Susweta paul (10 risultati)

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Paperback. Condizione: Brand New. 104 pages. 8.66x5.91x0.24 inches. In Stock.

Taschenbuch. Condizione: Neu. In Silico studies on Triclosan, the FabI inhibitor and its analogues | A Study to counteract Cross resistance and Co resistance to drugs | Susweta Paul (u. a.) | Taschenbuch | 104 S. | Englisch | 2016 | LAP LAMBERT Academic Publishing | EAN 9783659956355 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Taschenbuch. Condizione: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Triclosan is a widely used biocide that is considered as an effective antimicrobial agent against different micro-organism. It is included in many consumer and personal health care product. Triclosan has a site specific action in the bacterial cells as an inhibitor of NADH or NADPH dependent enoyl-acyl carrier protein reductase. E.Coli FabI catalysis the reduction of enoyl-ACP during each cycle of fatty acid elongation and is inhibited by Triclosan. The list of analogues comprises of nonbiocidal, potent, FabI inhibitors which are similar to Triclosan. Based on docking results and IC50 values, shortlisted compounds are selected and 2D-QSAR studies validate the model of dataset of the shortlisted compounds which can be the nearly exact analogues of Triclosan. This validation is done with the help of statistical significances and virtual-ligand screening. The major concern is that Triclosan resistance may contribute to reduce susceptibility to clinically important anti-microbial, due to either cross resistance or co resistance mechanism. Widespread use of Triclosan may represent a potential public health risk 104 pp. Englisch.…

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Condizione: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Paul SuswetaSusweta Paul graduated from the University of Calcutta in Biochemistry in 2011.She did her Masters in Bioinformatics from Birla Institute of Technology, Mesra in 2013. Her research interests involve drug-protein interacti.…

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Taschenbuch. Condizione: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Triclosan is a widely used biocide that is considered as an effective antimicrobial agent against different micro-organism. It is included in many consumer and personal health care product. Triclosan has a site specific action in the bacterial cells as an inhibitor of NADH or NADPH dependent enoyl-acyl carrier protein reductase. E.Coli FabI catalysis the reduction of enoyl-ACP during each cycle of fatty acid elongation and is inhibited by Triclosan. The list of analogues comprises of nonbiocidal, potent, FabI inhibitors which are similar to Triclosan. Based on docking results and IC50 values, shortlisted compounds are selected and 2D-QSAR studies validate the model of dataset of the shortlisted compounds which can be the nearly exact analogues of Triclosan. This validation is done with the help of statistical significances and virtual-ligand screening. The major concern is that Triclosan resistance may contribute to reduce susceptibility to clinically important anti-microbial, due to either cross resistance or co resistance mechanism. Widespread use of Triclosan may represent a potential public health riskVDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 104 pp. Englisch.…

Taschenbuch. Condizione: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Triclosan is a widely used biocide that is considered as an effective antimicrobial agent against different micro-organism. It is included in many consumer and personal health care product. Triclosan has a site specific action in the bacterial cells as an inhibitor of NADH or NADPH dependent enoyl-acyl carrier protein reductase. E.Coli FabI catalysis the reduction of enoyl-ACP during each cycle of fatty acid elongation and is inhibited by Triclosan. The list of analogues comprises of nonbiocidal, potent, FabI inhibitors which are similar to Triclosan. Based on docking results and IC50 values, shortlisted compounds are selected and 2D-QSAR studies validate the model of dataset of the shortlisted compounds which can be the nearly exact analogues of Triclosan. This validation is done with the help of statistical significances and virtual-ligand screening. The major concern is that Triclosan resistance may contribute to reduce susceptibility to clinically important anti-microbial, due to either cross resistance or co resistance mechanism. Widespread use of Triclosan may represent a potential public health risk.…