Sowunmi kehinde (20 risultati)

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  • Lingua: Inglese

    Editore: GRIN Verlag, 2020

    3346120112 / 9783346120113

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    Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

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    Condizione: Nuovo

    EUR 17,95

    EUR 60,26 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Academic Paper from the year 2020 in the subject Biology - Genetics / Gene Technology, grade: 14.0, University of Lagos (University of Lagos), course: Cell Biology and Genetics, language: English, abstract: A huge number of genes within the human genome code are proteins that mediate and/or control genetics processes. Although a large body of information on the number of genes, on chromosomal localisation, gene structure and function has been gathered, we are far from understanding the orchestrated way of how they make metabolism. Nevertheless, based on the genetic information emerging on a daily basis, we are offered fantastic new tools that allow us new insights into the molecular basis of human metabolism under normal as well as pathophysiological conditions. Recent technological advancements have made it possible to analyse simultaneously large sets of mRNA and/or proteins expressed in a biological sample or to define genetic heterogeneity that may be important for the individual response of an organism to changes in its nutritional environment. Applications of the new techniques of genome and proteome analysis are central for the development of nutritional sciences in the next decade and its integration into the rapidly developing era of functional genomics.The proteome is the entire set of proteins that are produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefitted greatly from the genetic information of the Human Genome Project; it also covers emerging scientific research and the exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry. After genomics and transcriptomics, proteomics is the next step in the study of biological systems. It is more complicated than genomics because an organism's genome is more or less constant, whereas the proteome differs from cell to cell and from time to time. Distinct genes are expressed in different cell types, which means that even the basic set of proteins that are produced in a cell needs to be identified.…

  • Lingua: Inglese

    Editore: GRIN Verlag, 2020

    3346206017 / 9783346206015

    • Brossura

    Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 17,95

    EUR 60,31 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Academic Paper from the year 2020 in the subject Biology - Genetics / Gene Technology, grade: 9.0, , course: Cell Biology and Genetics, language: English, abstract: Nucleic acids have proven to be viable targets for small molecule drugs. While many examples of such drugs are detailed in the literature, only a select few have found practical use in a clinical setting. These currently employed nucleic acid targeting therapies suffer from either debilitating off-target side effects or succumb to a resistance mechanism of the target. The need for new small molecules that target nucleic acids is evident.However, designing a novel drug to bind to DNA or RNA requires a detailed understanding of exactly what binding environments each nucleic acid presents. In an effort to broaden this knowledge, the work presented in this thesis details the binding location and affinity of known and novel nucleic acid binding small molecules with targets ranging from simple RNA secondary structure all the way to the complex structure of ribosomal RNA. Specifically, it is shown that the anthracycline classes of antineoplastics prefer to bind at or near mismatch base pairs in both physiologically relevant iron responsive element RNA hairpin constructs as well as DNA hairpin constructs presenting mismatched base pairs.Also characterized in this thesis is a novel class of topoisomerase II / histone deacetylase inhibitor conjugates that display a unique affinity for DNA over RNA. Finally, the novel class of macrolide-peptide conjugates, known as peptolides, is shown to retain potent translation inhibition of the prokaryotic ribosome and identification of a novel binding site for the anthracycline class of drugs and the characterization of the two novel drug designs presented in this thesis will undoubtedly aid in the effort to design and discover new molecules that aim for nucleic acid targets.…

  • Lingua: Inglese

    Editore: GRIN Verlag, 2019

    3346084264 / 9783346084262

    • Brossura

    Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 17,95

    EUR 60,28 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Seminar paper from the year 2019 in the subject Biology - Genetics / Gene Technology, , course: Cell Biology and Genetics, language: English, abstract: Proteome is the entire set of proteins encoded by the genome and proteomics is the discipline which studies the global set of proteins, their expression, function and structure. Knowledge of proteins is thus crucial in understanding the mechanism of any biological process. Although advances in genome sequencing have allowed the identification of a number of open reading frames (ORFs), but this information is far from complete. On an average, about 40% of the gene sequences detected in the genomic databases code for proteins of hypothetical or unknown function.…

  • Lingua: Inglese

    Editore: GRIN Verlag, 2020

    3346087794 / 9783346087799

    • Brossura

    Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 17,95

    EUR 60,34 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Research Paper (postgraduate) from the year 2019 in the subject Biology - Cytology, grade: 5.0, University of Lagos (University of Lagos), course: Cell Biology and Genetics, language: English, abstract: This work examines the impact of the medical plants Nigella sativa, Carica papaya and Boswellia sacra with the help of an experiment conducted with fifty female albino mice.Nigella sativa, Carica papaya and Boswellia sacra are medicinal plants in the commonly used in folkloric medicine due to the presence of its immense therapeutic properties. Fifty (50) female albino mice weighing between 15-22g were divided into five groups of 10 mice each. Animal in group 1 served as control group and were administered distilled water while animal in group 2 were given 2ml of cisplatin (orally). Animal in group 3-5 were given orally; 100 mg/kg (low dose), 200 mg/kg (medium dose) and 400 mg/kg (high dose) of triherbal preparation. The feeding regimens lasted for 28 days. After 28 days, mammary gland and blood samples were collected for haematological and antioxidant analysis.The triherbal formula decreased the GSH and MDA levels of mice treated with 100 mg/kg and 400 mg/kg doses compare to control. The measurement of total protein content, SOD and CAT increased in treated animals compared to control. However, RBC (Red Blood Cell) counts significantly decreased in the low, medium and high dose groups (0.95±0.08, 6.57±0.08 and 3.55±0.55 x 106 cells/mm3 respectively) compared to control (7.34±0.40) at P<0.05. Also, significant decreases (P<0.05) in the level of the total WBC (White Blood Cell) count, platelet count, PCV (Packed Cell Volume) and Hb (haemoglobin) concentration were observed. The decreases were dose dependent. The MCH (Mean Corpuscular Haemoglobin) and MCHC (Mean Corpuscular Haemoglobin Concentration) except MCV (Mean Corpuscular Volume) significantly decreased in treated group only. The triherbal formulation exhibited significant antioxidant activities showing increased levels of SOD, CAT and Protein content due to activation of the enzyme involve in detoxification of free radicals and decreased in the level of GSH and MDA due to accumulation of peroxides and H2O2. Also, decreased in haematological parameters due to the presence of phytochemicals such as phenol, resins, saponins, sterols, tannis and terpenes in the triherbal formula.Therefore, it has potential to induce haematotoxicity hence consumption of high concentrations should be discouraged.…

  • Lingua: Inglese

    Editore: GRIN Verlag, 2020

    3346075710 / 9783346075710

    • Brossura

    Da: AHA-BUCH GmbH, Einbeck, GermaniaAHA-BUCH GmbH

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 42,95

    EUR 60,56 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. Druck auf Anfrage Neuware - Printed after ordering - Research Paper (undergraduate) from the year 2014 in the subject Biology - Diseases, Health, Nutrition, Tai Solarin University of Education, course: Biology, language: English, abstract: There seems to be epidemiological associations between quality of life and cognitive failure yet, studies determining the relationship between quality of life indices and cognitive failure have been sparse. In addition, no studies examining this relationship have been carried out in Nigerian population.To determine the association between quality of life indices and cognitive failure in a Nigerian sample.A cross-sectional study of 1,338 participants with diverse age groups, ethnicity and socioeconomic levels from three different States and regions in Nigeria recruited from eleven public hospitals between May 2014 and August 2014.Cognitive failure in relation to quality of life domains centring on physical and occupational functioning, perceptions about health status, psychological and social functioning were determined using linear and logistic regressions after adjusting for age, ethnicity, education, gender, marital status, family type, alcohol and smoking status.In the adjusted models, four of the indices for measuring quality of life domains were significantly associated with cognitive failures: worrying about health problems (adjusted odds ratio [AOR], 1.095; 95% CI, 1.05-1.14), health-related impairment in daily activities (AOR, 1.138; 95% CI, 1.09-1.93) and increased hospitalization (AOR, 1.55; 95% CI, 1.24-1.94) were associated with increased cognitive failures whereas showing care for one's health (AOR, 0.93; 95% CI, 0.89-0.96) was associated with decreased levels of cognitive failure. Linear regression analysis on these data recapitulated these results.Quality of life research appears to be vital for health needs assessment of populations and could have profound implications for cognitive failure and other health-related outcome assessment in biology, medicine and health services research.…

  • Lingua: Inglese

    Editore: GRIN Verlag Jul 2020, 2020

    3346206017 / 9783346206015

    • Brossura
    • Print on Demand

    Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 17,95

    EUR 23,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 2 disponibili

    Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Academic Paper from the year 2020 in the subject Biology - Genetics / Gene Technology, grade: 9.0, , course: Cell Biology and Genetics, language: English, abstract: Nucleic acids have proven to be viable targets for small molecule drugs. While many examples of such drugs are detailed in the literature, only a select few have found practical use in a clinical setting. These currently employed nucleic acid targeting therapies suffer from either debilitating off-target side effects or succumb to a resistance mechanism of the target. The need for new small molecules that target nucleic acids is evident.However, designing a novel drug to bind to DNA or RNA requires a detailed understanding of exactly what binding environments each nucleic acid presents. In an effort to broaden this knowledge, the work presented in this thesis details the binding location and affinity of known and novel nucleic acid binding small molecules with targets ranging from simple RNA secondary structure all the way to the complex structure of ribosomal RNA. Specifically, it is shown that the anthracycline classes of antineoplastics prefer to bind at or near mismatch base pairs in both physiologically relevant iron responsive element RNA hairpin constructs as well as DNA hairpin constructs presenting mismatched base pairs.Also characterized in this thesis is a novel class of topoisomerase II / histone deacetylase inhibitor conjugates that display a unique affinity for DNA over RNA. Finally, the novel class of macrolide-peptide conjugates, known as peptolides, is shown to retain potent translation inhibition of the prokaryotic ribosome and identification of a novel binding site for the anthracycline class of drugs and the characterization of the two novel drug designs presented in this thesis will undoubtedly aid in the effort to design and discover new molecules that aim for nucleic acid targets. 32 pp. Englisch.…

  • Lingua: Inglese

    Editore: GRIN Verlag Mär 2020, 2020

    3346120112 / 9783346120113

    • Brossura
    • Print on Demand

    Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 17,95

    EUR 23,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 2 disponibili

    Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Academic Paper from the year 2020 in the subject Biology - Genetics / Gene Technology, grade: 14.0, University of Lagos (University of Lagos), course: Cell Biology and Genetics, language: English, abstract: A huge number of genes within the human genome code are proteins that mediate and/or control genetics processes. Although a large body of information on the number of genes, on chromosomal localisation, gene structure and function has been gathered, we are far from understanding the orchestrated way of how they make metabolism. Nevertheless, based on the genetic information emerging on a daily basis, we are offered fantastic new tools that allow us new insights into the molecular basis of human metabolism under normal as well as pathophysiological conditions. Recent technological advancements have made it possible to analyse simultaneously large sets of mRNA and/or proteins expressed in a biological sample or to define genetic heterogeneity that may be important for the individual response of an organism to changes in its nutritional environment. Applications of the new techniques of genome and proteome analysis are central for the development of nutritional sciences in the next decade and its integration into the rapidly developing era of functional genomics.The proteome is the entire set of proteins that are produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefitted greatly from the genetic information of the Human Genome Project; it also covers emerging scientific research and the exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry. After genomics and transcriptomics, proteomics is the next step in the study of biological systems. It is more complicated than genomics because an organism's genome is more or less constant, whereas the proteome differs from cell to cell and from time to time. Distinct genes are expressed in different cell types, which means that even the basic set of proteins that are produced in a cell needs to be identified. 24 pp. Englisch. …

  • Lingua: Inglese

    Editore: GRIN Verlag Feb 2020, 2020

    3346087794 / 9783346087799

    • Brossura
    • Print on Demand

    Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

    Venditore con 5 stelle
    Contatta il venditore

    Condizione: Nuovo

    EUR 17,95

    EUR 23,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 2 disponibili

    Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research Paper (postgraduate) from the year 2019 in the subject Biology - Cytology, grade: 5.0, University of Lagos (University of Lagos), course: Cell Biology and Genetics, language: English, abstract: This work examines the impact of the medical plants Nigella sativa, Carica papaya and Boswellia sacra with the help of an experiment conducted with fifty female albino mice.Nigella sativa, Carica papaya and Boswellia sacra are medicinal plants in the commonly used in folkloric medicine due to the presence of its immense therapeutic properties. Fifty (50) female albino mice weighing between 15-22g were divided into five groups of 10 mice each. Animal in group 1 served as control group and were administered distilled water while animal in group 2 were given 2ml of cisplatin (orally). Animal in group 3-5 were given orally; 100 mg/kg (low dose), 200 mg/kg (medium dose) and 400 mg/kg (high dose) of triherbal preparation. The feeding regimens lasted for 28 days. After 28 days, mammary gland and blood samples were collected for haematological and antioxidant analysis.The triherbal formula decreased the GSH and MDA levels of mice treated with 100 mg/kg and 400 mg/kg doses compare to control. The measurement of total protein content, SOD and CAT increased in treated animals compared to control. However, RBC (Red Blood Cell) counts significantly decreased in the low, medium and high dose groups (0.95±0.08, 6.57±0.08 and 3.55±0.55 x 106 cells/mm3 respectively) compared to control (7.34±0.40) at P<0.05. Also, significant decreases (P<0.05) in the level of the total WBC (White Blood Cell) count, platelet count, PCV (Packed Cell Volume) and Hb (haemoglobin) concentration were observed. The decreases were dose dependent. The MCH (Mean Corpuscular Haemoglobin) and MCHC (Mean Corpuscular Haemoglobin Concentration) except MCV (Mean Corpuscular Volume) significantly decreased in treated group only. The triherbal formulation exhibited significant antioxidant activities showing increased levels of SOD, CAT and Protein content due to activation of the enzyme involve in detoxification of free radicals and decreased in the level of GSH and MDA due to accumulation of peroxides and H2O2. Also, decreased in haematological parameters due to the presence of phytochemicals such as phenol, resins, saponins, sterols, tannis and terpenes in the triherbal formula.Therefore, it has potential to induce haematotoxicity hence consumption of high concentrations should be discouraged. 36 pp. Englisch. …

  • Lingua: Inglese

    Editore: GRIN Verlag Dez 2019, 2019

    3346084264 / 9783346084262

    • Brossura
    • Print on Demand

    Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 17,95

    EUR 23,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 2 disponibili

    Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Seminar paper from the year 2019 in the subject Biology - Genetics / Gene Technology, , course: Cell Biology and Genetics, language: English, abstract: Proteome is the entire set of proteins encoded by the genome and proteomics is the discipline which studies the global set of proteins, their expression, function and structure. Knowledge of proteins is thus crucial in understanding the mechanism of any biological process. Although advances in genome sequencing have allowed the identification of a number of open reading frames (ORFs), but this information is far from complete. On an average, about 40% of the gene sequences detected in the genomic databases code for proteins of hypothetical or unknown function 28 pp. Englisch.…

  • Lingua: Inglese

    Editore: Grin Verlag, 2020

    3346206017 / 9783346206015

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    Da: Biblios, frankfurt am main, HESSE, GermaniaBiblios

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    Condizione: Nuovo

    EUR 41,26

    EUR 9,95 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 4 disponibili

    Condizione: New. PRINT ON DEMAND.

  • Lingua: Inglese

    Editore: GRIN Verlag Feb 2020, 2020

    3346075710 / 9783346075710

    • Brossura
    • Print on Demand

    Da: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, GermaniaBuchWeltWeit Ludwig Meier e.K.

    Venditore con 5 stelle
    Contatta il venditore

    Condizione: Nuovo

    EUR 42,95

    EUR 23,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 2 disponibili

    Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research Paper (undergraduate) from the year 2014 in the subject Biology - Diseases, Health, Nutrition, Tai Solarin University of Education, course: Biology, language: English, abstract: There seems to be epidemiological associations between quality of life and cognitive failure yet, studies determining the relationship between quality of life indices and cognitive failure have been sparse. In addition, no studies examining this relationship have been carried out in Nigerian population.To determine the association between quality of life indices and cognitive failure in a Nigerian sample.A cross-sectional study of 1,338 participants with diverse age groups, ethnicity and socioeconomic levels from three different States and regions in Nigeria recruited from eleven public hospitals between May 2014 and August 2014.Cognitive failure in relation to quality of life domains centring on physical and occupational functioning, perceptions about health status, psychological and social functioning were determined using linear and logistic regressions after adjusting for age, ethnicity, education, gender, marital status, family type, alcohol and smoking status.In the adjusted models, four of the indices for measuring quality of life domains were significantly associated with cognitive failures: worrying about health problems (adjusted odds ratio [AOR], 1.095; 95% CI, 1.05-1.14), health-related impairment in daily activities (AOR, 1.138; 95% CI, 1.09-1.93) and increased hospitalization (AOR, 1.55; 95% CI, 1.24-1.94) were associated with increased cognitive failures whereas showing care for one's health (AOR, 0.93; 95% CI, 0.89-0.96) was associated with decreased levels of cognitive failure. Linear regression analysis on these data recapitulated these results.Quality of life research appears to be vital for health needs assessment of populations and could have profound implications for cognitive failure and other health-related outcome assessment in biology, medicine and health services research. 68 pp. Englisch.…

  • Lingua: Inglese

    Editore: GRIN Verlag Feb 2020, 2020

    3346087794 / 9783346087799

    • Brossura
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    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000

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    Condizione: Nuovo

    EUR 17,95

    EUR 60,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Research Paper (postgraduate) from the year 2019 in the subject Biology - Cytology, grade: 5.0, University of Lagos (University of Lagos), course: Cell Biology and Genetics, language: English, abstract: This work examines the impact of the medical plants Nigella sativa, Carica papaya and Boswellia sacra with the help of an experiment conducted with fifty female albino mice.Nigella sativa, Carica papaya and Boswellia sacra are medicinal plants in the commonly used in folkloric medicine due to the presence of its immense therapeutic properties. Fifty (50) female albino mice weighing between 15-22g were divided into five groups of 10 mice each. Animal in group 1 served as control group and were administered distilled water while animal in group 2 were given 2ml of cisplatin (orally). Animal in group 3-5 were given orally; 100 mg/kg (low dose), 200 mg/kg (medium dose) and 400 mg/kg (high dose) of triherbal preparation. The feeding regimens lasted for 28 days. After 28 days, mammary gland and blood samples were collected for haematological and antioxidant analysis. The triherbal formula decreased the GSH and MDA levels of mice treated with 100 mg/kg and 400 mg/kg doses compare to control. The measurement of total protein content, SOD and CAT increased in treated animals compared to control. However, RBC (Red Blood Cell) counts significantly decreased in the low, medium and high dose groups (0.95±0.08, 6.57±0.08 and 3.55±0.55 x 106 cells/mm3 respectively) compared to control (7.34±0.40) at PGRIN Publishing GmbH, Waltherstraße 23, 80337 München 36 pp. Englisch. …

  • Lingua: Inglese

    Editore: GRIN Verlag Jul 2020, 2020

    3346206017 / 9783346206015

    • Brossura
    • Print on Demand

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000

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    Condizione: Nuovo

    EUR 17,95

    EUR 60,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Academic Paper from the year 2020 in the subject Biology - Genetics / Gene Technology, grade: 9.0, , course: Cell Biology and Genetics, language: English, abstract: Nucleic acids have proven to be viable targets for small molecule drugs. While many examples of such drugs are detailed in the literature, only a select few have found practical use in a clinical setting. These currently employed nucleic acid targeting therapies suffer from either debilitating off-target side effects or succumb to a resistance mechanism of the target. The need for new small molecules that target nucleic acids is evident.However, designing a novel drug to bind to DNA or RNA requires a detailed understanding of exactly what binding environments each nucleic acid presents. In an effort to broaden this knowledge, the work presented in this thesis details the binding location and affinity of known and novel nucleic acid binding small molecules with targets ranging from simple RNA secondary structure all the way to the complex structure of ribosomal RNA. Specifically, it is shown that the anthracycline classes of antineoplastics prefer to bind at or near mismatch base pairs in both physiologically relevant iron responsive element RNA hairpin constructs as well as DNA hairpin constructs presenting mismatched base pairs.Also characterized in this thesis is a novel class of topoisomerase II / histone deacetylase inhibitor conjugates that display a unique affinity for DNA over RNA. Finally, the novel class of macrolide-peptide conjugates, known as peptolides, is shown to retain potent translation inhibition of the prokaryotic ribosome and identification of a novel binding site for the anthracycline class of drugs and the characterization of the two novel drug designs presented in this thesis will undoubtedly aid in the effort to design and discover new molecules that aim for nucleic acid targets.GRIN Publishing GmbH, Waltherstraße 23, 80337 München 32 pp. Englisch.…

  • Lingua: Inglese

    Editore: GRIN Verlag Mär 2020, 2020

    3346120112 / 9783346120113

    • Brossura
    • Print on Demand

    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000

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    Condizione: Nuovo

    EUR 17,95

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    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Academic Paper from the year 2020 in the subject Biology - Genetics / Gene Technology, grade: 14.0, University of Lagos (University of Lagos), course: Cell Biology and Genetics, language: English, abstract: A huge number of genes within the human genome code are proteins that mediate and/or control genetics processes. Although a large body of information on the number of genes, on chromosomal localisation, gene structure and function has been gathered, we are far from understanding the orchestrated way of how they make metabolism. Nevertheless, based on the genetic information emerging on a daily basis, we are offered fantastic new tools that allow us new insights into the molecular basis of human metabolism under normal as well as pathophysiological conditions. Recent technological advancements have made it possible to analyse simultaneously large sets of mRNA and/or proteins expressed in a biological sample or to define genetic heterogeneity that may be important for the individual response of an organism to changes in its nutritional environment. Applications of the new techniques of genome and proteome analysis are central for the development of nutritional sciences in the next decade and its integration into the rapidly developing era of functional genomics.The proteome is the entire set of proteins that are produced or modified by an organism or system. This varies with time and distinct requirements, or stresses, that a cell or organism undergoes. Proteomics is an interdisciplinary domain that has benefitted greatly from the genetic information of the Human Genome Project; it also covers emerging scientific research and the exploration of proteomes from the overall level of intracellular protein composition, structure, and its own unique activity patterns. It is an important component of functional genomics.While proteomics generally refers to the large-scale experimental analysis of proteins, it is often specifically used for protein purification and mass spectrometry. After genomics and transcriptomics, proteomics is the next step in the study of biological systems. It is more complicated than genomics because an organism's genome is more or less constant, whereas the proteome differs from cell to cell and from time to time. Distinct genes are expressed in different cell types, which means that even the basic set of proteins that are produced in a cell needs to be identified.GRIN Publishing GmbH, Waltherstraße 23, 80337 München 24 pp. Englisch. …

  • Lingua: Inglese

    Editore: GRIN Verlag Dez 2019, 2019

    3346084264 / 9783346084262

    • Brossura
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    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000

    Venditore con 5 stelle
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    Condizione: Nuovo

    EUR 17,95

    EUR 60,00 spedizione 
    Spedito da Germania a U.S.A.

    Quantità: 1 disponibile

    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Seminar paper from the year 2019 in the subject Biology - Genetics / Gene Technology, , course: Cell Biology and Genetics, language: English, abstract: Proteome is the entire set of proteins encoded by the genome and proteomics is the discipline which studies the global set of proteins, their expression, function and structure. Knowledge of proteins is thus crucial in understanding the mechanism of any biological process. Although advances in genome sequencing have allowed the identification of a number of open reading frames (ORFs), but this information is far from complete. On an average, about 40% of the gene sequences detected in the genomic databases code for proteins of hypothetical or unknown functionGRIN Publishing GmbH, Waltherstraße 23, 80337 München 28 pp. Englisch.…

  • Lingua: Inglese

    Editore: GRIN Verlag, 2020

    3346120112 / 9783346120113

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    Taschenbuch. Condizione: Neu. Proteomics. Importance for the Future of Genetics Research | Kehinde Sowunmi | Taschenbuch | 24 S. | Englisch | 2020 | GRIN Verlag | EAN 9783346120113 | Verantwortliche Person für die EU: GRIN Publishing GmbH, Waltherstr. 23, 80337 München, info[at]grin[dot]com | Anbieter: preigu Print on Demand.…

  • Lingua: Inglese

    Editore: GRIN Verlag, 2020

    3346087794 / 9783346087799

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    Taschenbuch. Condizione: Neu. Antioxidant and Haemotological Properties of Nigella sativa, Carica papaya and Boswellia sacra. An Experiment | Kehinde Sowunmi | Taschenbuch | 36 S. | Englisch | 2020 | GRIN Verlag | EAN 9783346087799 | Verantwortliche Person für die EU: GRIN Publishing GmbH, Waltherstr. 23, 80337 München, info[at]grin[dot]com | Anbieter: preigu Print on Demand. …

  • Lingua: Inglese

    Editore: GRIN Verlag, 2019

    3346084264 / 9783346084262

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    Taschenbuch. Condizione: Neu. Proteomic and genomic techniques towards a better life in environmental research | Kehinde Sowunmi | Taschenbuch | 28 S. | Englisch | 2019 | GRIN Verlag | EAN 9783346084262 | Verantwortliche Person für die EU: GRIN Publishing GmbH, Waltherstr. 23, 80337 München, info[at]grin[dot]com | Anbieter: preigu Print on Demand. …

  • Lingua: Inglese

    Editore: GRIN Verlag Feb 2020, 2020

    3346075710 / 9783346075710

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    Da: buchversandmimpf2000, Emtmannsberg, BAYE, Germaniabuchversandmimpf2000

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    Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Research Paper (undergraduate) from the year 2014 in the subject Biology - Diseases, Health, Nutrition, Tai Solarin University of Education, course: Biology, language: English, abstract: There seems to be epidemiological associations between quality of life and cognitive failure yet, studies determining the relationship between quality of life indices and cognitive failure have been sparse. In addition, no studies examining this relationship have been carried out in Nigerian population. To determine the association between quality of life indices and cognitive failure in a Nigerian sample.A cross-sectional study of 1,338 participants with diverse age groups, ethnicity and socioeconomic levels from three different States and regions in Nigeria recruited from eleven public hospitals between May 2014 and August 2014. Cognitive failure in relation to quality of life domains centring on physical and occupational functioning, perceptions about health status, psychological and social functioning were determined using linear and logistic regressions after adjusting for age, ethnicity, education, gender, marital status, family type, alcohol and smoking status. In the adjusted models, four of the indices for measuring quality of life domains were significantly associated with cognitive failures: worrying about health problems (adjusted odds ratio [AOR], 1.095; 95% CI, 1.05-1.14), health-related impairment in daily activities (AOR, 1.138; 95% CI, 1.09-1.93) and increased hospitalization (AOR, 1.55; 95% CI, 1.24-1.94) were associated with increased cognitive failures whereas showing care for one's health (AOR, 0.93; 95% CI, 0.89-0.96) was associated with decreased levels of cognitive failure. Linear regression analysis on these data recapitulated these results. Quality of life research appears to be vital for health needs assessment of populations and could have profound implications for cognitive failure and other health-related outcome assessment in biology, medicine and health services research.GRIN Publishing GmbH, Waltherstraße 23, 80337 München 68 pp. Englisch.…

  • Lingua: Inglese

    Editore: GRIN Verlag, 2020

    3346075710 / 9783346075710

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    Da: preigu, Osnabrück, Germaniapreigu

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    EUR 42,95

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    Taschenbuch. Condizione: Neu. Association between cognitive failure and health related quality of life indices | Kehinde Sowunmi | Taschenbuch | 68 S. | Englisch | 2020 | GRIN Verlag | EAN 9783346075710 | Verantwortliche Person für die EU: GRIN Publishing GmbH, Waltherstr. 23, 80337 München, info[at]grin[dot]com | Anbieter: preigu Print on Demand. …