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Aggiungi al carrelloHardcover. Condizione: New. No Jacket. 1st Edition. Brand New. Hardback copy in pictorial boards, no dustjacket as issued. 564pp. Illustrated throughout. Blood-brain barrier (BBB) breakdown leading to cerebral edema occurs in many brain diseases-such as trauma, stroke, inflammation, infection, and tumors-and is an important factor in the mortality arising from these con- tions. Despite the importance of the BBB in the pathogenesis of these diseases, the molecular mechanisms occurring at the BBB are not completely und- stood. In the last decade a number of molecules have been identified not only in endothelial cells, but also in astrocytes, pericytes, and the perivascular cells that interact with endothelium to maintain cerebral homeostasis. However, the precise cellular interactions at a molecular level in steady states and d- eases have still to be determined. The introduction of new research techniques during the last decade or so provide an opportunity to study the molecular mec- nisms occurring at the BBB in diseases. The Blood-Brain Barrier: Biology and Research Protocols provides the reader with details of selected morphologic, permeability, transport, in vitro, and molecular techniques for BBB studies, all written by experts in the field. Each part is preceded by a review that emphasizes the advantages and pitfalls of particular techniques, as well as offering much relevant current information. The techniques provided will be helpful to both beginners in BBB research and those more experienced investigators who wish to add a specific technique to those already available in their laboratories. (50/4).
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hardcover. Condizione: New. In shrink wrap. Looks like an interesting title!
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Aggiungi al carrelloCondizione: Sehr gut. Zustand: Sehr gut | Seiten: 564 | Sprache: Englisch | Produktart: Bücher | Blood¿brain barrier (BBB) breakdown leading to cerebral edema occurs in many brain diseases¿such as trauma, stroke, inflammation, infection, and tumors¿and is an important factor in the mortality arising from these con- tions. Despite the importance of the BBB in the pathogenesis of these diseases, the molecular mechanisms occurring at the BBB are not completely und- stood. In the last decade a number of molecules have been identified not only in endothelial cells, but also in astrocytes, pericytes, and the perivascular cells that interact with endothelium to maintain cerebral homeostasis. However, the precise cellular interactions at a molecular level in steady states and d- eases have still to be determined. The introduction of new research techniques during the last decade or so provide an opportunity to study the molecular mec- nisms occurring at the BBB in diseases. The Blood¿Brain Barrier: Biology and Research Protocols provides the reader with details of selected morphologic, permeability, transport, in vitro, and molecular techniques for BBB studies, all written by experts in the field. Each part is preceded by a review that emphasizes the advantages and pitfalls of particular techniques, as well as offering much relevant current information. The techniques provided will be helpful to both beginners in BBB research and those more experienced investigators who wish to add a specific technique to those already available in their laboratories.
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Aggiungi al carrelloCondizione: Sehr gut. Zustand: Sehr gut | Seiten: 516 | Sprache: Englisch | Produktart: Bücher | Evolving technologies starting with tracer studies, and more recently with genomics and proteomics, have provided novel information about the molecular properties of cerebral endothelium and astrocytes; however, further studies must be done in animal models of neurological diseases and in humans to get a clearer understanding of the pathogenesis of blood-brain barrier (BBB) breakdown in nervous system diseases. In The Blood-Brain and Other Neural Barriers: Reviews and Protocols, experts in the field present a series of cutting-edge protocols which can be used to study the barriers. Opening with detailed information on components of the neurovascular unit as well as the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, the book continues with meticulous techniques to image the barriers in humans and experimental animals, followed by cutting-edge molecular techniques to study the BBB and novel models to study the barriers, and it concludes with techniques for the delivery of therapeutic agents across the BBB. Written in the highly successful Methods in Molecular Biology¿ series format, protocol chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and up-to-date, The Blood-Brain and Other Neural Barriers: Reviews and Protocols will aid the research efforts of not only graduate students but also more experienced investigators and support future studies of these vital systems.
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Aggiungi al carrelloCondizione: New. Editor(s): Nag, Sukriti. Series: Methods in Molecular Medicine. Num Pages: 550 pages, biography. BIC Classification: PSAN. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 29. Weight in Grams: 1172. . 2010. Softcover reprint of hardcover 1st ed. 2003. paperback. . . . .
Condizione: New. pp. XIV, 502 Softcover reprint of the original 1st ed. 2011 edition NO-PA16APR2015-KAP.
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Aggiungi al carrelloCondizione: New. This text provides investigators with details of selected morphologic, permeability, transport, in vitro and molecular techniques for BBB studies. Series: Methods in Molecular Medicine. Num Pages: 550 pages, biography. BIC Classification: MJF. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 32. Weight in Grams: 1368. . 2003. Hardback. . . . .
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Aggiungi al carrelloTaschenbuch. Condizione: Neu. The Blood-Brain and Other Neural Barriers | Reviews and Protocols | Sukriti Nag | Taschenbuch | xiv | Englisch | 2016 | Humana | EAN 9781493961443 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Condizione: New. Editor(s): Nag, Sukriti. Series: Methods in Molecular Medicine. Num Pages: 550 pages, biography. BIC Classification: PSAN. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 29. Weight in Grams: 1172. . 2010. Softcover reprint of hardcover 1st ed. 2003. paperback. . . . . Books ship from the US and Ireland.
Condizione: New. This text provides investigators with details of selected morphologic, permeability, transport, in vitro and molecular techniques for BBB studies. Series: Methods in Molecular Medicine. Num Pages: 550 pages, biography. BIC Classification: MJF. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 32. Weight in Grams: 1368. . 2003. Hardback. . . . . Books ship from the US and Ireland.
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Aggiungi al carrelloHardcover. Condizione: Brand New. 1st edition. 549 pages. 10.25x9.75x1.25 inches. In Stock.
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Condizione: New. 2016. Paperback. . . . . . Books ship from the US and Ireland.
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Aggiungi al carrelloCondizione: New. Opening with components of the neurovascular unit and the blood-cerebrospinal, blood-retinal, and blood-nerve barriers, this book reviews imaging techniques, molecular study methods, and techniques for delivering therapeutic agents across the BBB. Editor(s): Nag, Sukriti. Series: Methods in Molecular Biology. Num Pages: 502 pages, 21 black & white tables, biography. BIC Classification: MFG; MJN; PSAN. Category: (P) Professional & Vocational. Dimension: 259 x 182 x 28. Weight in Grams: 1104. . 2010. Hardback. . . . .