Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: SMASS Sellers, IRVING, TX, U.S.A.
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Lingua: Inglese
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ISBN 10: 1849730504 ISBN 13: 9781849730501
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Editore: Royal Society of Chemistry RSC, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Books Puddle, New York, NY, U.S.A.
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Aggiungi al carrelloCondizione: New. pp. 286 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Biblios, Frankfurt am main, HESSE, Germania
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Aggiungi al carrelloCondizione: New. pp. 286.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Basi6 International, Irving, TX, U.S.A.
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Basi6 International, Irving, TX, U.S.A.
Condizione: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.
Condizione: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Basi6 International, Irving, TX, U.S.A.
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Romtrade Corp., STERLING HEIGHTS, MI, U.S.A.
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Aggiungi al carrelloCondizione: Sehr gut. Zustand: Sehr gut | Seiten: 270 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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ISBN 10: 1849730504 ISBN 13: 9781849730501
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Aggiungi al carrelloHardback. Condizione: New. Since Alois Alzheimer described the results of his postmortem studies in 1906, significant strides have been made in understanding the pathogenesis of neurodegenerative diseases. Substantial evidence has accumulated indicating that diverse neurodegenerative disorders might share a common pathological mechanism: the misfolding, aggregation and accumulation of proteins (termed "amyloid") in the brain. Metal ions have long been thought to catalyze protein misfolding initiating a cascade of events resulting in oxidative damage and neurodegeneration. They have, consequently, been seen as a suitable pharmacological target. However, drugs aimed at simply removing excess metals or interfering in amyloid deposition were unsuccessful and scientists have been forced to review the classical hypothesis. The latest advances suggest that deficiencies in protein homeostasis may lead to cell dysfunction and disease. Furthermore, small molecules with the potential to control metal homeostasis, or metallostasis, are expected to provide the framework for the design of novel proteostasis regulators. This book provides an up-date on the latest developments in this fast moving field. Traditional views concerning the relationship between the physio-pathological cycles of copper, zinc, iron, aluminium and the evolution of life, are compared with emerging ideas in the neuroscience of metal ions. Topics covered emphasize the importance of metals and oxidation chemistry to neuroscientists as well as providing a wider, multidisciplinary background to chemists who are attracted by these fascinating subjects. The text starts with a chapter on chemical evolution, the brain and metallomics which describes the brain's natural defences to adverse conditions. It then goes on to cover the chemistry and biology of proteostasis, environmental factors, and the role played by membranes in protein misfolding. The remaining chapters cover the role of metals and oxidative stress in Alzheimer's Disease, Parkinsonism, ALS and other neurodegenerative diseases. The book is suitable for academics, those working in industry, and postgraduate students.
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Aggiungi al carrelloHRD. Condizione: New. New Book. Shipped from UK. Established seller since 2000.
HRD. Condizione: New. New Book. Shipped from UK. Established seller since 2000.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Editore: Royal Society of Chemistry, 2011
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Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Aggiungi al carrelloCondizione: New. In.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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Aggiungi al carrelloHardback. Condizione: New. New copy - Usually dispatched within 4 working days.
Lingua: Inglese
Editore: Royal Society of Chemistry, GB, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
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EUR 157,09
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Aggiungi al carrelloHardback. Condizione: New. Since Alois Alzheimer described the results of his postmortem studies in 1906, significant strides have been made in understanding the pathogenesis of neurodegenerative diseases. Substantial evidence has accumulated indicating that diverse neurodegenerative disorders might share a common pathological mechanism: the misfolding, aggregation and accumulation of proteins (termed "amyloid") in the brain. Metal ions have long been thought to catalyze protein misfolding initiating a cascade of events resulting in oxidative damage and neurodegeneration. They have, consequently, been seen as a suitable pharmacological target. However, drugs aimed at simply removing excess metals or interfering in amyloid deposition were unsuccessful and scientists have been forced to review the classical hypothesis. The latest advances suggest that deficiencies in protein homeostasis may lead to cell dysfunction and disease. Furthermore, small molecules with the potential to control metal homeostasis, or metallostasis, are expected to provide the framework for the design of novel proteostasis regulators. This book provides an up-date on the latest developments in this fast moving field. Traditional views concerning the relationship between the physio-pathological cycles of copper, zinc, iron, aluminium and the evolution of life, are compared with emerging ideas in the neuroscience of metal ions. Topics covered emphasize the importance of metals and oxidation chemistry to neuroscientists as well as providing a wider, multidisciplinary background to chemists who are attracted by these fascinating subjects. The text starts with a chapter on chemical evolution, the brain and metallomics which describes the brain's natural defences to adverse conditions. It then goes on to cover the chemistry and biology of proteostasis, environmental factors, and the role played by membranes in protein misfolding. The remaining chapters cover the role of metals and oxidative stress in Alzheimer's Disease, Parkinsonism, ALS and other neurodegenerative diseases. The book is suitable for academics, those working in industry, and postgraduate students.
Lingua: Inglese
Editore: Royal Society of Chemistry, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: Mispah books, Redhill, SURRE, Regno Unito
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Aggiungi al carrelloHardcover. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
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Aggiungi al carrelloCondizione: New. Brand New ! Fast Delivery "International Edition " and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 4-6 Working days .and we do have flat rate for up to 2LB. Extra shipping charges will be requested This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.
Lingua: Inglese
Editore: ROYAL SOCIETY OF CHEMISTRY, 2011
ISBN 10: 1849730504 ISBN 13: 9781849730501
Da: moluna, Greven, Germania
EUR 169,50
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Aggiungi al carrelloGebunden. Condizione: New. This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.Über den AutorrnrnDanilo Milardi obtained a degree in Industrial Chemistry from the University of Catania before going on to obtain a PhD.
Da: UK BOOKS STORE, London, LONDO, Regno Unito
EUR 228,40
Quantità: 3 disponibili
Aggiungi al carrelloHardcover. Condizione: New. Brand New ! Fast Delivery "International Edition " and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 4-6 Working days .and we do have flat rate for up to 2LB. Extra shipping charges will be requested This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.