Sopjani mentor (55 risultati)

Condizione: New.

Condizione: New. In English.

Condizione: New.

Taschenbuch. Condizione: Neu. AMPK in the regulation of autophagy, cancers and cellular transport | Discussions, Conclusions and Perspectives | Mentor Sopjani | Taschenbuch | 76 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659593345 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Taschenbuch. Condizione: Neu. Relevance of the aging suppressor protein Klotho in health and disease | Introduction, Cellular Signaling, Mechanisms, Clinical Relevance, Conclusions and Perspectives | Mentor Sopjani | Taschenbuch | 64 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659506246 | Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, 66111 Saarbrücken, info[at]akademikerverlag[dot]de | Anbieter: preigu.…

Paperback. Condizione: Brand New. 120 pages. 8.66x5.91x0.28 inches. In Stock.

Taschenbuch. Condizione: Neu. Suicidal erythrocytes death induced by gold and by cadmium ions | Significance of eryptosis | Mentor Sopjani | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639333855 | Verantwortliche Person für die EU: VDM Verlag Dr. Müller, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu. …

Taschenbuch. Condizione: Neu. The AMPK in the regulation of eryptosis and Na+ coupled transporters | Regulation, methods and discussion | Mentor Sopjani | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639258295 | Verantwortliche Person für die EU: VDM Verlag Dr. Müller, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

PF. Condizione: New. This item is printed on demand. Brand new book, sourced directly from publisher. Dispatch time is 6-7 days from our warehouse. Book will be sent in robust, secure packaging to ensure it reaches you securely.

PAP. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condizione: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The nutrient and energy sensor AMP-activated protein Kinase regulates cellular and whole-body energy homeostasis through stimulating catabolic ATP-generating and suppressing anabolic ATP-consuming pathways thereby helping cells survive during energy starvation. AMPK plays an important role in autophagy induction in response to starvation, a process that involves phosphorylating TSC2 and mTOR activation. Recent advances indicate the kinase also to exert tumor suppressor activity by stimulating apoptosis, autophagy and cell growth and proliferation. AMPK can be used to protect from metabolic syndrome. This kinase has previously been demonstrated to be either directly or indirectly involved in the regulation of numerous carriers, channels and pumps of high relevance for cellular physiology and pathophysiology. Thus, AMPK provides a necessary link between cellular energy metabolism and cellular transport activity. Better understanding of the AMPK role in the regulation of cell transport under physiological and pathological conditions may represent a potential for developing therapies for many human diseases and disorders, especially cancers. 76 pp. Englisch.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Klotho protein is known to be involved in premature aging as an aging suppressor. Overexpression of the Klotho gene extends lifespan in mice and defective Klotho results in rapid aging and early death. Both the membrane and secreted forms of Klotho have biological activity. Klotho serves as a co-receptor for fibroblast growth factor (FGF), but it also functions as a humoral factor that regulates cell survival and proliferation, vitamin D metabolism, cardiac remodeling progresses to heart failure, and calcium and phosphate homeostasis that correlates with its affect on aging and may serve as a key factor in cancer development with potential tumor suppressor effect. Moreover, Klotho protects against several pathogenic processes in a FGF23-independent manner. These processes include cancer metastasis, vascular calcification, and renal fibrosis. This book covers the recent advances in Klotho research and discusses novel klotho-dependent mechanisms that are clinically relevant in aging and age-related diseases as well as the particular role of Klotho as a target for potential therapeutics. 64 pp. Englisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The nutrient and energy sensor AMP-activated protein Kinase regulates cellular and whole-body energy homeostasis through stimulating catabolic ATP-generating and suppressing anabolic ATP-consuming pathways thereby helping cells survive during energy starvation. AMPK plays an important role in autophagy induction in response to starvation, a process that involves phosphorylating TSC2 and mTOR activation. Recent advances indicate the kinase also to exert tumor suppressor activity by stimulating apoptosis, autophagy and cell growth and proliferation. AMPK can be used to protect from metabolic syndrome. This kinase has previously been demonstrated to be either directly or indirectly involved in the regulation of numerous carriers, channels and pumps of high relevance for cellular physiology and pathophysiology. Thus, AMPK provides a necessary link between cellular energy metabolism and cellular transport activity. Better understanding of the AMPK role in the regulation of cell transport under physiological and pathological conditions may represent a potential for developing therapies for many human diseases and disorders, especially cancers.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The Klotho protein is known to be involved in premature aging as an aging suppressor. Overexpression of the Klotho gene extends lifespan in mice and defective Klotho results in rapid aging and early death. Both the membrane and secreted forms of Klotho have biological activity. Klotho serves as a co-receptor for fibroblast growth factor (FGF), but it also functions as a humoral factor that regulates cell survival and proliferation, vitamin D metabolism, cardiac remodeling progresses to heart failure, and calcium and phosphate homeostasis that correlates with its affect on aging and may serve as a key factor in cancer development with potential tumor suppressor effect. Moreover, Klotho protects against several pathogenic processes in a FGF23-independent manner. These processes include cancer metastasis, vascular calcification, and renal fibrosis. This book covers the recent advances in Klotho research and discusses novel klotho-dependent mechanisms that are clinically relevant in aging and age-related diseases as well as the particular role of Klotho as a target for potential therapeutics. …

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sopjani MentorDr.rer.nat. Mentor Sopjani, is a biologist and an expert in molecular biology of the cell as well as molecular physiology. His main research interest is focused in defining molecular mechanisms of suicidal erythrocyte d.…

Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sopjani MentorDr.rer.nat. Mentor Sopjani, is a biologist and an expert in molecular biology of the cell as well as molecular physiology. His main research interest is focused in defining molecular mechanisms of suicidal erythrocyte d.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 64 pp. Spanisch.

Kartoniert / Broschiert. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sopjani MentorDr.rer.nat. Mentor Sopjani, is a biologist and an expert in suicidal erythrocyte death or eryptosis as well as in electrophysiology. Dr. Sopjani received his PhD from the University of Tuebingen, Germany. He is assistant. …

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The suicidal death of erythrocytes, eryptosis, is characterized by cell shrinkage and cell membrane scrambling leading to phosphatidylserine exposure at the RBCs surface. As macrophages are equipped with phosphatidylserine receptors, they bind, engulf and degrade phosphatidylserine exposing cells; thereby RBCs are rapidly cleared from circulating blood. RBCs cell membrane scrambling is stimulated by increase of cytosolic Ca2+ concentration ([Ca2+](i)) and formation of ceramide. Ca2+ entry and/or ceramide formation and thus eryptosis are triggered by many pollutants. The present study explored whether eryptosis could be similarly triggered by exposure to gold, and to cadmium. To this end, RBCs from healthy volunteers were exposed to AuCl and to cadmium ions (Cd(2+)) and phosphatidylserine exposure (annexin V binding), cell volume (forward scatter), [Ca2+](i) (Fluo3-dependent fluorescence), and ceramide formation (anti-ceramide-FITC fluorescence) were determined by flow cytometry. The present observations underlie the mechanism of action of cadmium ions, and disclose a novel action of gold, which may well contribute to side effects during treatment with gold preparations.…

Kartoniert / Broschiert. Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sopjani MentorDr.rer.nat. Mentor Sopjani, is a biologist and an expert in suicidal erythrocyte death or eryptosis as well as in electrophysiology. Dr. Sopjani received his Ph.D. from the University of Tuebingen, Germany. He is a postd. …

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The Klotho protein is known to be involved in premature aging as an aging suppressor. Overexpression of the Klotho gene extends lifespan in mice and defective Klotho results in rapid aging and early death. Both the membrane and secreted forms of Klotho have biological activity. Klotho serves as a co-receptor for fibroblast growth factor (FGF), but it also functions as a humoral factor that regulates cell survival and proliferation, vitamin D metabolism, cardiac remodeling progresses to heart failure, and calcium and phosphate homeostasis that correlates with its affect on aging and may serve as a key factor in cancer development with potential tumor suppressor effect. Moreover, Klotho protects against several pathogenic processes in a FGF23-independent manner. These processes include cancer metastasis, vascular calcification, and renal fibrosis. This book covers the recent advances in Klotho research and discusses novel klotho-dependent mechanisms that are clinically relevant in aging and age-related diseases as well as the particular role of Klotho as a target for potential therapeutics.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 64 pp. Englisch. …

Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The nutrient and energy sensor AMP-activated protein Kinase regulates cellular and whole-body energy homeostasis through stimulating catabolic ATP-generating and suppressing anabolic ATP-consuming pathways thereby helping cells survive during energy starvation. AMPK plays an important role in autophagy induction in response to starvation, a process that involves phosphorylating TSC2 and mTOR activation. Recent advances indicate the kinase also to exert tumor suppressor activity by stimulating apoptosis, autophagy and cell growth and proliferation. AMPK can be used to protect from metabolic syndrome. This kinase has previously been demonstrated to be either directly or indirectly involved in the regulation of numerous carriers, channels and pumps of high relevance for cellular physiology and pathophysiology. Thus, AMPK provides a necessary link between cellular energy metabolism and cellular transport activity. Better understanding of the AMPK role in the regulation of cell transport under physiological and pathological conditions may represent a potential for developing therapies for many human diseases and disorders, especially cancers.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 76 pp. Englisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The AMP-activated protein kinase (AMPK) is a trimeric enzyme that induces a cascade of events within cells in response to the ever changing energy charge of the cell and thus plays a central control role in maintaining energy homeostasis. AMPK appear to play roles in upregulation of energy-producing while downregulates energy-utilizing mechanisms thus support cell survival during energy deprivation. Any metabolic stress that inhibits ATP production, or that accelerates ATP consumption, will tend to increase the AMP:ATP ratio thus activate AMPK. Similar to nucleated cell survival, erythrocyte survival could be limited by suicidal erythrocyte death or eryptosis. Since a very little academic literature exists about eryptosis, this book provides the mechanism of action of AMPK in eryptosis and help understanding the overall eryptosis process in detail. Furthermore, the book explains the role and regulation of Na+-coupled transporters (focused in SGLT1, and EAAT3 & EAAT4) by AMPK. The book also introduces detail methods coupled this investigation and should be especially useful to professionals in cell biology, physiology and molecular biology, or others interested in this topic.…

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware 64 pp. Französisch.

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - La proteína quinasa activada por AMP (AMPK), que actúa como sensor de nutrientes y energía, regula la homeostasis energética celular y de todo el organismo mediante la estimulación de las vías catabólicas generadoras de ATP y la supresión de las vías anabólicas consumidoras de ATP, lo que ayuda a las células a sobrevivir durante la privación energética. La AMPK desempeña un papel importante en la inducción de la autofagia en respuesta a la privación de nutrientes, un proceso que implica la fosforilación de TSC2 y la activación de mTOR. Avances recientes indican que esta quinasa también ejerce actividad supresora de tumores al estimular la apoptosis, la autofagia y el crecimiento y la proliferación celular. La AMPK puede utilizarse para proteger contra el síndrome metabólico. Se ha demostrado anteriormente que esta quinasa participa, ya sea directa o indirectamente, en la regulación de numerosos transportadores, canales y bombas de gran relevancia para la fisiología y la fisiopatología celular. Así, la AMPK proporciona un vínculo necesario entre el metabolismo energético celular y la actividad de transporte celular. Una mejor comprensión del papel de la AMPK en la regulación del transporte celular en condiciones fisiológicas y patológicas puede representar un potencial para el desarrollo de terapias para numerosas enfermedades y trastornos humanos, especialmente los cánceres.…

PAP. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condizione: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.