R m jayadeepa (47 risultati)

Condizione: New.

Taschenbuch. Condizione: Neu. Toxins as Medicine | Insilico Drug Discovery Approach on Toxins | Jayadeepa R. M | Taschenbuch | 148 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783844399769 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.…

Paperback. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Paperback. Condizione: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Condizione: New.

Taschenbuch. Condizione: Neu. Révéler le cancer de l'endomètre | L'approche Insilico de découverte de médicaments sur le cancer de l'endomètre | Jayadeepa R. M | Taschenbuch | Französisch | 2021 | Editions Notre Savoir | EAN 9786203292602 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

Condizione: New.

Taschenbuch. Condizione: Neu. Niet onthullende baarmoederkanker | Insilico Drug Discovery-benadering voor endometriumkanker | Jayadeepa R. M | Taschenbuch | Niederländisch | 2021 | Uitgeverij Onze Kennis | EAN 9786203292695 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

Condizione: New.

Condizione: New.

Condizione: New.

Taschenbuch. Condizione: Neu. Revelação do cancro endometrial | Abordagem Insilico de Descoberta de Drogas sobre o Cancro Endometrial | Jayadeepa R. M | Taschenbuch | Portugiesisch | 2021 | Edições Nosso Conhecimento | EAN 9786203292770 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

Taschenbuch. Condizione: Neu. Nieujawniony rak endometrium | Podej¿cie Insilico do odkrywania leków na raka endometrium | Jayadeepa R. M | Taschenbuch | Polnisch | 2021 | Wydawnictwo Nasza Wiedza | EAN 9786203292749 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

Taschenbuch. Condizione: Neu. Cancro endometriale non rivelato | Approccio insilico di scoperta della droga sul cancro endometriale | Jayadeepa R. M | Taschenbuch | Italienisch | 2021 | Edizioni Sapienza | EAN 9786203292664 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Taschenbuch. Condizione: Neu. Unentdecktes Endometriumkarzinom | Insilico Drug Discovery Ansatz bei Endometriumkrebs | Jayadeepa R. M | Taschenbuch | 124 S. | Deutsch | 2021 | Verlag Unser Wissen | EAN 9786203292558 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Traditionally, drugs were discovered by testing compounds synthesized in time consuming multi-step processes against a battery of in vivo biological screens. Promising compounds were then further studied in development, where their pharmaceutical properties, metabolism and potential toxicity were investigated. Here we present a study on herbal lead compounds and their potential binding affinity to the effectors molecules of major diseases like endometrial cancer. Clinical studies demonstrate a positive correlation between the extent of PDK1 and malignant progression of pre cancerous lesions in endometrial. Therefore, identification of effective, well-tolerated anti cancer inhibitor represents a rational chemo preventive strategy. This study has investigated the effects of naturally occurring compounds that inhibits the target. Our results reveal that these compounds use less energy to bind to the target and inhibit its activity than the commercial drugs used. Their high legend binding activity to the target introduce the prospect for their use in chemo preventive applications in addition they are freely available natural compounds that can be safely used to prevent disease. 116 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The toxins has a wonderful characteristics & medicinal values from marine sources which can be handy for researchers working on neuro-degenerative diseases.Neurotoxins are the molecules which block the transmission of the nerve impulse. The marine neurotoxins are widely seen in marine worms, sea anemone, cone snails. Neurotoxins act on nerve terminals and block the transmission of the nerve impulse and are thus most poisonous to the prey and human. Some neurotoxins specifically target ion channels, and different receptors. The structures and the various properties were annotated from PubChem and ChemSpider. The user can retrieve the details of neurotoxin, about its source, structure, its target, and the pharmacokinetics studies. The ADME and toxicology property of the marine neurotoxins was predicted using ADMETOX box. It was found that most of the marine neurotoxins were peptide molecules. It was observed that many marine neurotoxins had the potency to treat various diseases like Alzheimer's, Parkinson's, epilepsy, certain types of cancer and associated pain relief. 148 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Tradicionalmente, los fármacos se descubrían probando los compuestos sintetizados en procesos de varios pasos, que consumían mucho tiempo, contra una batería de pantallas biológicas in vivo. A continuación, los compuestos prometedores se estudiaban más a fondo en su desarrollo, donde se investigaban sus propiedades farmacéuticas, su metabolismo y su posible toxicidad. Aquí presentamos un estudio sobre los compuestos principales a base de plantas y su potencial afinidad de unión a las moléculas efectoras de enfermedades importantes como el cáncer de endometrio. Los estudios clínicos demuestran una correlación positiva entre el grado de PDK1 y la progresión maligna de las lesiones precancerosas en el endometrio. Por lo tanto, la identificación de un inhibidor eficaz y bien tolerado contra el cáncer representa una estrategia racional de quimioprevención. En este estudio se han investigado los efectos de los compuestos de origen natural que inhiben la diana. Nuestros resultados revelan que estos compuestos utilizan menos energía para unirse a la diana e inhibir su actividad que los fármacos comerciales utilizados. Su alta actividad de unión a la diana introduce la perspectiva de su uso en aplicaciones quimiopreventivas, además de que son compuestos naturales de libre acceso que pueden utilizarse de forma segura para prevenir enfermedades. 116 pp. Spanisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Traditionally, drugs were discovered by testing compounds synthesized in time consuming multi-step processes against a battery of in vivo biological screens. Promising compounds were then further studied in development, where their pharmaceutical properties, metabolism and potential toxicity were investigated. Here we present a study on herbal lead compounds and their potential binding affinity to the effectors molecules of major diseases like endometrial cancer. Clinical studies demonstrate a positive correlation between the extent of PDK1 and malignant progression of pre cancerous lesions in endometrial. Therefore, identification of effective, well-tolerated anti cancer inhibitor represents a rational chemo preventive strategy. This study has investigated the effects of naturally occurring compounds that inhibits the target. Our results reveal that these compounds use less energy to bind to the target and inhibit its activity than the commercial drugs used. Their high legend binding activity to the target introduce the prospect for their use in chemo preventive applications in addition they are freely available natural compounds that can be safely used to prevent disease.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: R.M JayadeepaJayadeepa.R.M, M.Sc: Studied Bioinformatics at Dr.G.R.Damodaran College of Science,Coimbatore,Tamilnadu,India Research Scientist at Institute Of Computational Biology,Bangalore,India Areas of Interest : Insilico Drug D.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The toxins has a wonderful characteristics & medicinal values from marine sources which can be handy for researchers working on neuro-degenerative diseases.Neurotoxins are the molecules which block the transmission of the nerve impulse. The marine neurotoxins are widely seen in marine worms, sea anemone, cone snails. Neurotoxins act on nerve terminals and block the transmission of the nerve impulse and are thus most poisonous to the prey and human. Some neurotoxins specifically target ion channels, and different receptors. The structures and the various properties were annotated from PubChem and ChemSpider. The user can retrieve the details of neurotoxin, about its source, structure, its target, and the pharmacokinetics studies. The ADME and toxicology property of the marine neurotoxins was predicted using ADMETOX box. It was found that most of the marine neurotoxins were peptide molecules. It was observed that many marine neurotoxins had the potency to treat various diseases like Alzheimer's, Parkinson's, epilepsy, certain types of cancer and associated pain relief.…

Kartoniert / Broschiert. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: R.M JayadeepaJayadeepa.R.M, M.Sc: Studied Bioinformatics at Dr.G.R.Damodaran College of Science,Coimbatore,Tamilnadu,India Research Scientist at Institute Of Computational Biology,Bangalore,India Areas of Interest : Insilico Drug De.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: R.M JayadeepaJayadeepa.R.M, M.Sc: Studied Bioinformatics at Dr.G.R.Damodaran College of Science,Coimbatore,Tamilnadu,India Research Scientist at Institute Of Computational Biology,Bangalore,India Areas of Interest : Insilico Drug.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Traditionally, drugs were discovered by testing compounds synthesized in time consuming multi-step processes against a battery of in vivo biological screens. Promising compounds were then further studied in development, where their pharmaceutical properties, metabolism and potential toxicity were investigated. Here we present a study on herbal lead compounds and their potential binding affinity to the effectors molecules of major diseases like endometrial cancer. Clinical studies demonstrate a positive correlation between the extent of PDK1 and malignant progression of pre cancerous lesions in endometrial. Therefore, identification of effective, well-tolerated anti cancer inhibitor represents a rational chemo preventive strategy. This study has investigated the effects of naturally occurring compounds that inhibits the target. Our results reveal that these compounds use less energy to bind to the target and inhibit its activity than the commercial drugs used. Their high legend binding activity to the target introduce the prospect for their use in chemo preventive applications in addition they are freely available natural compounds that can be safely used to prevent disease.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 116 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Traditionnellement, les médicaments étaient découverts en testant des composés synthétisés par des processus à étapes multiples et longs contre une batterie d'écrans biologiques in vivo. Les composés prometteurs étaient ensuite étudiés plus en détail en cours de développement, où leurs propriétés pharmaceutiques, leur métabolisme et leur toxicité potentielle étaient étudiés. Nous présentons ici une étude sur les composés de plomb à base de plantes et leur affinité potentielle de liaison avec les molécules effectrices de maladies majeures comme le cancer de l'endomètre. Les études cliniques démontrent une corrélation positive entre l'étendue de la PDK1 et la progression maligne des lésions précancéreuses de l'endomètre. Par conséquent, l'identification d'un inhibiteur anticancéreux efficace et bien toléré représente une stratégie rationnelle de chimioprévention. Cette étude a examiné les effets des composés naturels qui inhibent la cible. Nos résultats révèlent que ces composés utilisent moins d'énergie pour se lier à la cible et inhiber son activité que les médicaments commerciaux utilisés. Leur forte activité de liaison à la cible ouvre la perspective de leur utilisation dans des applications de chimioprévention. En outre, il s'agit de composés naturels librement disponibles qui peuvent être utilisés en toute sécurité pour prévenir les maladies. 120 pp. Französisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The toxins has a wonderful characteristics & medicinal values from marine sources which can be handy for researchers working on neuro-degenerative diseases.Neurotoxins are the molecules which block the transmission of the nerve impulse. The marine neurotoxins are widely seen in marine worms, sea anemone, cone snails. Neurotoxins act on nerve terminals and block the transmission of the nerve impulse and are thus most poisonous to the prey and human. Some neurotoxins specifically target ion channels, and different receptors. The structures and the various properties were annotated from PubChem and ChemSpider. The user can retrieve the details of neurotoxin, about its source, structure, its target, and the pharmacokinetics studies. The ADME and toxicology property of the marine neurotoxins was predicted using ADMETOX box. It was found that most of the marine neurotoxins were peptide molecules. It was observed that many marine neurotoxins had the potency to treat various diseases like Alzheimer's, Parkinson's, epilepsy, certain types of cancer and associated pain relief.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 148 pp. Englisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Tradicionalmente, los fármacos se descubrían probando los compuestos sintetizados en procesos de varios pasos, que consumían mucho tiempo, contra una batería de pantallas biológicas in vivo. A continuación, los compuestos prometedores se estudiaban más a fondo en su desarrollo, donde se investigaban sus propiedades farmacéuticas, su metabolismo y su posible toxicidad. Aquí presentamos un estudio sobre los compuestos principales a base de plantas y su potencial afinidad de unión a las moléculas efectoras de enfermedades importantes como el cáncer de endometrio. Los estudios clínicos demuestran una correlación positiva entre el grado de PDK1 y la progresión maligna de las lesiones precancerosas en el endometrio. Por lo tanto, la identificación de un inhibidor eficaz y bien tolerado contra el cáncer representa una estrategia racional de quimioprevención. En este estudio se han investigado los efectos de los compuestos de origen natural que inhiben la diana. Nuestros resultados revelan que estos compuestos utilizan menos energía para unirse a la diana e inhibir su actividad que los fármacos comerciales utilizados. Su alta actividad de unión a la diana introduce la perspectiva de su uso en aplicaciones quimiopreventivas, además de que son compuestos naturales de libre acceso que pueden utilizarse de forma segura para prevenir enfermedades. …

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Tradicionalmente, los fármacos se descubrían probando los compuestos sintetizados en procesos de varios pasos, que consumían mucho tiempo, contra una batería de pantallas biológicas in vivo. A continuación, los compuestos prometedores se estudiaban más a fondo en su desarrollo, donde se investigaban sus propiedades farmacéuticas, su metabolismo y su posible toxicidad. Aquí presentamos un estudio sobre los compuestos principales a base de plantas y su potencial afinidad de unión a las moléculas efectoras de enfermedades importantes como el cáncer de endometrio. Los estudios clínicos demuestran una correlación positiva entre el grado de PDK1 y la progresión maligna de las lesiones precancerosas en el endometrio. Por lo tanto, la identificación de un inhibidor eficaz y bien tolerado contra el cáncer representa una estrategia racional de quimioprevención. En este estudio se han investigado los efectos de los compuestos de origen natural que inhiben la diana. Nuestros resultados revelan que estos compuestos utilizan menos energía para unirse a la diana e inhibir su actividad que los fármacos comerciales utilizados. Su alta actividad de unión a la diana introduce la perspectiva de su uso en aplicaciones quimiopreventivas, además de que son compuestos naturales de libre acceso que pueden utilizarse de forma segura para prevenir enfermedades.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 116 pp. Spanisch.…

Taschenbuch. Condizione: Neu. Cáncer de endometrio no revelado | Enfoque insilico de descubrimiento de fármacos en el cáncer de endometrio | Jayadeepa R. M | Taschenbuch | Spanisch | 2021 | Ediciones Nuestro Conocimiento | EAN 9786203292565 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand. …

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Traditioneel werden geneesmiddelen ontdekt door verbindingen die in tijdrovende meerstapsprocessen waren gesynthetiseerd, te toetsen aan een reeks in vivo biologische tests. Veelbelovende verbindingen werden dan verder bestudeerd in de ontwikkelingsfase, waar hun farmaceutische eigenschappen, metabolisme en potentiële toxiciteit werden onderzocht. Hier presenteren wij een studie van de lead-verbindingen uit kruiden en hun potentiële bindingsaffiniteit met de effectormoleculen van belangrijke ziekten zoals endometriumkanker. Klinische studies tonen een positieve correlatie aan tussen de mate van PDK1 en kwaadaardige progressie van prekankervormige laesies in het endometrium. Daarom is de identificatie van een effectieve, goed verdraagbare anti-kanker remmer een rationele chemo-preventieve strategie. Deze studie heeft de effecten onderzocht van natuurlijk voorkomende verbindingen die het doelwit remmen. Onze resultaten tonen aan dat deze verbindingen minder energie gebruiken om zich aan het doelwit te binden en de activiteit ervan te remmen dan de gebruikte commerciële geneesmiddelen. Hun hoge bindingsactiviteit met het doelwit opent perspectieven voor hun gebruik in chemopreventieve toepassingen. Bovendien zijn het vrij verkrijgbare natuurlijke verbindingen die veilig kunnen worden gebruikt om ziekten te voorkomen. 120 pp. Niederländisch.…