melissa ellen elder (6 risultati)

PAP. Condizione: New. New Book. Shipped from UK. Established seller since 2000.

PAP. Condizione: New. New Book. Shipped from UK. Established seller since 2000.

HRD. Condizione: New. New Book. Shipped from UK. Established seller since 2000.

HRD. Condizione: New. New Book. Shipped from UK. Established seller since 2000.

Paperback. Condizione: New. Print on Demand. This book explores the complex relationship between autoimmunity and immunodeficiency in the spontaneously diabetic BB rat model, providing valuable insights into the pathogenesis of insulin-dependent diabetes (IDD). The author delves into the historical context of IDD research and positions the BB rat model within its significance in understanding the disease. The book comprehensively examines the immune dysregulation observed in BB rats, including the presence of organ-specific autoantibodies, impaired T cell function, and increased susceptibility to infections. The author discusses the potential mechanisms underlying these abnormalities, such as genetic predisposition and environmental factors. Through detailed analyses, the book highlights the similarities and differences between IDD in BB rats and humans, emphasizing the translational potential of this model for studying the disease. The author explores the role of autoimmunity in the development of IDD, examining the presence of pancreatic islet cell antibodies and other autoimmune markers in BB rats. This book offers a comprehensive understanding of the immune dysregulation and autoimmunity in the BB rat model, providing valuable insights for researchers and clinicians working in the field of diabetes and immunology. The author effectively synthesizes current knowledge and presents a compelling argument for the continued use of the BB rat model to unravel the complexities of IDD. This book is a reproduction of an important historical work, digitally reconstructed using state-of-the-art technology to preserve the original format. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in the book. print-on-demand item.

LeatherBound. Condizione: New. BOOKS ARE EXEMPT FROM IMPORT DUTIES AND TARIFFS; NO EXTRA CHARGES APPLY. LeatherBound edition. Condition: New. Reprinted from 1982 edition. Leather Binding on Spine and Corners with Golden leaf printing on spine. Bound in genuine leather with Satin ribbon page markers and Spine with raised gilt bands. A perfect gift for your loved ones. Pages: 197 NO changes have been made to the original text. This is NOT a retyped or an ocr'd reprint. Illustrations, Index, if any, are included in black and white. Each page is checked manually before printing. As this print on demand book is reprinted from a very old book, there could be some missing or flawed pages, but we always try to make the book as complete as possible. Fold-outs, if any, are not part of the book. If the original book was published in multiple volumes then this reprint is of only one volume, not the whole set. Sewing binding for longer life, where the book block is actually sewn (smythe sewn/section sewn) with thread before binding which results in a more durable type of binding. Pages: 197.