards. Issued without a dust jacket. -- A guide to modern computational tools used to design and refine drug candidates, it focuses on how molecular simulations can complement or even replace traditional laboratory assays to produce faster, more accurate results in drug design. Core Themes and Structure: The book is organized into three distinct parts that transition from theoretical foundations to practical real-world use: Part I: Principles: Introduces the fundamental tools used in biomolecular simulation, describing common methodologies for modeling drugs and their targets while analyzing the accuracy of these predictions. Part II: Advanced Algorithms: Explores specialized techniques like enhanced sampling, which helps researchers observe rare molecular events, and Markov State Models to understand the long-term dynamics of protein-ligand binding. Part III: Applications and Success Stories: Presents case studies where these computational methods were successfully applied in real-life drug discovery projects. Key Scientific Focus: - Dynamics over Rigidity [moving beyond viewing proteins as static structures, the text emphasizes protein flexibility and how understanding its movement is crucial for designing potent compounds against dynamic drug targets like RAS proteins]; - Integration with Data [a major focus is on how to integrate computational modeling with other experimental data, such as X-ray and NMR findings, to refine molecular structures]; - Accuracy of Force Fields [the authors provide a detailed discussion on the strengths and limitations of molecular mechanics (MM) force fields, which are the mathematical models used to calculate the energy of molecular systems. The work is specifically written for medicinal chemists, structural biologists, and pharmaceutical industry professionals. It is designed to be accessible to students and newcomers while providing the in-depth methodological detail required by experienced researchers.
Lingua: Inglese
Editore: Vch Verlagsgesellschaft Mbh, Germany, 2005
ISBN 10: 3527307532 ISBN 13: 9783527307531
Da: Charlie Byrne's Bookshop, Galway, GALWA, Irlanda
EUR 62,28
Quantità: 1 disponibili
Aggiungi al carrelloHardcover. Condizione: As New. In mint Condition. Volume 23.
Lingua: Inglese
Editore: Vch Verlagsgesellschaft Mbh, Germany, 2005
ISBN 10: 3527307532 ISBN 13: 9783527307531
Da: Charlie Byrne's Bookshop, Galway, GALWA, Irlanda
EUR 62,28
Quantità: 1 disponibili
Aggiungi al carrelloHardcover. Condizione: As New. In mint Condition. Volume 23.
Da: Roland Antiquariat UG haftungsbeschränkt, Weinheim, Germania
Prima edizione
EUR 60,00
Quantità: 1 disponibili
Aggiungi al carrelloHardcover/Pappeinband. 1. Auflage. XVI, 262 S. : Ill., graph. Darst. ; 25 cm Very good condition. Name entry on flyleaf. Reading pages are clean and without marks. Book shows slight storage signs. No dust jacket. Still very good copy. 9783527306787 Sprache: Englisch Gewicht in Gramm: 699.
Da: Frey Fine Books, Rougemont, NC, U.S.A.
Prima edizione
Hardcover. Condizione: Near Fine. 1st edition. 1st edition. A Near Fine copy. 4to., xxx, 471 pp., illustrated with charts,graphs, and diagrams. Bound in white with blue spine, glossy, paper boards. Part of the publisher's series, Methods and Principles in Medicinal Chemistry, this being volume 37 in that series.
Hardcover. Condizione: New. In shrink wrap. Looks like an interesting title!
Da: Basi6 International, Irving, TX, U.S.A.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Da: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.
Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Da: SMASS Sellers, IRVING, TX, U.S.A.
Condizione: New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed.
Da: SMASS Sellers, IRVING, TX, U.S.A.
Condizione: New. Brand New Original US Edition. Customer service! Satisfaction Guaranteed.
Da: suspiratio - online bücherstube lic.phil h.b., Basel, Svizzera
Prima edizione
EUR 79,00
Quantità: 1 disponibili
Aggiungi al carrelloHardcover. Condizione: Sehr gut. 1. Auflage. SEHR GUT HARDCOVER, 404 PP.
Da: Studibuch, Stuttgart, Germania
EUR 67,19
Quantità: 1 disponibili
Aggiungi al carrellohardcover. Condizione: Gut. 816 Seiten; 9783527341498.3 Gewicht in Gramm: 4.
Da: GreatBookPrices, Columbia, MD, U.S.A.
Condizione: New.
Da: GreatBookPricesUK, Woodford Green, Regno Unito
EUR 117,61
Quantità: 2 disponibili
Aggiungi al carrelloCondizione: New.
EUR 137,58
Quantità: Più di 20 disponibili
Aggiungi al carrelloCondizione: New.
EUR 29,90
Quantità: 1 disponibili
Aggiungi al carrelloCondizione: Sehr gut. Zustand: Sehr gut | Seiten: 380 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
Da: GreatBookPrices, Columbia, MD, U.S.A.
Condizione: As New. Unread book in perfect condition.
Da: Books Puddle, New York, NY, U.S.A.
Condizione: New.
EUR 141,58
Quantità: Più di 20 disponibili
Aggiungi al carrelloCondizione: As New. Unread book in perfect condition.
Da: Majestic Books, Hounslow, Regno Unito
EUR 138,94
Quantità: 4 disponibili
Aggiungi al carrelloCondizione: New.
Da: GreatBookPricesUK, Woodford Green, Regno Unito
EUR 126,24
Quantità: Più di 20 disponibili
Aggiungi al carrelloCondizione: New.
EUR 93,44
Quantità: 1 disponibili
Aggiungi al carrelloCondizione: New. Helga Ruebsamen-Schaeff, PhD, is founding CEO of AiCuris and the chair of AiCuris Scientific Advisory Board. Before founding AiCuris she served at Bayer as SVP and Head of Infectious Disease Research. Before that time, she was Scientific and Managing Direct.
Da: Chiron Media, Wallingford, Regno Unito
EUR 129,45
Quantità: 3 disponibili
Aggiungi al carrelloHardcover. Condizione: New.
Condizione: New.
Condizione: New. pp. 594.
Da: Biblios, Frankfurt am main, HESSE, Germania
EUR 139,43
Quantità: 4 disponibili
Aggiungi al carrelloCondizione: New.
EUR 146,54
Quantità: 4 disponibili
Aggiungi al carrelloCondizione: New. pp. 594.
Condizione: As New. Unread book in perfect condition.
Da: GreatBookPricesUK, Woodford Green, Regno Unito
EUR 140,20
Quantità: 2 disponibili
Aggiungi al carrelloCondizione: As New. Unread book in perfect condition.