Oesch j m (17 risultati)
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Da: Emile Kerssemakers ILAB, Heerlen, Paesi BassiEmile Kerssemakers ILAB
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24 cm. original paperback. viii,336 pp. some ills, diagrams. references. index. ISBN New York: 0387095845. "Archives of Toxicology / Archiv für Toxikologie". -(libr label, library stamps, with plasticized cover (einbandfolie), signs of use, otherwise good). 620g.
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Da: Roland Antiquariat UG haftungsbeschränkt, Weinheim, GermaniaRoland Antiquariat UG haftungsbeschränkt
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EUR 85,00
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Softcover. VII, 336 S. : 64 Ill. u. graph. Darst. ; 25 cm Good condition. Reading pages are very clean and without marks. Retired library exemplar. Slight traces of storage or usage. Otherwise very good exemplar. 9783540095842 Sprache: Englisch Gewicht in Gramm: 649 Softcover reprint of the original 1st ed. 1980.
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Da: Ria Christie Collections, Uxbridge, Regno UnitoRia Christie Collections
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EUR 116,65
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Condizione: New. In.
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Da: Books Puddle, New York, NY, U.S.A.Books Puddle
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EUR 144,18
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Condizione: New. pp. 348.
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Da: Buchpark, Trebbin, GermaniaBuchpark
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EUR 42,90
EUR 105,00 spedizioneSpedito da Germania a U.S.A.Quantità: 1 disponibili
Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 348 | Sprache: Englisch | Produktart: Bücher | N-nitroso-compounds form an important class of carcinogenic chemicals which may be of environmental importance (Druckrey et al. , 1967; Magee et al. , 1976; IARC, 1978). The mechanism by which these carcinogens initiate neoplastic gr…owth is not well understood but there is substantial evidence favoring the hypothesis that the simple dialkylnitrosamines and alkylnitrosamides act by means of their conversion to al kylating agents. Alkylating species are generated from the nitrosamines by metabolic activation and from the nitrosamides by chemical decomposition at physiological pH. It is widely believed that DNA is the critical alkylation target. Alkylation takes place at at least 12 sites within the DNA molecule (Lawley, 1976; Singer, 1976; Pegg, 1977a). Al though alkylation at the 7-position of guanine is the most extensive reaction with the DNA bases and provides a reliable measurement of the degree of interaction with the carcinogen (Swann and Magee, 1968, 1971), recent experiments have suggested that alkylation of oxygen atoms may be the critical reaction (Goth and Rajewsky, 1974; Margison and Kleihues, 1975; Nicoll et aI. , 1975; Pegg, 1977a). These laboratories have observed a correlation between the production and persistence of 06-alkyl guanine and the occurrence oftumors in a variety of organs of rodents exposed to N-ni troso-carcinogens. It has, therefore, been suggested that the ability of tissues to catalyze the removal of 06-alkylguanine from DNA may provide a protective mechanism against carcinogenesis.
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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EUR 153,25
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Paperback. Condizione: Brand New. 348 pages. 9.61x6.69x0.79 inches. In Stock.
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Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH
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EUR 106,99
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Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - N-nitroso-compounds form an important class of carcinogenic chemicals which may be of environmental importance (Druckrey et al. , 1967; Magee et al. , 1976; IARC, 1978). The mechanism by which these carcinogens initiate neoplastic growth is not we…ll understood but there is substantial evidence favoring the hypothesis that the simple dialkylnitrosamines and alkylnitrosamides act by means of their conversion to al kylating agents. Alkylating species are generated from the nitrosamines by metabolic activation and from the nitrosamides by chemical decomposition at physiological pH. It is widely believed that DNA is the critical alkylation target. Alkylation takes place at at least 12 sites within the DNA molecule (Lawley, 1976; Singer, 1976; Pegg, 1977a). Al though alkylation at the 7-position of guanine is the most extensive reaction with the DNA bases and provides a reliable measurement of the degree of interaction with the carcinogen (Swann and Magee, 1968, 1971), recent experiments have suggested that alkylation of oxygen atoms may be the critical reaction (Goth and Rajewsky, 1974; Margison and Kleihues, 1975; Nicoll et aI. , 1975; Pegg, 1977a). These laboratories have observed a correlation between the production and persistence of 06-alkyl guanine and the occurrence oftumors in a variety of organs of rodents exposed to N-ni troso-carcinogens. It has, therefore, been suggested that the ability of tissues to catalyze the removal of 06-alkylguanine from DNA may provide a protective mechanism against carcinogenesis.
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Da: Mispah books, Redhill, SURRE, Regno UnitoMispah books
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EUR 183,01
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Paperback. Condizione: Very Good. Dust Jacket may NOT BE INCLUDED.CDs may be missing. SHIPS FROM MULTIPLE LOCATIONS. book.
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Da: BUCHSERVICE / ANTIQUARIAT Lars Lutzer, Wahlstedt, GermaniaBUCHSERVICE / ANTIQUARIAT Lars Lutzer
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EUR 249,90
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Condizione: gut. 1980. Quantitative aspects of risk assessment in chemical carcinogenesis : symposium held in Rome/Italy, April 3 - 6, 1979 / ed. by J. Clemmesen . Techn. ed. A. Waring / Archives of toxicology / Supplement ; 3 In deutscher Sprache. pages.
Editore: Tyrolia Innsbruck 1985, 1985
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- Prima edizione
Da: Antiquariat Buchtip Vera Eder-Haumer, Wien, W, AustriaAntiquariat Buchtip Vera Eder-Haumer
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1. Auflage. Sprache: Deutsch 191 Seiten, Oln mit Su / Leinen mit Schutzumschlag / Hardcover Großformat 4° / Quart / Großformat durchgehend Abbildungen, Ex Libris, sehr guter Zustand.
Lingua: Inglese
Editore: Springer Berlin Heidelberg, Springer Berlin Heidelberg Jun 1980, 1980
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- Print on Demand
Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 106,99
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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -N-nitroso-compounds form an important class of carcinogenic chemicals which may be of environmental importance (Druckrey et al. , 1967; Magee et al. , 1976; IARC, 1978). The mechanism by which these carcinogens initiate neoplastic…growth is not well understood but there is substantial evidence favoring the hypothesis that the simple dialkylnitrosamines and alkylnitrosamides act by means of their conversion to al kylating agents. Alkylating species are generated from the nitrosamines by metabolic activation and from the nitrosamides by chemical decomposition at physiological pH. It is widely believed that DNA is the critical alkylation target. Alkylation takes place at at least 12 sites within the DNA molecule (Lawley, 1976; Singer, 1976; Pegg, 1977a). Al though alkylation at the 7-position of guanine is the most extensive reaction with the DNA bases and provides a reliable measurement of the degree of interaction with the carcinogen (Swann and Magee, 1968, 1971), recent experiments have suggested that alkylation of oxygen atoms may be the critical reaction (Goth and Rajewsky, 1974; Margison and Kleihues, 1975; Nicoll et aI. , 1975; Pegg, 1977a). These laboratories have observed a correlation between the production and persistence of 06-alkyl guanine and the occurrence oftumors in a variety of organs of rodents exposed to N-ni troso-carcinogens. It has, therefore, been suggested that the ability of tissues to catalyze the removal of 06-alkylguanine from DNA may provide a protective mechanism against carcinogenesis. 348 pp. Englisch.
Quantitative Aspects of Risk Assessment in Chemical Carcinogenesis
Clemmesen, J.|Conning, D. M.|Henschler, D.|Oesch, F.|Waring, A.
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Da: moluna, Greven, Germaniamoluna
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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Dose Response Relationship in Long-Term Exposure to Low Levels of Carcinogens in Animals.- Epidemiological Studies of Occupational Carcinogens.- Incidence of Hepato-Carcinoma in Relation to Aflatoxin Intake.- Epidemi…ological Studies of Medically Used Drugs.
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- Print on Demand
Da: Majestic Books, Hounslow, Regno UnitoMajestic Books
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EUR 148,38
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Condizione: New. Print on Demand pp. 348 64 Figures, 67:B&W 6.69 x 9.61 in or 244 x 170 mm (Pinched Crown) Perfect Bound on White w/Gloss Lam.
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Da: Revaluation Books, Exeter, Regno UnitoRevaluation Books
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Hardcover. Condizione: Brand New. 370 pages. 9.60x6.40x1.10 inches. In Stock. This item is printed on demand.
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- Print on Demand
Da: Biblios, frankfurt am main, HESSE, GermaniaBiblios
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Condizione: New. PRINT ON DEMAND pp. 348.
Altre immagini- Brossura
- Print on Demand
Da: preigu, Osnabrück, Germaniapreigu
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Taschenbuch. Condizione: Neu. Quantitative Aspects of Risk Assessment in Chemical Carcinogenesis | Symposium held in Rome/Italy, April 3-6, 1979 | D. M. Conning (u. a.) | Taschenbuch | viii | Englisch | 1980 | Springer Vieweg | EAN 9783540095842 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121…Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand.
Lingua: Inglese
Editore: Springer Berlin Heidelberg, Springer Vieweg Jun 1980, 1980
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Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000
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EUR 106,99
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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -N-nitroso-compounds form an important class of carcinogenic chemicals which may be of environmental importance (Druckrey et al. , 1967; Magee et al. , 1976; IARC, 1978). The mechanism by which these carcinogens initiate neoplastic grow…th is not well understood but there is substantial evidence favoring the hypothesis that the simple dialkylnitrosamines and alkylnitrosamides act by means of their conversion to al kylating agents. Alkylating species are generated from the nitrosamines by metabolic activation and from the nitrosamides by chemical decomposition at physiological pH. It is widely believed that DNA is the critical alkylation target. Alkylation takes place at at least 12 sites within the DNA molecule (Lawley, 1976; Singer, 1976; Pegg, 1977a). Al though alkylation at the 7-position of guanine is the most extensive reaction with the DNA bases and provides a reliable measurement of the degree of interaction with the carcinogen (Swann and Magee, 1968, 1971), recent experiments have suggested that alkylation of oxygen atoms may be the critical reaction (Goth and Rajewsky, 1974; Margison and Kleihues, 1975; Nicoll et aI. , 1975; Pegg, 1977a). These laboratories have observed a correlation between the production and persistence of 06-alkyl guanine and the occurrence oftumors in a variety of organs of rodents exposed to N-ni troso-carcinogens. It has, therefore, been suggested that the ability of tissues to catalyze the removal of 06-alkylguanine from DNA may provide a protective mechanism against carcinogenesis.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.
