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Hardback or Cased Book. Condizione: New. Synthesis, Application and Biological Evaluation of Chemical Organic Compounds. Book.

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Taschenbuch. Condizione: Neu. Alternative methods for obtaining of cherylline derivatives | Stanimir Manolov (u. a.) | Taschenbuch | 52 S. | Englisch | 2017 | LAP LAMBERT Academic Publishing | EAN 9786202078573 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book are presented the results from research on alternative approaches towards the synthesis of 4- aryl-l,2,3,4-tetrhydroisoquinolines as synthetic analogues of the alkaloid cherylline. Optimal conditions for the synthesis of the required 2,2-disubstituted ethylamine precursors are found. The Schotten- Baumann method for amide synthesis is then successfully applied and the synthesized amides are used in an intramolecular -amidoalkylation reaction to obtain 4-substituted 1,2,3,4-tetrahydroisoquinolines. An eco-friendly procedure utilizing PPA/SiO2 catalyst for the intramolecular -amidoalkylation is developed. Microwave-assisted variant of this eco-friendly procedure is also successfully developed. By the Bischler-Napieralski method are synthesized five new 1,4- disubstituted-l,2,3,4-tetrahydroisoquinolines. These are potential inhibitors of DHODH. It is found that the reduction of 1,4-disubstituted 3,4-dihydroisoquinolines leads to formation of diastereoisomers. The diastereoisomers are successfully separated by preparative column chromatography and 2:1 (cis:trans) ratio is determined. This ratio is not affected by the temperature at which the reaction is carried out. 52 pp. Englisch.

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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Manolov StanimirStanimir Manolov received his B.Sc. of Computer chemistry (2008), M.Sc. (2009), and Ph.D. of Organic chemistry (2015) degrees from University of Plovdiv (Bulgaria). His research in the group of Prof. Iliyan Ivanov is .

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In this book are presented the results from research on alternative approaches towards the synthesis of 4- aryl-l,2,3,4-tetrhydroisoquinolines as synthetic analogues of the alkaloid cherylline. Optimal conditions for the synthesis of the required 2,2-disubstituted ethylamine precursors are found. The Schotten- Baumann method for amide synthesis is then successfully applied and the synthesized amides are used in an intramolecular ¿-amidoalkylation reaction to obtain 4-substituted 1,2,3,4-tetrahydroisoquinolines. An eco-friendly procedure utilizing PPA/SiO2 catalyst for the intramolecular ¿ -amidoalkylation is developed. Microwave-assisted variant of this eco-friendly procedure is also successfully developed. By the Bischler-Napieralski method are synthesized five new 1,4- disubstituted-l,2,3,4-tetrahydroisoquinolines. These are potential inhibitors of DHODH. It is found that the reduction of 1,4-disubstituted 3,4-dihydroisoquinolines leads to formation of diastereoisomers. The diastereoisomers are successfully separated by preparative column chromatography and 2:1 (cis:trans) ratio is determined. This ratio is not affected by the temperature at which the reaction is carried out.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 52 pp. Englisch.

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In this book are presented the results from research on alternative approaches towards the synthesis of 4- aryl-l,2,3,4-tetrhydroisoquinolines as synthetic analogues of the alkaloid cherylline. Optimal conditions for the synthesis of the required 2,2-disubstituted ethylamine precursors are found. The Schotten- Baumann method for amide synthesis is then successfully applied and the synthesized amides are used in an intramolecular -amidoalkylation reaction to obtain 4-substituted 1,2,3,4-tetrahydroisoquinolines. An eco-friendly procedure utilizing PPA/SiO2 catalyst for the intramolecular -amidoalkylation is developed. Microwave-assisted variant of this eco-friendly procedure is also successfully developed. By the Bischler-Napieralski method are synthesized five new 1,4- disubstituted-l,2,3,4-tetrahydroisoquinolines. These are potential inhibitors of DHODH. It is found that the reduction of 1,4-disubstituted 3,4-dihydroisoquinolines leads to formation of diastereoisomers. The diastereoisomers are successfully separated by preparative column chromatography and 2:1 (cis:trans) ratio is determined. This ratio is not affected by the temperature at which the reaction is carried out.

Buch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Discover the latest advancements in the world of chemical organic compounds with our Special Issue, 'Synthesis, Application, and Biological Evaluation.' Leading researchers have converged to showcase a diverse array of synthesized compounds, nanostructures, and extractions from plant and animal sources. Explore in silico analyses and biological assessments utilizing cutting-edge methodologies. Highlights: 1) Outstanding Antibacterial Activity: Chitosan/Fe(III)/deferoxamine nanoparticles outperform conventional drugs, showing promise in in vivo and in vitro applications. 2) Innovative Nanocomposites: Poly(o-anisidine)/BaSO4 nanocomposites exhibit potential antibacterial capabilities with tunable characteristics. 3) Novel Compounds: Discover N-acyl-¿-amino acids, 4H-1,3-oxazol-5-ones, 2-acylamino ketones, and 1,3-oxazoles with remarkable antibacterial and antioxidant properties. 4) Anti-Inflammatory Agents: Explore hybrid molecules with enhanced anti-inflammatory and antioxidant activity, outperforming standard drugs. 5) Osteoporosis Prevention: Ethanolic extracts of G. littoralis show promise in preventing osteoporosis. 6) Perfume Longevity: Deuterated ambrox extends perfume shelf life, a fascinating innovation in the fragrance industry.This Special Issue represents the cutting edge of chemical research and applications, offering solutions to global challenges. Join us in the pursuit of knowledge and innovation regarding chemical organic compounds.

Buch. Condizione: Neu. Synthesis, Application and Biological Evaluation of Chemical Organic Compounds | Buch | Englisch | 2023 | MDPI AG | EAN 9783036590677 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.