robert n eisenman (34 risultati)

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Taschenbuch. Condizione: Neu. The Myc/Max/Mad Transcription Factor Network | Robert N. Eisenman | Taschenbuch | Current Topics in Microbiology and Immunology | vii | Englisch | 2014 | Springer | EAN 9783642421419 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.

Condizione: Gut. Zustand: Gut | Seiten: 300 | Sprache: Englisch | Produktart: Bücher | Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the ¿big picture¿ and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.

Buch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.

Condizione: Sehr gut. Zustand: Sehr gut | Seiten: 300 | Sprache: Englisch | Produktart: Bücher | Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the ¿big picture¿ and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli?cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms.

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5 vol.: vol. 1: 57 pp. ; vol. 2: 58 pp. ; vol. 3: 42 pp.; vol. 4: 66 pp. ; vol. 5: 50 pp.; 5 vol.: 23.2 x 14.6 cm. (each); glue bound; black-and-white; edition size unknown; unsigned and unnumbered; offset-printed Volumes I-V of "Summary of a Workshop," a biannual series of symposiums on contemporary art sponsored by the Frederick R. Weisman Foundation and held at various North American locations. Each symposium was accompanied by a catalogue which summarized the conversations that took place. Volume I: "The Relationship Between Art and Architecture," held in Santa Monica, CA, January 21-22, 1989. Participants included: Frank O. Gehry, Daniel Buren, Jean-Louis Cohen, Cesar Pelli, Donald Judd, Irving Lavin, Germano Celant, Henry N. Cobb, Christopher Knight, Mildred Friedman, John Chamberlain, Peter Eisenman, Robert Irwin, Michael Graves, Nancy Wexler, Henry T. Hopkins, and Michael Rotondi. Volume II: "Art + Architecture + Society," held in Toronto, Canada, July 22-23, 1989. Participants included: Henry T. Hopkins, Michael Rotondi, Diana Agrest, Lynda Benglis, Scott Burton, Adele Freedman, April Greiman, Alanna Heiss, Craig Hodgetts, Walter Hopps, Catherine Ingraham, Eric Owen Moss, Matt Mullican, Larry Richards, David Ross, Alexis Smith, and Leon Whiteson. Volume III, "Art Fairs : Plans and Process," held in Los Angeles, CA, December 5-6, 1989. Participants included: O. Kelley Anderson Jr., Brian Angel, Dr. Alberto Anfossi, Rosina Gómez Baeza, Dr. Emil Bammatter, Thomas P. Blackman, Van Deren Coke, Michelle De Angelus, Milton Esterow, Anita Kaegi, Claudio Bruni Sakraischik, Allan Schwartzman, Leif Ståhle, Tamara Thomas, Robert Thomson. Volume IV, "Conservation and Contemporary Art," held in Richmond, VA, June 4-5, 1990. Participants included: Henry T. Hopkins, Billie Milam, Albert Albano, James Bernstein, Sharon Blank, Victoria Blyth Hill, Tom Branchick, William Leischer, Carol Mancusi-Ungaro, Ross Merill, Roy De Forest, Tim Ebner, George Herms, Duane Hanson, Rotraut Klein-Moquay, Ida Kohlmeyer, Miriam Shapiro, Paul Brach, Zora Sweet Pinney, and Nora Halpern Brougher. Volume V, "Support for the Arts in Unsupportive Times," held in Los Angeles, CA, December 4-5, 1990. Participants included: Nora Halpern Brougher, Henry T. Hopkins, Cee Scott Brown, Marie Cieri, Pamela Clapp, Gary Garrels, Stanley Grinstein, David Ireland, Steven D. Lavine, Bella Lewitzky, Lisa Lyons, Anne MacDonald, Peter Norton, Max Palevsky, Claire Peeps, Dr. Thomas Reese, Joy Silverman, Tina Summerlin, Ella King Torrey, Joel Wachs, and Frederick R. Weisman. "Twice each year the Frederick R. Weisman Art Foundation conducts workshops dealing with issues of importance to those involved in the creation, exposition, collection, conservation and education of international contemporary art in all of its manifestations. These workshops bring together approximately eighteen experts in closed session for two days. The topic is determined by the Foundation but the direction that conversation takes is determined by the participants. There is no agenda. The workshops are taped, transcribed, edited, published in the present form and distributed to participants, interested parties, museums and libraries." -- Henry T. Hopkins, director. Very Good / Fine. Set of 5 volumes. Light rubbing and yellowing of cover edges and light yellowing of pages, otherwise Fine. Contents clean and unmarked.

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms. 296 pp. Englisch.

Buch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scientists often look askance at their colleagues whose research appears too strongly focused on a single gene or gene product. We are supposed to be interested in the 'big picture' and excessive zeal in pursuit of a single pixel might seem to border on an obsession that is likely to yield only details. However as this volume of Current Topics in Microbiology and Immunology demonstrates, this is certainly not the case for myc. Intense study of this en- matic proto-oncogene over the last twenty years has only broadened our view of its functions and led to insights into mechanisms relating to transcriptional regulation as well as to cell growth, proliferation, differentiation, apoptosis and organismal development. The myc gene originally came to light as a retroviral oncogene (v-myc) associated with a wide range of acute neoplasms. It was later shown to be a virally transduced cellular gene (c-myc) which is a member of family of on- genes (c-myc,N-myc,L-myc). These family members are themselves subject to a bewildering assortment of genetic rearrangements associated with many different types of tumors derived from many different types of cells. These rearrangements (including chromosomal translocation, viral integration, and gene ampli cation) act to uncouple expression of the myc family genes from their normal physiological regulators. The chapter by LIU and LEVENS - scribes the key pathways leading to regulation of myc expression, showing that such regulation occurs at several different levels and through multiple mechanisms. 300 pp. Englisch.